Abstract：
:Kittens were deprived of clear vision in one eye only by +7D or -7D cylindrical lenses worn from eye opening until 7.5 months of age. Behavioral measurements subsequently demonstrated diminished acuity through the affected eye relative to the opposite control eye. However, single unit recordings at 3.5 years of age from retinal ganglion cells located within 1-11 degrees of the centre of the area centralis showed neither loss of grating resolution nor any abnormal orientation bias. Furthermore, the astigmatic rearing had minimal effect on the development of the cat's natural optics to the emmetropic state. The experiments indicate that the amblyopic defect induced by the cylindrical lenses occurs in the brain rather than the eye.
journal_name
Vision Resjournal_title
Vision researchauthors
Thibos LN,Levick WRdoi
10.1016/0042-6989(82)90165-1subject
Has Abstractpub_date
1982-01-01 00:00:00pages
43-53issue
1eissn
0042-6989issn
1878-5646pii
0042-6989(82)90165-1journal_volume
22pub_type
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