Abstract:
:With the intent of cost containment, we conducted a survey of cimetidine usage in the Ambulatory Care Service of our Veterans Administration Medical Center. During a period of six months, this drug was prescribed for 132 patients. Only about 20% received cimetidine for FDA approved conditions. Treated conditions not approved by the FDA (unlabeled) included undiagnosed abdominal pain, past peptic ulcer disease, reflux esophagitis, and a variety of other conditions. Fourteen percent of the patients had demanded the drug. Irrespective of whether a confirmed diagnosis was present or not, most patients taking cimetidine had symptomatic relief. It is unclear whether more regulations or improved physician education would be the better method to control improper and unnecessary use of a drug that is generally safe but has potentially serious side effects.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Thomas CT,Thomas E,Reddy KR,Martin E,Stapleton JAdoi
10.1097/00007611-198410000-00019subject
Has Abstractpub_date
1984-10-01 00:00:00pages
1281-2issue
10eissn
0038-4348issn
1541-8243journal_volume
77pub_type
杂志文章abstract::This article first reviews the evidence for and against chronic opioid therapy. Evidence supporting the opioid responsiveness of chronic pain, including neuropathic pain, includes multiple randomized trials conducted over months (up to 8 months). Observational studies are conducted for longer, and many also support op...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000223946.19256.17
更新日期:2006-11-01 00:00:00
abstract::We have described a 38-year-old woman with a lesion of the cervix found on routine physical examination. The lesion proved to be a primary leiomyosarcoma of the cervix. Despite radiation therapy, surgery, and chemotherapy, the tumor recurred and grew relentlessly. She is alive with disease at two years seven months af...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198104000-00042
更新日期:1981-04-01 00:00:00
abstract:OBJECTIVES:To design and implement a formal otolaryngology inpatient consultation service that improves satisfaction of consulting services, increases educational opportunities, improves the quality of patient care, and ensures sustainability after implementation. METHODS:This was a retrospective cohort study in a lar...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000763
更新日期:2018-02-01 00:00:00
abstract::Liver cysts are a well-recognized feature of autosomal dominant polycystic kidney disease (ADPKD) and occur in 77% of patients more than 60 years old. Serious sequelae, however, are rare, the two most common complications being pain and cyst infections. Portal hypertension has been reported in ADPKD due to the rare pr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199906000-00015
更新日期:1999-06-01 00:00:00
abstract::Acute methemoglobinemia is a medical emergency that can rapidly become fatal. A substantial number of drugs, including topical preparations, can precipitate this condition. I report a rare example of severe, acute methemoglobinemia caused by oropharyngeal anesthesia with topical benzocaine spray for orogastric intubat...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199709000-00018
更新日期:1997-09-01 00:00:00
abstract::Forty consecutive patients having left ventricular (LV) aneurysmectomy were evaluated for surgical risk predictors and were then followed up after operation. Factors evaluated included age, time since last myocardial infarction, NYHA classification, principal indication for surgery, LV end diastolic pressure, LV "A" w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198005000-00018
更新日期:1980-05-01 00:00:00
abstract::We evaluated a perinatal outreach education program to determine its "transportability" (usefulness to other regional centers). Three kinds of data were available from seven regional centers: (1) participation in the program by health care providers, (2) changes in cognitive knowledge, and (3) changes in neonatal care...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198312000-00009
更新日期:1983-12-01 00:00:00
abstract::We have described a case of maternal primary aldosteronism in which there is virilization of the female offspring. The most common causes of virilization are considered unlikely on the basis of clinical and laboratory data. The report illustrates the exacerbation of aldosteronism that occurs postpartum and emphasizes ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1983-04-01 00:00:00
abstract::Sections from 879 consecutive breast biopsies performed for clinically and grossly benign disease between 1962 and 1966 were reviewed. Twenty-four cases of undiagnosed lobular carcinoma in situ or atypical lobular hyperplasia and six cases of intraductal papillary carcinoma were found. Only one patient later developed...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197804000-00004
更新日期:1978-04-01 00:00:00
abstract::We have presented a case of primary testicular carcinoid in an otherwise asymptomatic 50-year-old white man treated by right orchiectomy; a postoperative abdominal CT scan was normal. Histologically and cytologically the tumor resembled carcinoids of midgut origin. Most primary testicular carcinoid tumors are not clin...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198802000-00032
更新日期:1988-02-01 00:00:00
abstract::Electrical injuries may occur from high or low voltage contact. Low voltage injuries usually occur in the home, tetany may lead to sustained contact, and dangerous cardiac disturbances often result. High voltage injuries are usually work related and result from brief contact but may cause serious tissue destruction an...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2000-12-01 00:00:00
abstract::In the last five years, much information has been gathered about the efficacy of several technics for managing obesity. Hospitalization with fasting, surgery, drugs, weight reducing clubs, and behavior modification methods have proven efficacious for select groups of obese individuals. Methods of behavior modification...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197602000-00004
更新日期:1976-02-01 00:00:00
abstract::In the ten-year period from 1978 through 1987, 261 patients with intussusception were admitted to Chang Gung Memorial Hospital. The diagnosis was established by barium enema or at laparotomy. The patients were divided into two groups; there were 228 children ranging in age from 1 month to 14 years, and 33 adults. Amon...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::This article documents distributional patterns of allopathic family practice physicians (including general practitioners) in Texas as compared with allopathic physicians in all other medical specialties in the state during the period 1969-1973, for which there are reliable data. Statistical analysis of this informatio...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197709000-00007
