Growth and differentiation of human papillomavirus type 31b positive human cervical cell lines.

abstract：BACKGROUND:Although overall cervical cancer incidence rates have decreased in both black and white women in the U.S. since the mid 1950s due to widespread screening, rates continue to be higher among blacks than among whites. However, whether this pattern differs by age is unknown. METHODS:Cervical cancer cases (1975-...

journal_title：Gynecologic oncology

authors： Simard EP,Naishadham D,Saslow D,Jemal A

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:Molecular markers associated with tumor progression in uterine carcinoma are poorly defined. In this study, we determine whether upregulation of LAMC1, a gene encoding extracellular matrix protein, laminin γ1, is associated with various uterine carcinoma subtypes and stages of tumor progression. METHODS:An ...

journal_title：Gynecologic oncology

authors： Kashima H,Wu RC,Wang Y,Sinno AK,Miyamoto T,Shiozawa T,Wang TL,Fader AN,Shih IeM

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Although the antiproliferative and differentiating properties of vitamin D have been demonstrated, its effects on cancer cells are variable. Little is known about vitamin D receptor (VDR) levels in patients with ovarian cancer. In this population we sought to determine correlations between VDR expression, cli...

journal_title：Gynecologic oncology

authors： Silvagno F,Poma CB,Realmuto C,Ravarino N,Ramella A,Santoro N,D'Amelio P,Fuso L,Pescarmona G,Zola P

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Small cell carcinoma (SmCC) of the female genital tract constitutes a diagnostic and clinical challenge given its rarity and the lack of standardized therapeutic approaches. Here we review the morphological, clinical and molecular features of gynecologic SmCCs and discuss potential areas for future research. ...

journal_title：Gynecologic oncology

authors： Atienza-Amores M,Guerini-Rocco E,Soslow RA,Park KJ,Weigelt B

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine whether para-aortic lymphadenectomy improves disease-related survival (DRS) in stage IIIc endometrial cancer. METHODS:A total of 63 patients with stage IIIc endometrial carcinoma underwent primary radical surgery in the Tohoku Gynecologic Cancer Unit from 1993 to 20...

journal_title：Gynecologic oncology

authors： Fujimoto T,Nanjyo H,Nakamura A,Yokoyama Y,Takano T,Shoji T,Nakahara K,Yamada H,Mizunuma H,Yaegashi N,Sugiyama T,Kurachi H,Sato A,Tanaka T

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:The 2018 International Federation of Gynecology and Obstetrics (FIGO) staging system for cervical cancer changed from a clinical system to a clinical/pathologic/radiologic system with stages IIIC1 and IIIC2 indicating positive pelvic and para-aortic lymph nodes, respectively. We evaluated the National Cancer ...

journal_title：Gynecologic oncology

authors： McComas KN,Torgeson AM,Ager BJ,Hellekson C,Burt LM,Maurer KA,Werner TL,Gaffney DK

更新日期：2020-01-01 00:00:00

abstract：:Two patients with resistant gestational choriocarcinoma were treated w with Taxol after extensive prior chemotherapy including EMACO and platinum-based salvage chemotherapy. Both patients showed significant responses to Taxol. One patient relapsed in the brain and liver after treatment and died. Taxol was combined wit...

journal_title：Gynecologic oncology

authors： Jones WB,Schneider J,Shapiro F,Lewis JL Jr

更新日期：1996-04-01 00:00:00

abstract：:One hundred and fifty-six patients with cervical intraepithelial neoplasia (CIN) were treated with CO2 laser and followed for 2 1/2 to 6 years. There were 19 recurrences, of which 14 occurred in patients treated with a power density of less than 1000 W/cm2 to a depth of 6 mm. All of the recurrences were subjected to a...

journal_title：Gynecologic oncology

authors： Caglar H,Ayhan A,Hreshchyshyn MM

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:Patients who develop recurrent ovarian of fallopian tube carcinoma involving the liver often have disease refractory to chemotherapy and carry a poor prognosis. The impact of aggressive resection in this patient population is unclear. METHODS:From 1/1988 to 9/2001, 24 patients with recurrent ovarian or fall...

journal_title：Gynecologic oncology

authors： Yoon SS,Jarnagin WR,Fong Y,DeMatteo RP,Barakat RR,Blumgart LH,Chi DS

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:The present study was planned to measure preoperative levels of soluble urokinase plasminogen activator receptor (suPAR) in plasma from patients with gynecological diseases, and to test for a relationship to clinical and biochemical patient characteristics. METHODS:Using a specific and sensitive kinetic ELIS...

journal_title：Gynecologic oncology

authors： Riisbro R,Stephens RW,Brünner N,Christensen IJ,Nielsen HJ,Heilmann L,von Tempelhoff GF

