The use of recombinant human erythropoietin in lung transplantation.

Abstract:

:Recombinant human erythropoietin (r-HuEPO) was administered in 4 lung transplant recipients to treat chronic anemia beyond the immediate postoperative period. There were 2 males and 2 females with a mean age of 38 years (range 22-49). None of the patients had major infection or rejection problems, and no blood products were used. Because of different individual responses duration of therapy was 1 to 17 weeks (median 5) with a total dosage ranging from 8 to 36 x 10(3) IU (mean 21 x 10(3)). The median single dose was 58 IU/kg (range 36-100). Hemoglobin levels increased significantly from 9.1 +/- 0.2 to 12.7 +/- 0.3 g/dl (mean +/- SE; p < 0.01). There were no side effects. r-HuEPO is recommended in treatment of chronic anemia in lung transplant patients to save blood products and to exclude the potential risk of transfusion-transmitted viral infections.

journal_name

Wien Klin Wochenschr

authors

End A,Stift A,Ringl H,Inhauser T,Grimm M,Geissler K,Stockenhuber F,Klepetko W

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

181-3

issue

6

eissn

0043-5325

issn

1613-7671

journal_volume

107

pub_type

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