Acetylcholinesterase and choline acetyltransferase localization patterns do correspond in cat and rat retinas.

Abstract:

:Is acetylcholinesterase (AChE) a reliable marker for cholinergic activity in the cat and rat retinas? To evaluate this question, radial sections, labeled for AChE, have been compared to sections labeled for choline acetyltransferase (ChAT). Within the inner plexiform layer (IPL) of each species, two lightly-stained AChE bands are revealed which correspond to the depths of ChAT immunoreactivity. Although retinal AChE is not limited exclusively to sites where ChAT is present, AChE and ChAT activity do occur in the same IPL sublaminae. Used with proper caution, AChE is a reliable secondary indicator of cholinergic activity.

journal_name

Vision Res

journal_title

Vision research

authors

Criswell MH,Brandon C

doi

10.1016/0042-6989(93)90165-s

subject

Has Abstract

pub_date

1993-09-01 00:00:00

pages

1747-53

issue

13

eissn

0042-6989

issn

1878-5646

pii

0042-6989(93)90165-S

journal_volume

33

pub_type

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