Abstract：
:Cannabichromene (CBC) is one of four major cannabinoids in Cannabis sativa L. and is the second most abundant cannabinoid in drug-type cannabis. Cannabichromene and some of its homologs, analogs, and isomers were evaluated for antiinflammatory, antibacterial, and antifungal activity. Antiinflammatory activity was evaluated by the carrageenan-induced rat paw edema and the erythrocyte membrane stabilization method. In both tests, CBC was superior to phenylbutazone. Antibacterial activity of CBC and its isomers and homologs was evaluated using gram-positive, gram-negative, and acid-fast bacteria. Antifungal activity was evaluated using yeast-like and filamentous fungi and a dermatophyte. Antibacterial activity was strong, and the antifungal activity was mild to moderate.
journal_name
J Clin Pharmacoljournal_title
Journal of clinical pharmacologyauthors
Turner CE,Elsohly MAdoi
10.1002/j.1552-4604.1981.tb02606.xsubject
Has Abstractpub_date
1981-08-01 00:00:00pages
283S-291Sissue
S1eissn
0091-2700issn
1552-4604journal_volume
21pub_type
杂志文章abstract：:In vitro data on the metabolism of the antifungal voriconazole suggest that its pharmacokinetics might be influenced by the activity of CYP2C19, CYP2C9, and CYP3A. To elucidate the genetic influence of polymorphic enzymes on voriconazole metabolism, the authors pooled the pharmacokinetic data from 2 interaction studie...
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pub_type： 临床试验,杂志文章,随机对照试验
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doi：10.1002/j.1552-4604.1979.tb01613.x
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journal_title：Journal of clinical pharmacology
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journal_title：Journal of clinical pharmacology
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journal_title：Journal of clinical pharmacology
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journal_title：Journal of clinical pharmacology
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journal_title：Journal of clinical pharmacology
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doi：
更新日期：2000-12-01 00:00:00