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:Self-collected HPV testing could substantially reduce disparities in cervical cancer screening, with slightly lower sensitivity compared to physician-collected specimens cross-sectionally. We aimed to evaluate the comprehensive long-term performance of self-collected HPV testing prospectively. METHODS:In 199...

journal_title：Gynecologic oncology

authors： Zhang L,Xu XQ,Hu SY,Chen F,Zhang X,Pan QJ,Zhang WH,Feng RM,Dong L,Zhang Q,Ma JF,Sauvaget C,Zhao FH,Qiao YL,Sankaranarayanan R

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Vulval Keratoacanthoma (KA) is very rare and its differential diagnosis from the commonly occurring Vulval Squamous Cell Carcinoma (SCC) is important to avoid overtreatment. CASE:A case of Vulval KA in a 79-year-old lady is reported. She presented with a 9-mm firm raised lesion on the antero-lateral left si...

journal_title：Gynecologic oncology

authors： Nascimento MC,Cominos D,Davies NJ,Obermair A

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:About 30% of Adult type granulosa cell tumors of the ovary (AGCTs) are diagnosed in fertile age. In stage I, conservative surgery (fertility-sparing surgery, FSS), either unilateral salpingo-oophorectomy (USO) or cystectomy are possible options. The aim of this study is to compare oncological outcomes of FSS ...

journal_title：Gynecologic oncology

authors： Bergamini A,Cormio G,Ferrandina G,Lorusso D,Giorda G,Scarfone G,Bocciolone L,Raspagliesi F,Tateo S,Cassani C,Savarese A,Breda E,De Giorgi U,Mascilini F,Candiani M,Kardhashi A,Biglia N,Perrone AM,Pignata S,Mangili G

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:While primary cisplatin-based intraperitoneal chemotherapy has been shown to favorably impact survival in small-volume residual advanced ovarian cancer, there is a need to develop strategies that improve the effectiveness of this approach. METHODS:A multi-center phase 2 trial was conducted that added intrave...

journal_title：Gynecologic oncology

authors： Smith HO,Moon J,Wilczynski SP,Tiersten AD,Hannigan EV,Robinson WR,Rivkin SE,Anderson GL,Liu PY,Markman M

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to compare survival outcomes of total abdominal radical hysterectomy (TARH) versus laparoscopy-assisted radical vaginal hysterectomy (LARVH) in stage IA2-IB2 cervical cancer. METHODS:812 patients who underwent RH between 2008 and 2017 were evaluated in 3 institutions. Progression-free...

journal_title：Gynecologic oncology

authors： Kwon BS,Roh HJ,Lee S,Yang J,Song YJ,Lee SH,Kim KH,Suh DS

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To assess the treatment and outcome of patients with endometrial cancer following isolated pulmonary relapse. METHODS:Between 1984 and 1996, 82 of 1109 patients undergoing surgery for primary endometrial cancer experienced a primary pulmonary recurrence, 28 of which were solitary. Median follow up of censore...

journal_title：Gynecologic oncology

authors： Dowdy SC,Mariani A,Bakkum JN,Cliby WA,Keeney GL,Podratz KC

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:Although many clinicians practice empiric dose reduction to prevent toxicity, it is unknown whether obese patients given chemotherapy dosed according to actual body weight (ABW) experience excess toxicity. At our institution, cancer patients receive chemotherapy dosed by ABW unless on a protocol capping dose...

journal_title：Gynecologic oncology

authors： Schwartz J,Toste B,Dizon DS

更新日期：2009-07-01 00:00:00

abstract：:From November 1983 to October 1992, 22 patients with invasive cervical cancer stage IB through stage IIIB with metastasis to para-aortic nodes were entered in this study. Five patients were excluded. Of 17 remaining evaluable patients, 5 (29%) were stage IB, 6 (35%) were stage IIB, and 6 (35%) were stage IIIB. Four (2...

journal_title：Gynecologic oncology

authors： Husseinzadeh N,Shrake P,DeEulis T,Rowley K,Aron B

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:The aim of this report is to describe the potential clinical utility of tracer [F-18]-Fluorodeoxyglucose (FDG) uptake, quantitated as a standardized uptake value (SUV) by positron emission tomography (PET), to evaluate treatment response to neoadjuvant chemotherapy (NAC) in advanced uterine cervical cancer. ...

journal_title：Gynecologic oncology

authors： Yoshida Y,Kurokawa T,Kawahara K,Yagihara A,Tsuchida T,Okazawa H,Fujibayashi Y,Yonekura Y,Kotsuji F

更新日期：2004-12-01 00:00:00

abstract：:Melanoma represents the second most frequent vulvar malignancy, and yet is still considered to be an uncommon neoplasm. Several varieties of melanoma exist. A patient who was diagnosed with a rare subtype of melanoma as a primary vulvar process is presented here. To date, there is only one other reported case of neuro...

