Rat ear transplantation: a feasibility study.

Abstract:

:The feasibility of rat ear replantation and its inherent advantages as an experimental model have previously been demonstrated. The purpose of this study was to validate the technical feasibility of rat ear transplantation. To eliminate immunologic rejection as a complicating factor, highly inbred Lewis rats (strain LEW/CRIBR) were utilized. The external, internal, or common carotid artery served as the arterial pedicle, and the posterior facial vein as the venous pedicle; tubal cartilage was anastomosed for structural support. Four of five transplanted ears were viable at 10 to 14 weeks postoperatively. The other ear appeared entirely viable, when its host animal died of respiratory complications on postoperative day 2. Rat ears therefore seem to provide a feasible model for transplantation of non-vital organs.

journal_name

J Reconstr Microsurg

authors

Chiu DT,Ascherman JA,Patsis MC

doi

10.1055/s-2007-1006636

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

33-8

issue

1

eissn

0743-684X

issn

1098-8947

journal_volume

9

pub_type

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