Chronic diffuse infiltrative lung disease: determination of the diagnostic value of clinical data, chest radiography, and CT and Bayesian analysis.

Abstract:

PURPOSE:To assess the value of clinical, chest radiographic, and computed tomographic (CT) findings in classifying chronic diffuse infiltrative lung disease (CDILD) MATERIALS AND METHODS: Two samples from the same population were consecutively studied: the training set (group A, n = 208) for the development of the decision aid and the test set (group B, n = 100) for validation. Computer-aided diagnoses were made with a Bayesian model that assigned to each patient diagnostic probabilities based on clinical, radiographic, or CT variables. RESULTS:In group A, a correct diagnosis based on clinical data was obtained in 29% of cases; radiography, 9%; and CT, 36%. This increased to 54% when clinical and radiographic variables were combined (P < .0001) and to 80% when data from all three were analyzed together (P < .0001). With prior and conditional probabilities determined from group A, the frequency of correct diagnosis in group B was 27% with clinical data, which increased to 53% (P < .0001) with radiographic findings and 61% after including CT data (P = .07). CONCLUSION:CT can help determine the specific diagnosis in patients with CDILD.

journal_name

Radiology

journal_title

Radiology

authors

Grenier P,Chevret S,Beigelman C,Brauner MW,Chastang C,Valeyre D

doi

10.1148/radiology.191.2.8153310

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

383-90

issue

2

eissn

0033-8419

issn

1527-1315

journal_volume

191

pub_type

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