Abstract:
OBJECTIVE:To compare, in pregnant women, the endocervical cell yield of the Cytobrush Cell Collector and the Cervex-Brush Cell Sampler with the standard cotton swab, and to determine the incidence of serious adverse events associated with the collection techniques. METHODS:In a randomized, controlled clinical trial, 352 pregnant women undergoing initial obstetric evaluation were randomly assigned to either the cotton swab and modified Ayers spatula, Cytobrush and modified Ayers spatula, or Cervex-Brush. The cytopathology laboratory, blinded to the Papanicolaou smear method, screened the smears using the Bethesda System guidelines. Statistical analyses were performed using the Pearson chi 2 and analysis of variance tests. RESULTS:There was an increased detection of endocervical cells in pregnant patients with both the Cytobrush and modified Ayers spatula (90.7%) and the Cervex-Brush (83.3%) methods, compared with the cotton swab and modified Ayers spatula (70.8%) (P = .0001 and P = .0233, respectively). There was no statistically significant difference between the Cytobrush-spatula and Cervex-Brush groups (P = .0956). Although there were more bloody Papanicolaou smears in the study groups, this was neither clinically nor statistically significant because all the samples were interpretable and repeat samples due to bloody specimens were not required. There were no serious adverse events associated with the study group methods. CONCLUSION:Performance of Papanicolaou smears using the Cytobrush and modified Ayers spatula and with the Cervex-Brush improved Papanicolaou smear adequacy as compared with the cotton swab and modified Ayers spatula. Despite an increased incidence of spotting following collection, these techniques were not associated with an increase in serious adverse events. Based on the cost per item and a clinically significant increase in endocervical cell yield, we recommend the Cytobrush and modified Ayers spatula for cytologic screening in pregnant women.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Paraiso MF,Brady K,Helmchen R,Roat TWsubject
Has Abstractpub_date
1994-10-01 00:00:00pages
539-43issue
4eissn
0029-7844issn
1873-233Xjournal_volume
84pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVE:To determine whether high levels of serum alpha-fetoprotein (AFP) predict increased risk of adverse pregnancy outcomes, including preterm birth (before 37 weeks), preterm birth occurring at or before 28 weeks, small for gestational age (SGA) infant, preeclampsia, and placental abnormalities, and to determine ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0029-7844(96)00310-9
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:To describe the presenting symptoms of women with depression in two obstetrics and gynecology clinics, determine depression diagnosis frequency, and examine factors associated with depression diagnosis. METHODS:Data were extracted from charts of women screening positive for depression in a clinical trial tes...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e31829999ee
更新日期:2013-08-01 00:00:00
abstract::The weights of 101 neonates delivered within 72 hours of real-time ultrasound examination were compared with the weight calculated from the ultrasonically measured biparietal diameter and abdominal circumference. A high degree of correlation (4 = .9624) was found between actual and calculated weights. This method of w...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1981-06-01 00:00:00
abstract:OBJECTIVE:To evaluate amniotic fluid arachidonic acid metabolites using enzymatic and nonenzymatic (lipid peroxidation) pathways in spontaneous preterm birth and term births, and to estimate whether prostanoid concentrations correlate with risk factors (race, cigarette smoking, and microbial invasion of amniotic cavity...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e3182204eaa
更新日期:2011-07-01 00:00:00
abstract::Twenty nonpregnant women with condylomata acuminata of the vagina were studied to assess the effectiveness of weekly topical 5-fluorouracil application. All patients were instructed to insert an applicator one-third full of 5% 5-fluorouracil cream (approximately 1.5 g) deeply into the vagina at bedtime once each week ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1987-07-01 00:00:00
abstract::Nitrous oxide analgesia was introduced into obstetrics by a young Polish-Russian physician who manufactured the gas himself, mixed it with oxygen, humidified the mixture with water vapor, and devised a mouthpiece for self-administration. After assessing the results on himself, he evaluated the effects on pain relief, ...
