Abstract：
BACKGROUND:Pericardial effusion in uremic patients (UPE) was first described by R. Bright in 1836. It is generally agreed that patients require emergency pericardial drainage when tamponade signs are present, but in patients with no tamponade the optimal timing for drainage remains unclear. METHODS:To define patients who will require pericardial drainage, we retrospectively studied risk factors for pericardial drainage in patients admitted with pericardial effusion and chronic renal failure. RESULTS:Between 2000 and 2012, 44 UPE patients were identified using the database of our institution: 43% were under hemodialysis, 7% under peritoneal dialysis, 11% transplanted, 39% had chronic kidney disease (CKD) stage 4 or 5. Cause of UPE was uremic pericarditis in 45.5%, dialysis pericarditis in 45.5%, and other in 9%. On initial echocardiography, UPE was estimated small (<300 ml) in 38%, moderate (300-500 ml) in 32%, and large (>500 ml) in 30%. Tamponade signs were observed in 16% of patients. During follow-up, 100 % of large effusions required drainage (70% immediate, 30% delayed). For moderate and small UPE, the initial size on echocardiography was not discriminating. Serum albumin level was highly predictive of the risk of drainage: when albuminemia was ≤31 g/l, 35% patients were drained vs. only 7% when albuminemia was >31 g/l. CONCLUSION:In this first study reporting UPE drainage risk factors, all large UPE required drainage even when extra-renal epuration intensification or medical treatment were tried. This suggests that large UPE should be drained without delay. For small and moderate UPE, size of effusion on echocardiography does not predict drainage requirement but serum albumin level does.
journal_name
J Nephroljournal_title
Journal of nephrologyauthors
Bataille S,Brunet P,Decourt A,Bonnet G,Loundou A,Berland Y,Habib G,Vacher-Coponat Hdoi
10.1007/s40620-014-0107-7subject
Has Abstractpub_date
2015-02-01 00:00:00pages
97-104issue
1eissn
1121-8428issn
1724-6059journal_volume
28pub_type
杂志文章abstract：:Glomerulonephritis rarely appears associated with Hodgkin's disease or non-Hodgkin's lymphoma (NHL). We present a patient with a relapse of a non-Hodgkin's lymphoma which first presented as nephrotic syndrome due to focal segmental glomerulosclerosis (FSGS). This case report discusses the unusual association of non-Ho...
journal_title：Journal of nephrology
pub_type： 杂志文章
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更新日期：2007-09-01 00:00:00
abstract：:During Fabry disease, progressive glycosphingolipid deposition in the kidney causes gradual deterioration of renal function with proteinuria, uremia and hypertension. This results in end-stage renal disease (ESRD) which is one of the leading causes of morbidity and premature mortality in affected patients. Given the e...
journal_title：Journal of nephrology
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更新日期：2013-07-01 00:00:00
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journal_title：Journal of nephrology
pub_type： 杂志文章,评审
doi：
更新日期：2002-03-01 00:00:00
abstract：UNLABELLED:The prognosis of renal survival in both type 1 and type 2 diabetes mellitus is not benign. Several factors characterize the increase in the risk of developing renal damage in diabetic patients, distinguished in diabetes-related factors, genetic factors and other factors. DIAGNOSIS:Diagnosis requires standar...
journal_title：Journal of nephrology
pub_type： 杂志文章,评审
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更新日期：2003-07-01 00:00:00
abstract：:Patients with chronic kidney disease (CKD) have a greatly enhanced risk of cardiovascular morbidity and mortality. Over the past decade it has come clear that a disturbed calcium-phosphate metabolism, with Fibroblast Growth Factor-23 as a key hormone, is partly accountable for this enhanced risk. Numerous studies have...
journal_title：Journal of nephrology
pub_type： 杂志文章,评审
doi：10.1007/s40620-020-00715-2
更新日期：2020-06-01 00:00:00
abstract：:The combination of hypomagnesemia and hypocalciuria is the phenotypic signature of two distinct genetic renal tubular transport disorders: Gitelman's syndrome and autosomal dominant isolated renal magnesium wasting. In the past 5 years the genetic defects underlying these disorders have been elucidated through positio...