journal_title：Gynecologic oncology

authors： Byrne PR,Maiman M,Mikhail A,Harris M,Rosen Y

更新日期：1995-02-01 00:00:00

abstract：:The extent to which the antigenic phenotype of human epithelial ovarian cancer changes during the course of the disease is an issue that must be addressed in order to maximize the potential of antibody-directed imaging and therapy. We have obtained tumor specimens at two separate operations from ten patients with epit...

journal_title：Gynecologic oncology

authors： Rubin SC,Finstad CL,Hoskins WJ,Federici MG,Lloyd KO,Lewis JL Jr

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the efficacy of hysteroscopy, using normal saline (NS) or carbon dioxide (CO2) as the distention medium, in assessing tumor invasion of the uterine cervix by endometrial carcinoma. METHODS:A retrospective study was conducted in 200 consecutive patients with endometrial c...

journal_title：Gynecologic oncology

authors： Lo KW,Cheung TH,Yim SF,Chung TK

更新日期：2001-08-01 00:00:00

abstract：:Women with histopathologically confirmed cervical intraepithelial neoplasia (CIN) were followed at 3-month intervals in a randomized double-blinded trial to evaluate the efficacy of beta-carotene to cause regression of CIN. Questionnaire data, plasma levels of micronutrients, and a cervicovaginal lavage for human papi...

journal_title：Gynecologic oncology

authors： Romney SL,Ho GY,Palan PR,Basu J,Kadish AS,Klein S,Mikhail M,Hagan RJ,Chang CJ,Burk RD

更新日期：1997-06-01 00:00:00

abstract：:This study is based on a retrospective review of 156 patients with endometrial carcinoma from 1978 through 1984 who underwent primary surgical evaluation. All cases were retrospectively restaged using the newly adopted FIGO surgical staging. The preoperative FIGO clinical stage distribution for this study was as follo...

journal_title：Gynecologic oncology

authors： Wolfson AH,Sightler SE,Markoe AM,Schwade JG,Averette HE,Ganjei P,Hilsenbeck SG

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:To estimate the frequency of cervical cytologic/histologic discrepancies in a group of obstetric patients diagnosed as HIV infected by routine prenatal screening. Also, to determine if serum CD4 levels or sexually transmitted diseases (STDs) are associated with the occurrence of preinvasive cervical disease i...

journal_title：Gynecologic oncology

authors： Robinson WR,Barnes SE,Adams S,Perrin MS

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:While there is ample literature on prognostic factors for uterine cancer, currently there are nomeans to estimate an individual's risk for recurrence or to differentiate the risk of loco-regional recurrence from distant recurrence. We addressed this gap by developing nomograms to individualize the risk of rec...

journal_title：Gynecologic oncology

authors： Kondalsamy-Chennakesavan S,Yu C,Kattan MW,Leung Y,Sykes P,Nascimento M,Nicklin J,Perrin L,Crandon A,Chetty N,Land R,Garrett A,Obermair A

更新日期：2012-06-01 00:00:00

abstract：STUDY OBJECTIVE:To describe our technique for excision of the pre-caval and laterocaval nodes using an extraperitoneal approach. This technique was developed to make the dissection and excision of the less accessible nodes in an easier and safer way by minimizing the risk of great vessels injury and bleeding. DESIGN:S...

journal_title：Gynecologic oncology

authors： Gorostidi M,Villalain C,Ruiz R,Jaunarena I,Lekuona A

更新日期：2018-01-01 00:00:00

abstract：:Over a 7-year period from 1987 to 1994, 120 patients consecutive patients with FIGO stage IB invasive cervical cancer who underwent type 3 radical abdominal hysterectomy and bilateral pelvic lymphadenectomy had either Jackson-Pratt closed-suction drainage (Group 1, patients 1-60) or no drainage (Group 2, patients 61-1...

journal_title：Gynecologic oncology

authors： Patsner B

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:Inappropriate telomerase expression has been reported to be associated with the development and/or progression of malignancies. Therefore, the purpose of the study was to determine and evaluate the levels of telomerase activity in normal ovary, cystadenomas, low-malignant-potential tumors, and carcinomas of t...

journal_title：Gynecologic oncology

authors： Datar RH,Naritoku WY,Li P,Tsao-Wei D,Groshen S,Taylor CR,Imam SA

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:Persistent infection with oncogenic human papillomavirus (HPV) is known to be the necessary cause of cervical cancer and a majority of vulvar cancers. Persistent HPV infections must evade host immune responses, including cytokines released by activated T-helper (Th) cells. In this study, we investigated the r...

journal_title：Gynecologic oncology

authors： Hardikar S,Johnson LG,Malkki M,Petersdorf EW,Galloway DA,Schwartz SM,Madeleine MM

更新日期：2015-10-01 00:00:00