Near infrared spectroscopy: methodological principles and clinical application in preterm infants.

Abstract:

:Neonatal encephalopathy, plausibly related to hypoxia and ischaemia, remains one of the main problems in perinatal medicine. Efforts are necessary to find new non-invasive methods for assessing brain oxygenation. Near infrared spectroscopy (NIRS) provides information on the concentrations of the oxygenated and deoxygenated forms of haemoglobin, as well as of the redox state of cytochrome aa3. Different important variables such as cerebral blood volume and flow, and the responses of these to changes in pCO2, can be derived through haemoglobin measurement. Changes in cytochrome aa3 may provide immediate information on intracellular oxygen utilization. Various studies have shown the feasibility of NIRS in preterm infants. Methodological and technical problems of this method are discussed.

journal_name

Wien Klin Wochenschr

authors

Bernert G,von Siebenthal K,Kohlhauser C,Casaer P

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

569-73

issue

19

eissn

0043-5325

issn

1613-7671

journal_volume

107

pub_type

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