journal_title：Journal of nephrology
pub_type： 杂志文章,评审
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更新日期：2003-03-01 00:00:00
abstract：:A 17-year-old boy was admitted to the hospital twice in a year for 2 episodes of hemolytic uremic syndrome (HUS). During these 2 HUS episodes he had diarrhea, decreased serum complement, decreased total protein and decreased serum albumin concentrations. We suggest that protein-losing enteropathy and hypocomplementemi...
journal_title：Journal of nephrology
pub_type： 杂志文章
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更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:Adiponectin, a novel adipocytokine with antiinflammatory and antiatherosclerosis properties, has been found to be an inverse predictor of cardiovascular outcomes among uremic patients on hemodialysis. However, its role in uremic patients on continuous ambulatory peritoneal dialysis (CAPD) remains unclear. Th...
journal_title：Journal of nephrology
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：BACKGROUND:Oxidative stress plays a crucial role in chronic complications of diabetes such as diabetic nephropathy (DN), the main cause of renal failure. In diabetes, whether peroxynitrite (ONOO(-)), generated from inducible nitric oxide synthase (iNOS) induced by tumor necrosis factor alpha (TNF-alpha), plays a primar...
journal_title：Journal of nephrology
pub_type： 杂志文章
doi：
更新日期：2009-11-01 00:00:00
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journal_title：Journal of nephrology
pub_type： 杂志文章
doi：10.1007/s40620-018-0536-9
更新日期：2019-04-01 00:00:00
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journal_title：Journal of nephrology
pub_type： 杂志文章,多中心研究
doi：10.1007/s40620-015-0186-0
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Chronotropic incompetence (CI) is an independent predictor of cardiovascular events and overall mortality. The prevalence and significance of CI in renal transplant patient has not been examined. METHODS:38 non-heart failure renal transplant recipients were recruited for a transthoracic echocardiogram and t...
journal_title：Journal of nephrology
pub_type： 杂志文章
doi：10.1007/s40620-014-0091-y
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:This study investigated whether modifications of placental expression of endothelin-1 (ET-1), nitric oxide synthase (NOS) and tissue factor (TF) are associated with abnormal Doppler waveforms. METHODS:Fourteen pre-term severe preeclamptic (PE) women with fetal growth restriction (FGR) and 14 normal preg nan...
journal_title：Journal of nephrology
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:The pathogenesis of calcium-oxalate (CaOx) renal stones is still debated and a number of issues needs to be clarified. In particular, it is difficult to combine the intraluminal physical-chemical imbalance and fixed particle theory with the evidence that CaOx stones actually form and grow on Randall's plaque in the re...
journal_title：Journal of nephrology
pub_type： 杂志文章,评审
doi：
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:Left ventricular (LV) geometric patterns have never been evaluated as independent risk factors for renal disease progression (RDP). We investigated the risk factors for RDP in type 2 diabetic nephropathy patients, especially focusing on the effects of LV geometric patterns. METHODS:This was a single-center ...
journal_title：Journal of nephrology
pub_type： 杂志文章
doi：10.5301/jn.2010.353
更新日期：2011-01-01 00:00:00
abstract：INTRODUCTION:Several studies have suggested an effect of calcineurin inhibitors on arterial compliance in kidney transplant recipients. We aimed to investigate whether the type of calcineurin inhibitor influences large and small artery compliance in these patients independently of other determinants. METHODS:Patients ...
journal_title：Journal of nephrology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Von Hippel-Lindau (VHL) disease is a rare autosomal dominant disorder characterized by multifocal and bilateral renal cell carcinoma and cysts, retinal angiomas, hemangioblastoma of the central nervous system, pheochromocytoma, epididymis cystoadenoma, pancreatic cysts and/or islet cell tumors. However, phenotypic man...
journal_title：Journal of nephrology
pub_type： 杂志文章
doi：
更新日期：2005-03-01 00:00:00
abstract：:The relevance of the Salerno Medical School is examined through the contributions of Magister Maurus, Alfano I, Giovanni Plateario, Giovanni Afflacio, Bartolomeo and Urso of Calabria. An unpublished treatise on De Urinis in middlelatin and Italian volgare is introduced here for the first time by discussing the lapis o...
