Abstract:
:The anticholinergic and antispasmodic activity of atropine, propantheline, imipramine, and flavoxate were judged by each drug's ability to inhibit bethanechol chloride and barium chloride-induced canine detrusor contractions. In this in vitro model, atropine and propantheline are pure anticholinergic agents. Imipramine significantly decreases both bethanechol and barium-induced contractions, while flavoxate only minimally inhibits the response to either stimulant.
journal_name
Urologyjournal_title
Urologyauthors
Benson GS,Sarshik SA,Raezer DM,Wein AJdoi
10.1016/0090-4295(77)90279-5subject
Has Abstractpub_date
1977-01-01 00:00:00pages
31-5issue
1eissn
0090-4295issn
1527-9995journal_volume
9pub_type
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