Abstract:
PURPOSE:To evaluate duplex Doppler sonography to assess renal vascular resistance (RVR) in diabetic patients. MATERIALS AND METHODS:Resistive indexes (RIs) and pulsatility indexes (PIs) were measured in intrarenal arteries of 144 patients with diabetes mellitus and 61 control subjects. RIs and PIs were compared for control subjects and patients with diabetic nephropathy and correlated with laboratory and clinical findings. RESULTS:In control subjects, the mean RI was 0.595 +/- 0.033 (standard deviation) and mean PI was 1.001 +/- 0.105. Elevated RIs and PIs accompanied progression of nephropathy. Statistically significant (P < .001) correlations were observed between both RI and PI and serum creatinine level, creatinine clearance rate, systolic and diastolic blood pressure measurements, and patient age. CONCLUSION:Doppler indexes reflect increased RVR in diabetic nephropathy and correlate with laboratory and clinical parameters, but RI and PI measurements offer no advantages over these parameters to predict disease progress or in patient care.
journal_name
Radiologyjournal_title
Radiologyauthors
Brkljacić B,Mrzljak V,Drinković I,Soldo D,Sabljar-Matovinović M,Hebrang Adoi
10.1148/radiology.192.2.8029430subject
Has Abstractpub_date
1994-08-01 00:00:00pages
549-54issue
2eissn
0033-8419issn
1527-1315journal_volume
192pub_type
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