Abstract：
:The purpose of this prospective phase II/III trial was to study the effect of therapy intensification when combining procarbazine, lomustine, and vincristine (PCV) chemotherapy with a standard course of radiation therapy (RT) on cognitive functioning for patients with World Health Organization grade 2 low-grade gliomas (LGGs). Initial results of the trial demonstrated a progression-free survival benefit with adjuvant PCV, but no overall survival benefit in the intention-to-treat analysis. Because patients with LGGs have favorable prognostic indicators, the five-year overall survival rates range from 60%-70%. The effect of cancer treatment on neurocognitive function is a topic of increasing interest to healthcare providers and patients. The negative effect is commonly called "chemobrain" and refers to diminished concentration and compromised short-term memory following treatment. Chemobrain has been studied in other populations of patients with cancer (e.g., breast cancer) with associated statistically significant chemotherapy-associated compromised cognitive function when chemotherapy was added to RT.
journal_name
Oncol Nurs Forumjournal_title
Oncology nursing forumauthors
Behrend SWdoi
10.1188/14.ONF.335-336subject
Has Abstractpub_date
2014-05-01 00:00:00pages
335-6issue
3eissn
0190-535Xissn
1538-0688pii
B625L0836553H51Mjournal_volume
41pub_type
杂志文章,随机对照试验abstract：PURPOSE/OBJECTIVES:To evaluate the outcomes of hospice services and explore factors that affect the quality of life (QOL) of patients with cancer receiving hospice care. DESIGN:Descriptive. SETTING:Two homecare hospices in the southeastern United States. SAMPLE:Convenience sample of 118 hospice patients with a diagn...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To investigate the relationships among life stress, family functioning, family coping, reliance on formal and informal resources, and decisional conflict in cancer survivors. . DESIGN:Cross-sectional. . SETTING:Participants were recruited from the California Cancer Surveillance Program, hospital r...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/16.ONF.480-488
更新日期：2016-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To determine the degree to which nurses recognize levels of depressive symptoms in their patients with cancer and to describe patient characteristics that influence the accuracy of nurses' perceptions of depressive symptoms. DESIGN:Descriptive, prospective correlational design. SETTING:25 community...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To review issues regarding the use of genetic materials and information. DATA SOURCES:Professional literature, regional and federal legislation. DATA SYNTHESIS:An analysis is provided of the relationship among advances in genetic technology, use of genetic material and information, and the developm...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：2000-04-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To evaluate the effectiveness of ondansetron for the prevention of nausea and vomiting from dimethylsulfoxide (DMSO) during autologous stem cell transplantation (ASCT) infusion. DESIGN:Nonrandomized cohort using historical control. SETTING:Comprehensive cancer center outpatient infusion department....
journal_title：Oncology nursing forum
pub_type： 临床试验,杂志文章
doi：10.1188/13.ONF.285-292
更新日期：2013-05-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To describe the most current trends in quality-of-life (QOL) research in cervical cancer survivors and to discuss directions for future research. DATA SOURCES:A literature search was conducted among five electronic databases using the terms cervical or cervix cancer, quality of life, survivors, surv...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/11.ONF.E107-E117
更新日期：2011-03-01 00:00:00
abstract：:The COVID-19 crisis continues. Worldwide, there have been roughly 6.3 million cases and 380,000 deaths. In the United States, at the time of this writing, there were 106,200 deaths. As life has changed on many fronts, some predictable effects of the pandemic have occurred, including socioeconomic hardships, social iso...
journal_title：Oncology nursing forum
pub_type： 社论
doi：10.1188/20.ONF.371-372
更新日期：2020-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine the prevalence and severity of menopausal symptoms among breast cancer survivors and the relationship between menopausal symptoms and quality of life (QOL). DESIGN:Cross-sectional, descriptive. SETTING:Outpatient breast care center servicing a southeastern city and regional rural areas. ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To assess fear of progression (FoP) in outpatients with chronic myeloid leukemia (CML) on oral tyrosine kinase inhibitors (TKIs). DESIGN:Prospective and descriptive. SETTING:A university-based outpatient cancer clinic in Wuerzburg, Germany. SAMPLE:37 outpatients with CML on oral TKIs. . METH...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/16.ONF.190-197
更新日期：2016-03-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To determine predictors of fall events in hospitalized patients with cancer and develop a scoring system to predict fall events. DESIGN:Retrospective medical record review. SETTING:A 1,200-bed tertiary care hospital in northeastern Ohio. SAMPLE:145 patients with cancer who did not have a fall even...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/12.ONF.E407-E415
更新日期：2012-09-01 00:00:00
abstract：:Hemochromatosis results when the body's iron stores progressively increase. Surplus iron stored in body tissues leads to organ dysfunction and death. Warnings that elevated iron stores increase the risk of cancer development necessitate a review of this condition. Two types of hemochromatosis, hereditary and secondary...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：1992-10-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To explore the experience of being touched in people diagnosed with cancer and undergoing IV chemotherapy. RESEARCH APPROACH:Qualitative, phenomenologic. SETTING:Central New York and northern Pennsylvania, both in the northeastern United States . PARTICIPANTS:11 Caucasian, English-speaking adult...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/15.ONF.517-526
更新日期：2015-09-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To test body-related shame and guilt as predictors of breast cancer survivors' (BCS') moderate to vigorous intensity physical activity (MVPA) during six months and to examine motivational regulations as mediators of this association. . DESIGN:Prospective study. . SETTING:Survivors were recruited th...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/17.ONF.465-475
