Lung distensibility and airway function in asthmatic children.

abstract：:An important feature of the role of IgA in protection against infection and disease at the level of the mucosal surfaces might be the elimination of pathogens without induction of a strong inflammatory reaction. In the present study we addressed the question whether IgA has a regulatory effect on the generation of rea...

journal_title：Pediatric research

authors： Wolf HM,Vogel E,Fischer MB,Rengs H,Schwarz HP,Eibl MM

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:After birth, breastfeeding is the exclusive source of hormonal signaling between mother and infant. Hospitalized infants often receive donor milk when their own mother's milk is unavailable. METHODS:The presence of insulin, leptin, cortisol, progesterone, and testosterone was examined in samples from milk b...

journal_title：Pediatric research

authors： Vass RA,Bell EF,Colaizy TT,Schmelzel ML,Johnson KJ,Walker JR,Ertl T,Roghair RD

更新日期：2020-10-01 00:00:00

abstract：:BACKGROUNDThe aims of this study were to (i) compare the concentrations of two neural injury markers, S100B protein and neuron-specific enolase (NSE), in intrauterine growth-restricted (IUGR) fetuses and in fetuses with appropriate growth-for-gestational-age (AGA), and (ii) investigate potential relationships between ...

journal_title：Pediatric research

authors： Mazarico E,Llurba E,Cumplido R,Valls A,Melchor JC,Iglesias M,Cabero L,Gratacós E,Gómez-Roig MD

更新日期：2017-09-01 00:00:00

abstract：:The isobutyryl-CoA dehydrogenase (IBD) enzyme is involved in the degradation of valine. IBD deficiency was first reported in 1998 and subsequent genetic investigations identified acyl-CoA dehydrogenase (ACAD) 8, now IBD, as the gene responsible for IBD deficiency. Only three individuals homozygous or compound heterozy...

journal_title：Pediatric research

authors： Pedersen CB,Bischoff C,Christensen E,Simonsen H,Lund AM,Young SP,Koeberl DD,Millington DS,Roe CR,Roe DS,Wanders RJ,Ruiter JP,Keppen LD,Stein Q,Knudsen I,Gregersen N,Andresen BS

更新日期：2006-09-01 00:00:00

abstract：:The age-related changes in fasting arterial levels of energy substrates and insulin were studied at birth and/or 6 wk in eleven baboon infants. In addition, the renal contribution to glucose release in the primate infant was estimated. Arterial blood glucose levels were similar in six fasted newborns and in nine faste...

journal_title：Pediatric research

authors： Levitsky LL,Paton JB,Fisher DE,Delannoy CW

更新日期：1980-08-01 00:00:00

abstract：:Ambient oxygen concentration and vascular endothelial growth factor (VEGF)-A are vital in lung development. Since hypoxia stimulates VEGF-A production and hyperoxia reduces it, we hypothesized that VEGF-A down-regulation by exposure of airways to hyperoxia may result in abnormal lung development. An established model ...

journal_title：Pediatric research

authors： Esquibies AE,Bazzy-Asaad A,Ghassemi F,Nishio H,Karihaloo A,Cantley LG

更新日期：2008-01-01 00:00:00

abstract：:Cell-based therapies hold significant promise for infants at risk for cerebral palsy (CP) from perinatal brain injury (PBI). PBI leading to CP results from multifaceted damage to neural cells. Complex developing neural networks are injured by neural cell damage plus unique perturbations in cell signaling. Given that c...

journal_title：Pediatric research

authors： Jantzie LL,Scafidi J,Robinson S

更新日期：2018-01-01 00:00:00

abstract：:Ethylmalonic aciduria is a common biochemical finding in patients with inborn errors of short chain fatty acid beta-oxidation. The urinary excretion of ethylmalonic acid (EMA) may stem from decreased oxidation by short chain acyl-CoA dehydrogenase (SCAD) of butyryl-CoA, which is alternatively metabolized by propionyl-...

journal_title：Pediatric research

authors： Corydon MJ,Gregersen N,Lehnert W,Ribes A,Rinaldo P,Kmoch S,Christensen E,Kristensen TJ,Andresen BS,Bross P,Winter V,Martinez G,Neve S,Jensen TG,Bolund L,Kølvraa S

更新日期：1996-06-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Pediatric research

authors： Chaudhry AA,Castro-Magana M,Aloia JF,Yeh JK,Guevarra MS

更新日期：2020-04-01 00:00:00

abstract：:Twenty-two reported cases of neuroblastoma missed by the mass screening programs were reviewed (six cases in Sapporo City where a quantitative measurement for both vanillylmandelic acid (VMA) and homovanillic acid (HVA) is used and 16 cases in the districts of qualitative judgment only for VMA), and some potential fac...