journal_title:Obstetrics and gynecology
pub_type: 历史文章,杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract::Serum measurements of beta-human chorionic gonadotropin (beta-hCG) for pregnancy tests are now positive at very low levels (25 mIU/mL). Sonography is the diagnostic method of choice for patients with the possibility of intrauterine trophoblastic disease. A case is reported in which ultrasound confused an ovarian neopl...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/00006250-198603001-00027
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVE:To identify facilitators of and barriers to pregnant women being vaccinated against seasonal influenza by identifying factors associated with influenza vaccination during pregnancy among women who had recently given birth to a live infant. METHODS:We analyzed pooled data from Georgia (n=2,692) and Rhode Isla...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e3181f1039f
更新日期:2010-10-01 00:00:00
abstract::Two hundred women were studied in a randomized controlled trial of induction of labor using high-dose (3 mg) or low-dose (0.5 mg) prostaglandin E2 vaginal pessaries. Induction using 3-mg pessaries was more successful, with a shorter overall induction-delivery interval and less requirement for analgesia, although uteri...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章
doi:
更新日期:1984-03-01 00:00:00
abstract:OBJECTIVE:To quantify physician prescribing patterns and patient opioid use in the 2 weeks after hysterectomy at an academic institution and to determine whether patient factors predict postsurgical opioid use and pain recovery. METHODS:We conducted a prospective quality initiative study by recruiting all English-spea...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000002344
更新日期:2017-12-01 00:00:00
abstract::This month we focus on current research in maternal heart disease. Dr. Metz discusses four recent publications, which are concluded with a "bottom-line" that is the take-home message. A complete reference for each can be found on on this page along with direct links to abstracts. ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000003037
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy and safety of an oral formulation of tranexamic acid for the treatment of heavy menstrual bleeding. METHODS:Adult women with heavy menstrual bleeding (mean menstrual blood loss 80 mL or more per cycle) were enrolled in a double-blind, placebo-controlled study. After two pretreatment me...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/AOG.0b013e3181f20177
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To compare one-year outcomes of primary overlap versus end-to-end repair of the external anal sphincter after acute obstetric anal sphincter injury. METHODS:Women who sustained third-degree (3b = greater than 50% external anal sphincter thickness, 3c = internal sphincter injury) or fourth-degree (including a...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.AOG.0000218693.24144.bd
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy and safety of titrated oral misoprostol and vaginal misoprostol for labor induction. METHODS:Women between 34 and 42 weeks of gestation with an unfavorable cervix (Bishop score less than or equal to 6) and an indication for labor induction were randomLy assigned to receive titrated or...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.AOG.0000297313.68644.71
更新日期:2008-01-01 00:00:00
abstract::The effect on labor of administering ritodrine after a premature rupture of the membranes (PROM) was studied in a double-blind trial in 30 patients. The patients were selected according to the following criteria: 28 to 36 weeks' gestation, only 1 fetus, cervix dilated 4 cm or less, and absence of pyrexia or other sign...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章
doi:
更新日期:1980-02-01 00:00:00
abstract::Two hundred sixty-four consecutive patients with clinical stage I endometrial adenocarcinoma who underwent primary surgical therapy between July 1979 and August 1988 were followed prospectively and evaluated for disease recurrence for 8-112 months (mean 51.5). Thirty-three patients (12.5%) developed recurrence or died...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::Real time ultrasonographic examination of the fetal perineal area after 30 weeks of gestation can reveal the external genitalia of the male fetus. The absence of this finding indicates a female fetus. This assessment is possible in up to two-thirds of cases, being limited only by the fetal presentation, position, and ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1977-10-01 00:00:00
abstract::Infertility is a disease that affects up to 15.5% of reproductive-aged couples. Until the birth of the first neonate born from in vitro fertilization (IVF) in 1978, many infertile couples did not have an opportunity to conceive a biological child. Over the past 40 years, access to and effectiveness of IVF have increas...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1097/AOG.0000000000002786
