Review article: the epidemiology and prevention of gastric cancer.

abstract：:Endoscopic procedures generate bacteraemia to different degrees. Under certain conditions, most notably valvular heart disease, clinically significant infections may occur. A large body of literature has grown around recommendations for antibiotic prophylaxis to prevent procedure-related infections. Most of this liter...

journal_title：Alimentary pharmacology & therapeutics

authors： Schembre D,Bjorkman DJ

更新日期：1993-08-01 00:00:00

abstract：:In a double-blind parallel-group study, 98 patients with symptomatic duodenal ulcer received omeprazole 20 mg o.m. and 91 cimetidine 800 mg nocte for 2 or, if then not healed, 4 weeks. After 2 weeks the healing rates on an intention-to-treat basis were: for omeprazole 62% and for cimetidine 33% (P less than 0.001), an...

journal_title：Alimentary pharmacology & therapeutics

authors： Crowe JP,Wilkinson SP,Bate CM,Willoughby CP,Peers EM,Richardson PD

更新日期：1989-02-01 00:00:00

abstract：:Intestinal failure is a specific disease entity resulting from intestinal resection or disease-associated malabsorption and characterized by the inability to maintain protein-energy, fluid, electrolyte or micronutrient balance. We performed a MEDLINE search (1966-2006) to identify relevant articles, using keywords int...

journal_title：Alimentary pharmacology & therapeutics

authors： Lal S,Teubner A,Shaffer JL

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Although incrimination of the intestinal microbiota in the pathogenesis of IBD is widely accepted, few data are available about the role of specific bacteria. Potentially, Faecalibacterium prausnitzii, bacteria with anti-inflammatory properties, might be deficient in ulcerative colitis (UC). AIM:To quantify...

journal_title：Alimentary pharmacology & therapeutics

authors： Varela E,Manichanh C,Gallart M,Torrejón A,Borruel N,Casellas F,Guarner F,Antolin M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Recent evidence found probiotics could inhibit Helicobacter pylori colonization from both in vitro and in vivo studies. AIM:To systematically evaluate whether adding probiotics to anti-H. pylori regimens could improve eradication rates and reduce side effects during anti-H. pylori treatment. METHODS:Eligib...

journal_title：Alimentary pharmacology & therapeutics

authors： Tong JL,Ran ZH,Shen J,Zhang CX,Xiao SD

更新日期：2007-01-15 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease is prevalent in affluent countries and is a cause of cirrhosis and possibly hepatocellular carcinoma. AIM:To examine the clinical and histological features of biopsy-proven non-alcoholic fatty liver disease and investigate the predictors of severe histological disease in Ch...

journal_title：Alimentary pharmacology & therapeutics

authors： Wong VW,Chan HL,Hui AY,Chan KF,Liew CT,Chan FK,Sung JJ

更新日期：2004-07-01 00:00:00

abstract：AIM:To measure 24-h ambulatory oesophageal pH data in patients with gastro-oesophageal reflux disease prior to, during and after acute treatment with comparable doses of omeprazole and ranitidine. METHODS:The subjects were 20 adults with at least 8% acid contact time. Ten subjects were treated for 1 week with omeprazo...

journal_title：Alimentary pharmacology & therapeutics

authors： Orr WC,Mellow MH,Grossman MR

更新日期：1995-10-01 00:00:00

abstract：:Colorectal cancer is a common cancer and common cause of death. The mortality rate from colorectal cancer can be reduced by identification and removal of cancer precursors, adenomas, or by detection of cancer at an earlier stage. Pilot screening programmes have demonstrated decreased colorectal cancer mortality; as a ...

journal_title：Alimentary pharmacology & therapeutics

authors： Nicholson FB,Barro JL,Atkin W,Lilford R,Patnick J,Williams CB,Pignone M,Steele R,Kamm MA

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:It has been suggested that coeliac disease (CD) is associated with several neurological diseases. However, the evidence of such an association is inconclusive as earlier research has often been based on small numbers with retrospective data collection. AIM:To use Cox regression to examine the risk of neurol...

journal_title：Alimentary pharmacology & therapeutics

authors： Ludvigsson JF,Olsson T,Ekbom A,Montgomery SM

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Up to 80% of patients with Crohn's disease require an abdominal operation in their lifetime. As the use of vedolizumab is increasing for the treatment of Crohn's disease, it is important to understand its potential association with post-operative complications. AIM:We sought to compare 30-day postoperative ...

journal_title：Alimentary pharmacology & therapeutics

authors： Lightner AL,McKenna NP,Tse CS,Raffals LE,Loftus EV Jr,Mathis KL

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Randomized, placebo controlled trials are used to assess the efficacy of therapies for Crohn's disease. The placebo response and remission rates vary among studies. AIM:To analyse how the placebo response and remission rates in Crohn's trials have changed over time in the era of parenteral biologic therapie...