journal_title：Pediatric research

authors： Nishi M,Miyake H,Takeda T,Takasugi N,Sato Y,Hanai J,Kawai T

更新日期：1989-12-01 00:00:00

abstract：:The objective was to investigate any possible relationship between functional and structural vascular changes in women with low gestational age and/or low birth weight by analyzing the retinal vascular pattern in women with thoroughly documented blood pressure. Retinal vessel morphology was evaluated by digital image ...

journal_title：Pediatric research

authors： Kistner A,Jacobson L,Jacobson SH,Svensson E,Hellstrom A

更新日期：2002-06-01 00:00:00

abstract：:The prevalence of iron deficiency was determined in Göteborg, Sweden, in a sample of 15- to 16-y-old girls (n = 220) and boys (n = 207) using serum ferritin (SF). In a recent study in women on the relationship between SF and stainable bone marrow iron, it was established that at a cutoff value for SF of < 16 microgram...

journal_title：Pediatric research

authors： Hallberg L,Hultén L,Lindstedt G,Lundberg PA,Mark A,Purens J,Svanberg B,Swolin B

更新日期：1993-11-01 00:00:00

abstract：:In studies in the newborn infant, it is often assumed that there are similarities in airflow in successive breaths, and, therefore, it is only necessary to measure parameters in a small number of breaths. However, other studies have shown considerable variability in breathing patterns in successive breaths. It was, th...

journal_title：Pediatric research

authors： Hathorn MK

更新日期：2000-07-01 00:00:00

abstract：:Immunosuppressive effects of carrageenan, a high-molecular-weight polysaccharide, on antibody and T cell responses have been previously demonstrated. However, its effect on anaphylaxis is unknown. Our objectives were to test carrageenan-mediated oral tolerance induction in young mice subsequently sensitized to a commo...

journal_title：Pediatric research

authors： Frossard CP,Hauser C,Eigenmann PA

更新日期：2001-03-01 00:00:00

abstract：:The absolute and the percentage plasma NEFA pattern of healthy children, Cystic Fibrosis (C.F.) patients and their parents have been determined (table I, III, V) and compared with those of age and sex matched control subjects (table II, Iv, V). There is a striking difference in the percentage plasma NEFA pattern of C....

journal_title：Pediatric research

authors： Rogiers V,Dab I,Crokaert R,Vis HL

更新日期：1980-09-01 00:00:00

abstract：:To determine whether human milk contained soluble receptors and cytokine antagonists that might contribute to its anti-inflammatory properties, ELISA and enzyme-amplified sensitivity immunoassay methods were used to quantitate soluble intercellular and vascular cell adhesion molecules, soluble E-selectin, soluble IL-6...

journal_title：Pediatric research

authors： Buescher ES,Malinowska I

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Toll-like receptor (TLR)-mediated inflammation may contribute to neonatal sepsis, for which pentoxifylline (PTX), a phosphodiesterase inhibitor that raises intracellular cAMP, is a candidate adjunctive therapy. We characterized the anti-inflammatory effects of PTX toward TLR-mediated production of inflammato...

journal_title：Pediatric research

authors： Speer EM,Dowling DJ,Ozog LS,Xu J,Yang J,Kennady G,Levy O

更新日期：2017-05-01 00:00:00

abstract：:Epidermal growth factor (EGF) and transforming growth factor-alpha (TGF-alpha) are mitogenic to the intestinal epithelium. To further clarify their role in the developing human fetal gut, their expression was studied in fetuses at 15 to 20 wk of gestation. TGF-alpha mRNA was present throughout the gastrointestinal tra...

journal_title：Pediatric research

authors： Miettinen PJ

更新日期：1993-05-01 00:00:00

abstract：:Chronic disease risk is inextricably linked to our early-life environment, where maternal, fetal, and childhood factors predict disease risk later in life. Currently, maternal obesity is a key predictor of childhood obesity and metabolic complications in adulthood. Although the mechanisms are unclear, new and emerging...

journal_title：Pediatric research

authors： Gohir W,Ratcliffe EM,Sloboda DM

更新日期：2015-01-01 00:00:00

abstract：:Five patients with Bartter's syndrome were investigated. Sodium restriction (less than 10 mEq/day for at least 5 days) showed a renal sodium wastage in only two patients (I and II) in spite of increased aldosterone secretion rate (from 151-427 to 680-842 mug/day). The effect of angiotensin II (A II) 80ng/kg/min for 30...

journal_title：Pediatric research

authors： Sann L,David M,Richard P,Floret D,Sassard J,Bizollon CA,Francois R

更新日期：1976-12-01 00:00:00

abstract：:Hypothermia is a frequent occurrence in newborns, and thermoregulatory management is a fundamental part of medical stabilization. Although modest reduction in brain temperature (2-3 degrees C) before ischemia provides neuroprotection in adults, the effect of modest hypothermia on immature brain has not been examined. ...