更新日期：2017-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine empirical research regarding the role of malglycemia (hyperglycemia, hypoglycemia, or glycemic variability) on clinical outcomes among hospitalized patients with cancer. DATA SOURCES:Research articles were obtained from the Ovid, PubMed, and CINAHL® databases. Key words used in the search...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/12.ONF.458-465
更新日期：2012-09-01 00:00:00
abstract：:The influence of fluid intake and hydration rate on the frequency of vomiting was evaluated during 254 outpatient cisplatin infusions administered to 60 patients. The basic antiemetic regimen was consistent and used metoclopramide hydrochloride (Reglan) 2 mg/kg/dose (means = 150 mg) starting 30 minutes before cisplati...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To review nursing assessment and implications of oral complications from cancer therapy. DATA SOURCES:Published articles, books, and monographs. DATA SYNTHESIS:Cancer and cancer therapy disturb the normal integrity and function of the oral cavity, leading to alterations in structure and function. S...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To describe nighttime sleep-wake patterns during a 12-hour night shift among school-age children with cancer receiving inpatient chemotherapy and relationships among nighttime sleep, environmental stimuli, medication doses, and symptoms during that shift. DESIGN:Exploratory, descriptive, multiple-ca...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/12.ONF.553-561
更新日期：2012-11-01 00:00:00
abstract：PROBLEM IDENTIFICATION:Poor health outcomes have been associated with hyperglycemia in patients with and without diabetes. However, the impact of hyperglycemia on the health-related outcomes of patients with cancer has shown conflicting results. The purpose of this review was to explore definitions and measurement issu...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/17.ONF.E141-E151
更新日期：2017-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To describe the planning, implementation, and evaluation of an educational program to increase the awareness of cancer clinical trials among community-dwelling seniors in a southeastern metropolitan community. DATA SOURCES:Published articles, research findings, conference proceedings, government-iss...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/03.ONF.E80-E83
更新日期：2003-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To explore the topic of moral distress in nurses related to witnessing futile care. DATA SOURCES:Literature related to moral distress and futility; analysis of narratives written by 108 nurses attending one of two national continuing education courses on end-of-life care regarding their experiences ...
journal_title：Oncology nursing forum
pub_type： 杂志文章,评审
doi：10.1188/06.ONF.922-930
更新日期：2006-09-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine early symptom and diagnostic-seeking experiences of women newly diagnosed with ovarian cancer. DESIGN:Longitudinal descriptive. SETTING:Homes of families. SAMPLE:Purposive; 19 families were obtained by referrals. METHODS:Interviews and questionnaires; descriptive analysis. MAIN RESEAR...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/03.ONF.927-933
更新日期：2003-11-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To obtain experiential data regarding African American older adult survivors' perceptions of and recommendations on the role of community health workers (CHWs) in providing a cancer navigation intervention. RESEARCH APPROACH:Focus groups. SETTING:Rural Virginia and urban Maryland. PARTICIPANTS:48 ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/12.ONF.E288-E298
更新日期：2012-05-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To examine relationships between coping resources and self-rated health among Latina breast cancer survivors. DESIGN:Cross-sectional telephone survey. SETTING:Four northern California counties. SAMPLE:330 Latina breast cancer survivors within one to five years of diagnosis. METHODS:Telephone surv...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/11.ONF.523-531
更新日期：2011-09-01 00:00:00
abstract：:Little is known about how/why women who receive adjuvant chemotherapy treatment, hormone therapy, or radiation for nonmetastatic breast cancer gain weight. This study's purpose was to use the restraint-disinhibition model to understand susceptibility to weight gain, and the potential impact of exercise and dysphoria. ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To determine the effect of aerobic and strength resistance training and epoetin alfa (EPO) therapy on transfusions, stem cell collections, transplantation recovery, and multiple myeloma treatment response. DESIGN:Randomized clinical trial. SETTING:A myeloma research and therapy center in the south ...
journal_title：Oncology nursing forum
pub_type： 杂志文章,随机对照试验
doi：10.1188/08.ONF.E53-E61
更新日期：2008-05-01 00:00:00
abstract：:The oncology nursing specialty seeks to reduce the risks, incidence, and burden of cancer by encouraging healthy lifestyles, promoting early detection, improving the management of cancer symptoms and side effects throughout the disease trajectory, and leading the coordination of complex care needs. ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/20.ONF.125-126
更新日期：2020-03-01 00:00:00
abstract：:Continuous infusion therapy (CIT) is an alternative to traditional intravenous bolus or brief infusion chemotherapy. The benefits of CIT are improved therapeutic index, reduced toxicity, and modification of drug resistance. CIT administered in the ambulatory setting fosters cost effectiveness and improved patient sati...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：PURPOSE/OBJECTIVES:To explore patients' quality of life (QOL) as defined by RNs in adult and pediatric oncology settings and to examine, from the perspectives of clinical nurses, the knowledge that is needed to apply QOL research outcomes in clinical practice. DESIGN:Qualitative research design using a focus group tec...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/02.ONF.E118-E126
更新日期：2002-11-01 00:00:00
abstract：Purpose/Objectives:To describe and compare survivors' and providers' views of the uses of and perceived benefits and drawbacks of survivor self-advocacy. Design:A cross-sectional, two-group, mixed-methods survey. Setting:Survivors were recruited from local and national registries and advocacy organizations. Providers...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/17.ONF.52-59
更新日期：2017-01-03 00:00:00
abstract：PURPOSE/OBJECTIVES:To measure the association between physical activity and social cognitive theory constructs during breast cancer treatment. DESIGN:Cross-sectional survey. SETTING:Midwestern, academic oncology clinic. SAMPLE:21 primarily Caucasian (90%) female patients with breast cancer undergoing treatment. 76% ...
journal_title：Oncology nursing forum
pub_type： 杂志文章
doi：10.1188/05.ONF.807-815
更新日期：2005-07-01 00:00:00