journal_title：Alimentary pharmacology & therapeutics

authors： Gallahan WC,Case D,Bloomfeld RS

更新日期：2010-01-01 00:00:00

abstract：:An elevated platelet count is well recognized as a marker of inflammatory bowel disease activity. There is an increased incidence of systemic thromboembolism in this disease. Recent work indicates that platelets exhibit several proinflammatory properties including release of inflammatory mediators, and recruitment, ch...

journal_title：Alimentary pharmacology & therapeutics

authors： Collins CE,Rampton DS

更新日期：1997-04-01 00:00:00

abstract：:In a double-blind crossover study, lower oesophageal sphincter pressure (LOSP) and distal oesophageal motility were studied in eight healthy volunteers following a single intravenous dose of omeprazole or placebo. Lower oesophageal sphincter pressure was determined before and at intervals up to 120 min after intraveno...

journal_title：Alimentary pharmacology & therapeutics

authors： Chakraborty TK,De Caestecker JS,Pryde A,Heading RC

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Patients with chronic hepatitis B (CHB) need long-term antiviral treatment with nucleos(t)ide analogues (NA). Animal studies suggest that some NA may increase cancer risk, but human data are lacking. AIM:To investigate cancer risks in patients with or without NA treatment. METHODS:We conducted a territory-...

journal_title：Alimentary pharmacology & therapeutics

authors： Wong GL,Tse YK,Yip TC,Chan HL,Tsoi KK,Wong VW

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Surveillance colonoscopy is recommended for inflammatory bowel disease (IBD) patients with longstanding extensive colitis (LEC). AIMS:To assess modalities and results of colonoscopic surveillance in a subset of CESAME cohort patients at high risk of colorectal cancer (CRC) and followed in university French ...

journal_title：Alimentary pharmacology & therapeutics

authors： Vienne A,Simon T,Cosnes J,Baudry C,Bouhnik Y,Soulé JC,Chaussade S,Marteau P,Jian R,Delchier JC,Coffin B,Admane H,Carrat F,Drouet E,Beaugerie L

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Liver transplantation (LT) offers a possible cure for carefully selected patients with hepatocellular carcinoma (HCC). Studies report that preoperative alpha-fetoprotein (AFP) is a prognostic indicator that can predict survival and recurrence in these patients. AIM:To undertake a systematic review of availa...

journal_title：Alimentary pharmacology & therapeutics

authors： Hakeem AR,Young RS,Marangoni G,Lodge JP,Prasad KR

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Anti-TNF agents are now widely used in Crohn's disease (CD), and in ulcerative colitis (UC). AIM:To review the safety profile of anti-TNF agents in all patients treated with infliximab in Edinburgh from 1999 to 2007. METHODS:Complete data were available on 202/207 patients comprising 157 CD, 42 UC and thre...

journal_title：Alimentary pharmacology & therapeutics

authors： Lees CW,Ali AI,Thompson AI,Ho GT,Forsythe RO,Marquez L,Cochrane CJ,Aitken S,Fennell J,Rogers P,Shand AG,Penman ID,Palmer KR,Wilson DC,Arnott ID,Satsangi J

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Malnutrition and jaundice are independent prognostic factors in cirrhosis. AIM:To assess the impact of enteral nutrition on the survival of alcoholic cirrhotic patients with jaundice but without acute alcoholic hepatitis. METHODS:The study was a multicentre prospective randomised controlled trial comparing...

journal_title：Alimentary pharmacology & therapeutics

authors： Dupont B,Dao T,Joubert C,Dupont-Lucas C,Gloro R,Nguyen-Khac E,Beaujard E,Mathurin P,Vastel E,Musikas M,Ollivier I,Piquet MA

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:In vitro studies suggest interactions between mesalazine (mesalamine) and thiopurines by thiopurine S-methyltransferase (TPMT) inhibition, influencing the balance of hepatotoxic 6-methylmercaptopurine ribonucleotide and immunosuppressive tioguanine (thioguanine) metabolites. AIM:To examine the in vivo pharm...

journal_title：Alimentary pharmacology & therapeutics

authors： Gilissen LP,Bierau J,Derijks LJ,Bos LP,Hooymans PM,van Gennip A,Stockbrügger RW,Engels LG

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Recent data suggest a role for high-dose oral proton pump inhibition in ulcer bleeding. AIM:To compare the cost-effectiveness of oral high-dose proton pump inhibition to both high-dose intravenous proton pump inhibition and placebo administration. METHODS:The model adopted a 30-day time horizon, and focuse...