journal_title：Journal of nephrology
pub_type： 历史文章,杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：:Late-presenting end-stage renal disease is a significant problem worldwide. Up to 70% of patients start dialysis in an unplanned manner without a definitive dialysis access in place. Haemodialysis via a central venous catheter is the default modality for the majority of such patients, and peritoneal dialysis is usuall...
journal_title：Journal of nephrology
pub_type： 杂志文章,评审
doi：10.1007/s40620-018-0485-3
更新日期：2019-02-01 00:00:00
abstract：:Hemolytic uremic syndrome (HUS) is a rare disease characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. It is usually secondary to infections by strains of Escherichia coli (STEC) that produce Shiga-like toxin. In about 10% of patients, no STEC infections are reported. In these ...
journal_title：Journal of nephrology
pub_type： 杂志文章,评审
doi：10.5301/jn.5000146
更新日期：2012-11-01 00:00:00
abstract：:Primary renal non-Hodgkin's lymphoma is very rare in childhood. A six-year-old boy presented with bilateral non-obstructive multinodular nephromegaly and renal failure. Percutaneous needle biopsy showed large-cell lymphoma. The patient was started on chemotherapy. A right nephrectomy was done when systemic hypertensio...
journal_title：Journal of nephrology
pub_type： 杂志文章,评审
doi：
更新日期：2002-09-01 00:00:00
abstract：:Chyluria results from an abnormal connection between lymphatic bed and urinary tract, causing lymph leakage into the urine. The clinical picture often begins with the appearance of cloudy, milky urines accompanied by monolateral flank pain, malnutrition, weight loss and weakness. We report a case of chyluria that occu...
journal_title：Journal of nephrology
pub_type： 杂志文章
doi：10.5301/JN.2011.8355
更新日期：2011-09-01 00:00:00
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journal_title：Journal of nephrology
pub_type： 杂志文章
doi：10.1007/s40620-015-0212-2
更新日期：2016-02-01 00:00:00
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journal_title：Journal of nephrology
pub_type： 杂志文章
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更新日期：2005-11-01 00:00:00
abstract：QUESTIONS:- To what extent can ailing kidneys adapt their functions to the demands of pregnancy? - What risks is the nephropathic patient prone to throughout pregnancy compared with those of the general population, and which specific risks does her kidney disease determine? - What risks is the baby of a nephropathic pr...
journal_title：Journal of nephrology
pub_type： 杂志文章,评审
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更新日期：2006-03-01 00:00:00
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journal_title：Journal of nephrology
pub_type： 杂志文章
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更新日期：2016-06-01 00:00:00
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journal_title：Journal of nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s40620-016-0310-9
更新日期：2016-10-01 00:00:00
abstract：:Some patients with essential hypertension manifest increased urinary albumin excretion (UAE). Hypertensive patients with microalbuminuria manifest abnormal circadian variation of blood pressure, increased serum levels of LDL-cholesterol and lipoprotein(a), a greater rise of serum insulin in response to an oral glucose...
journal_title：Journal of nephrology
pub_type： 杂志文章,评审
doi：
更新日期：1997-07-01 00:00:00
abstract：BACKGROUND:Phosphate control is a crucial treatment goal in end-stage renal disease, but poor patient adherence to phosphate binder therapy remains a challenge. This study aimed to estimate the extent of phosphate binder adherence in hemodialysis patients and to identify potential determinants. METHODS:Phosphate binde...
journal_title：Journal of nephrology
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2014-12-01 00:00:00
abstract：:The metabolic syndrome is a cluster of cardiometabolic alterations at least partly dependent on reduced insulin sensitivity and hyperinsulinemia that can have several renal implications. A systematic review and meta-analysis of studies available in the international literature in English language demonstrates that the...
journal_title：Journal of nephrology
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s40620-014-0085-9
更新日期：2014-08-01 00:00:00