journal_title：Pediatric research

authors： Laptook AR,Corbett RJ,Sterett R,Burns DK,Tollefsbol G,Garcia D

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Social determinants of health (SDH) can substantially impact health outcomes. A systematic review, however, has never been conducted on associations of SDH with congenital heart disease (CHD) outcomes. The aim, therefore, was to conduct such a systematic review. METHODS:Seven databases were searched through...

journal_title：Pediatric research

authors： Davey B,Sinha R,Lee JH,Gauthier M,Flores G

更新日期：2020-10-17 00:00:00

abstract：:The zeta subunit of the CD3 T-cell receptor complex and the major histocompatibility complex class 1 (MHC-I) are important not only for the immune response to antigens, they also function as signal molecules in the brain, where they play a role in the postnatal maturation process. The expression of these molecules can...

journal_title：Pediatric research

authors： Sourial-Bassillious N,Eklöf AC,Scott L,Aperia A,Zelenin S

更新日期：2006-10-01 00:00:00

abstract：:Indomethacin, because of its prostaglandin inhibition, may cause constriction of the ductus arteriosus and affect the pulmonary circulation. To study this possibility, we gave indomethacin daily by gavage to two groups of pregnant rats from the 17th day of pregnancy through delivery (group 1, 2 mg/kg/day; group 2, 4 m...

journal_title：Pediatric research

authors： Harker LC,Kirkpatrick SE,Friedman WF,Bloor CM

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:Aberrant immune responses play a key role in the pathogenesis of inflammatory bowel disease (IBD). Most studies conducted to delineate the underlying molecular mechanisms focus on adults; an understanding of these mechanisms in children remains to be determined. Here, cytokines and transcription factors prod...

journal_title：Pediatric research

authors： Busch MA,Gröndahl B,Knoll RL,Pretsch L,Doganci A,Hoffmann I,Kullmer U,Bähner V,Zepp F,Meyer CU,Gehring S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Secreted frizzled-related protein 5 (SFRP5) is an adipokine protecting against obesity-related insulin resistance and diabetes. SFRP5 binds to wingless type mouse mammary tumor virus (MMTV) integration site family member 5A (WNT5A) to improve insulin sensitivity. We performed the first study of SFRP5 and WNT...

journal_title：Pediatric research

authors： Prats-Puig A,Soriano-Rodríguez P,Carreras-Badosa G,Riera-Pérez E,Ros-Miquel M,Gomila-Borja A,de Zegher F,Ibáñez L,Bassols J,López-Bermejo A

更新日期：2014-06-01 00:00:00

abstract：:To assess sleep organization in premature infants of < 35 wk gestational age (w GA), we performed polygraphic recordings in 24 neurologically normal neonates (eight per group): artificially ventilated 27-30 and 31-34 w GA infants and nonventilated 31-34 w GA infants. Sleep states were defined by concordance of EEG and...

journal_title：Pediatric research

authors： Curzi-Dascalova L,Figueroa JM,Eiselt M,Christova E,Virassamy A,d'Allest AM,Guimarâes H,Gaultier C,Dehan M

更新日期：1993-11-01 00:00:00

abstract：:Children with inborn errors of urea synthesis who survive neonatal hyperammonemic coma commonly exhibit cognitive deficits and neurologic abnormalities. Yet, there is evidence that ammonia is not the only neurotoxin. Hyperammonemia appears to induce a number of neurochemical alterations. In rodent models of hyperammon...

journal_title：Pediatric research

authors： Robinson MB,Heyes MP,Anegawa NJ,Gorry E,Djali S,Mellits ED,Batshaw ML

更新日期：1992-10-01 00:00:00

abstract：:Fifty patients with haemophilia B, belonging to 29 kindreds, were investigated with a highly sensitive immunoradiometric assay based on a homologous antibody to factor IX. The assay measures factor IX antigen (f.IX:Ag) in plasma down to 0.025 U/dl. Seventeen of 18 investigated patients with severe haemophilia B had ve...

journal_title：Pediatric research

authors： Ljung R,Holmberg L

更新日期：1982-03-01 00:00:00

abstract：:In persistent hyperinsulinemic hypoglycemia of infancy, ketone body concentrations are abnormally low at times of hypoglycemia, depriving the brain of its most important alternative fuel. The neuroprotective effect of endogenous ketone bodies is evidenced by animal and human studies, but knowledge about exogenous supp...

journal_title：Pediatric research

authors： Plecko B,Stoeckler-Ipsiroglu S,Schober E,Harrer G,Mlynarik V,Gruber S,Moser E,Moeslinger D,Silgoner H,Ipsiroglu O

更新日期：2002-08-01 00:00:00