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:Despite a change of fetal physiologic and biochemical functions with gestational age, stationary umbilical cord acid-base reference values are used as measures of obstetric care quality. The aim of this study was to assess the risk of low Apgar score relative to low pH when using stationary versus gestational...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(03)00512-x
更新日期:2003-08-01 00:00:00
abstract::There is growing recognition of the importance and potential benefit of information technology and electronic medical records in providing quality care for women. Incorporation of obstetrician-gynecologist-specific requirements by electronic medical record vendors is essential to achieve appropriate electronic medical...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e3181e1328c
更新日期:2010-07-01 00:00:00
abstract::There is well-known difficulty in controlling hemorrhage from presacral vessels. There are reports on the use of thumbtacks to secure hemostasis in the face of presacral hemorrhage. This communication reports the successful use of thumbtacks to establish presacral hemostasis and describes a simple instrument designed ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1991-08-01 00:00:00
abstract::In a comparative trial, ethanol effectively arrested preterm labor for 48 hours for more in 32% of cases, a beta-adrenergic agent (salbutamol) in 60% of cases (not statistically significant), and a combination of ethanol and indomethacin in 70% of cases (statistically significant, P less than 0.5). Labor was delayed f...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1979-02-01 00:00:00
abstract::The hospital-based alternative birth room has become a popular alternative to the conventional labor and delivery room setting. Responses to a mailed questionnaire from 78 of 82 (95%) Washington State hospitals with obstetric services were used to relate available birth options to alternative birth room status and obs...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1981-11-01 00:00:00
abstract::A new analog of luteinizing-hormone-releasing factor, (Des-Gly-NH-2-10, Pro-ethylamide-9)-LHRF, was tested in healthy women with regular menstrual cycles. This synthetic nonapeptide amide was injected intravenously in a dose of 200 mug into 15 normal female volunteers in the follicular, preovulatory, and luteal phases...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::Sixty-two patients with primary amenorrhea were retrospectively categorized into 4 groups: 1) breast development absent and uterus present (29 patients), 2) breast development present and uterus absent (9 patients), 3) both breast development and uterus absent (2 patients), and 4) both breast development and uterus pr...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1981-06-01 00:00:00
abstract::One thousand twenty inductions of labor by amniotomy and continuous infusion of oxytocin at the Royal Women's Hospital were reviewed. Three different starting rates of infusion of oxytocin were used by altering the concentration to 2, 5, or 10 U/L. There was no difference in success of induction as measured by inducti...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::A rabbit serum fraction was prepared which contained antibody specific for unique antigen(s) found in human condylomata acuminata tissue but not in other human papillomatous or normal tissues. Indirect immunofluorescent staining of cryostat sections of human tissues demonstrated an intense nuclear fluorescence in cell...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1981-03-01 00:00:00
abstract::Two hundred thirty-three cases of endometrial carcinoma were analyzed for DNA content using flow cytometry of cell nuclei extracted from archival paraffin blocks. The median follow-up time for the cases was 8.7 years. Aneuploidy, present in 18% of tumors overall, was associated with adverse histologic type, high grade...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract::Women who do not have a documented germline mutation or who do not have a strong family history suspicious for a germline mutation are considered to be at average risk of ovarian cancer. Women who have confirmed deleterious BRCA1 and BRCA2 germline mutations are high risk of ovarian cancer. In addition, women who have...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1097/AOG.0b013e3181ec5fc1
更新日期:2010-09-01 00:00:00
abstract::Reported is a rare complication of radical hysterectomy and radiation therapy, recurrent streptococcal cellulitis. Two patients had 14 episodes over a nine-year period, characterized by high fever and systemic toxicity. The streptococcal cellulitis was atypical in its presentation and its causative organism. The rash ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1984-06-01 00:00:00