journal_title：Alimentary pharmacology & therapeutics

authors： Barkun AN,Herba K,Adam V,Kennedy W,Fallone CA,Bardou M

更新日期：2004-07-15 00:00:00

abstract：BACKGROUND:In behavioural economics, a 'nudge' describes configuration of a choice to encourage a certain action without taking away freedom of choice. AIM:To determine the impact of a 'nudge' strategy - prefilling either 3mL or 5mL syringes with midazolam - on endoscopic sedation practice. METHODS:Consecutive patien...

journal_title：Alimentary pharmacology & therapeutics

authors： Harewood GC,Clancy K,Engela J,Abdulrahim M,Lohan K,O'Reilly C

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:With the global efforts to eradicate hepatitis C virus (HCV), treatment during pregnancy is becoming a priority for research as this, and maternal cure should reduce vertical transmission. However, as information on the efficacy and safety of direct-acting antivirals (DAAs) in pregnancy is generally lacking,...

journal_title：Alimentary pharmacology & therapeutics

authors： Freriksen JJM,van Seyen M,Judd A,Gibb DM,Collins IJ,Greupink R,Russel FGM,Drenth JPH,Colbers A,Burger DM

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Abnormal gall-bladder motility has been reported in diabetics. The objective was to evaluate the effect of chronic D2-dopamine receptor inhibition on gall-bladder emptying in diabetic patients. METHODS:Under double-blind placebo-controlled conditions and according to a crossover design, patients were random...

journal_title：Alimentary pharmacology & therapeutics

authors： Mansi C,Savarino V,Vigneri S,Sciabà L,Perilli D,Mele MR,Celle G

更新日期：1995-04-01 00:00:00

abstract：:Beta adrenoreceptor blocking drugs have been used for the prevention of haemorrhage from oesophageal varices. However, it is possible that these agents, by virtue of their effects on hepatic blood flow, may impair liver function and precipitate hepatic encephalopathy. We have therefore studied the effect of the beta b...

journal_title：Alimentary pharmacology & therapeutics

authors： Dunk AA,Moore J,Symon A,Dickie A,Sinclair TS,Mowat NA,Brunt PW

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:There is clear benefit from combination therapy with infliximab and immunosuppressive drugs (IS), but few data are available for adalimumab (ADA). AIM:To assess the efficacy of ADA monotherapy and ADA+IS for induction and maintenance therapy in Crohn's disease. METHODS:Retrospective study of patients with ...

journal_title：Alimentary pharmacology & therapeutics

authors： Reenaers C,Louis E,Belaiche J,Seidel L,Keshav S,Travis S

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection is a major cause of the progress of gastric glandular atrophy, a high-risk background factor in the development of gastric cancer. Regression of gastric atrophy is critical to prevention of cancer by H. pylori eradication treatment. However, it is controversial whether gastric a...

journal_title：Alimentary pharmacology & therapeutics

authors： Sugiyama T,Sakaki N,Kozawa H,Sato R,Fujioka T,Satoh K,Sugano K,Sekine H,Takagi A,Ajioka Y,Takizawa T,H. Pylori Forum Gastritis Study Group.

更新日期：2002-04-01 00:00:00

abstract：AIM:To appraise the tolerance and efficacy of an induction of tolerance protocol to infliximab permitting the re-administration of the drug to patients with Crohn's disease having had infusion reactions requiring suspension of treatment. METHODS:Fourteen patients were included in the induction of tolerance protocol. E...

journal_title：Alimentary pharmacology & therapeutics

authors： Duburque C,Lelong J,Iacob R,Seddik M,Desreumaux P,Fournier C,Wallaert B,Cortot A,Colombel JF

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Immunosuppressive therapy with azathioprine and mercaptopurine is commonly used in patients with various chronic diseases. The few existing data on the reproductive safety of these drugs after paternal use before conception are inconclusive. AIM:To examine the risk of congenital abnormalities in children fa...

journal_title：Alimentary pharmacology & therapeutics

authors： Nørgård B,Pedersen L,Jacobsen J,Rasmussen SN,Sørensen HT

更新日期：2004-03-15 00:00:00

abstract：BACKGROUND:Validated non-invasive measures of fatty liver are needed that can be applied across populations and over time. A fatty liver index (FLI) including body mass index, waist circumference, triglycerides and gamma glutamyltransferase (GGT) activity was developed in an Italian municipality, but has not been valid...

journal_title：Alimentary pharmacology & therapeutics

authors： Ruhl CE,Everhart JE

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Eosinophilic oesophagitis (EoE) has evolved from a supposedly rare entity to one whose incidence rates are approaching that of inflammatory bowel disease. The factors responsible for this apparent increase in the incidence remain obscure. AIM:To assess various endoscopist and pathologist factors that might ...

journal_title：Alimentary pharmacology & therapeutics

authors： Syed AA,Andrews CN,Shaffer E,Urbanski SJ,Beck P,Storr M

更新日期：2012-11-01 00:00:00