更新日期:1977-09-01 00:00:00
abstract::Diagnostic peritoneal lavage (DPL) is an established procedure in evaluation of trauma victims but is less well established for use in patients suspected of having acute intra-abdominal disease. Twenty-six seriously ill patients at our institution who had DPL for acute intra-abdominal disease form the basis of this re...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199004000-00015
更新日期:1990-04-01 00:00:00
abstract:OBJECTIVES:The authors sought to explore patients' views about discussing spiritual issues with primary care physicians, including perceived barriers to and facilitators of discussions. METHODS:The study was a qualitative, semistructured interview of 10 chronically or terminally ill patients who were deliberately sele...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000146486.69217.EE
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:Osteopenia is considerably more common than osteoporosis and accounts for most of the fracture burden in women older than 50 years. It is uncertain when to initiate treatment in osteopenia. We sought to determine in women with osteopenia what effect transitioning to lower categories had on subsequent fractur...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000410
更新日期:2016-02-01 00:00:00
abstract::This descriptive study prospectively examined the performance and supervision of interpretive and procedural skills during an internal medicine clerkship. Students (N = 150) documented having done 7 required and 12 elective skills. Preceptors of required skills were interns (44%), residents (29%), attending physicians...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199606000-00009
更新日期:1996-06-01 00:00:00
abstract::Ours is apparently the first reported pediatric case of Stomatococcus mucilaginosus bacteremia. It is the second reported case of S mucilaginosus catheter-associated infection, but the first case successfully treated without removing the central venous catheter. This unusual organism should be added to the list of opp...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199103000-00029
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVES:In 2014, 726 bicyclists were killed and an additional 50,000 were injured in crashes with motor vehicles. The number of cyclists in the United States is increasing, and as a result there has been a call for more bike lanes. We examined the difference in the severity of injury of bicyclists involved in motor ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000665
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Recent studies on the impact of rib fractures after blunt trauma have shown a linear relationship between age, increasing number of rib fractures, and complications, including mortality. Others have documented that age-related morbidity increases before age 65 in trauma patients. We hypothesize that patients...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000203815.29757.d3
更新日期:2006-04-01 00:00:00
abstract::Survival of infants with necrotizing enterocolitis may be complicated by intestinal stricture(s) as a result of healing of ischemic segments of bowel. An asymptomatic cecal stenosis not visible on barium enema was identified at operation for reestablishment of intestinal continuity. Infants recovering from acute necro...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197912000-00039
更新日期:1979-12-01 00:00:00
abstract::A 3-year-old white boy had symptomatic thrombocytopenia after receiving trimethoprim-sulfamethoxazole in recommended doses for one week. The platelet count returned to normal soon after the medication was discontinued. In vitro admixing of donor platelets with a sample of the patient's serum demonstrated antiplatelet ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198105000-00039
更新日期:1981-05-01 00:00:00
abstract:OBJECTIVES:Despite the efforts of various leading organizations in medical education, representation of black students in US medical schools has declined since the mid-1990s. The Florida State University College of Medicine (FSUCOM) has undertaken efforts to increase black and other underrepresented minority in medicin...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000792
更新日期:2018-04-01 00:00:00
abstract::The comparative value of palpation, light percussion, and auscultatory percussion for detecting the liver below costal margin was studied in 45 normal subjects and 20 patients. The presence of the liver 2 cm or more below the costal margin was considered abnormal, since this organ was found no more than 1 cm below in ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199402000-00006
更新日期:1994-02-01 00:00:00
abstract:INTRODUCTION:Pathologic gambling is a disorder with features that implicate abnormal functioning in brain regions involved in addiction, mood, anxiety, and impulse control disorders. Our goal was to examine brain function with neurocognitive tasks that target these brain regions in patients with pathologic gambling. M...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000197583.24072.f5
更新日期:2006-01-01 00:00:00
abstract::Two cases of postoperative death due to unsuspected pheochromocytoma are presented. Both patients exhibited signs and symptoms preoperatively which might have been attributable to a pheochromocytoma. These reports serve as a reminder of the potentially fatal consequences of inadequate evaluation of hypertensive patien...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197711000-00023
更新日期:1977-11-01 00:00:00
abstract:BACKGROUND:This study was done to determine the accuracy of the 2 x 2 cm pocket identifying low amniotic fluid (AF) volume in singleton and twin pregnancies. METHODS:The AF volume was evaluated by ultrasonography for the presence of a 2 x 2 cm pocket before amniocentesis. The actual AF volume was then determined by a ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199908000-00011
更新日期:1999-08-01 00:00:00
abstract::We present the case of a 59-year-old woman with an International Federation of Gynecology and Obstetrics stage IIIB serous psammocarcinoma. Only 12 cases of this rare ovarian neoplasm have been reported previously. These tumors act like borderline tumors and, therefore, do not usually require chemotherapy or radiation...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199805000-00015
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:In this study, the clinical characteristics, survival, and prognostic factors of 200 patients diagnosed as having chronic lymphocytic leukemia (CLL) were analyzed. METHODS:The medical charts of 200 CLL patients registered to our center between 1984 and 2000 were retrospectively evaluated. RESULTS:Of all pa...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000053674.03385.B7
更新日期:2004-03-01 00:00:00