Scanning electron microscopic observations on the endothelial healing mechanism of vessels.


:Systematic scanning electron microscopic observations of the healing mechanism in the endothelium of rat carotid arteries were carried out at the site of anastomosis. The site of needle holes and stitches are the main locations for thrombocyte adhesion and aggregation in normal vascular anastomosis. The repair process in endothelial injury can be divided into three stages. A thrombocyte-adhesion and filling stage is apparent at 1 hr postoperatively; this is also the period when thrombus is most likely to occur. A fibrin-covering stage is apparent at 2 hr after operation and reaches its peak in 24 hr. The formation of fibrin provides a framework for endothelial growth. In this period, there is still the possibility of thrombus formation. At 48 hr postoperatively, endothelial growth can be seen at the site of some needle holes. At 72 hr after operation, 47 percent of needle holes have endothelial growth, and the possibility of thrombus formation at the anastomotic site declines. The data suggest that eversion of the intima in vascular anastomosis and minimization of endothelial injury by considering the size of the needle hole, the duration of ischemia time, and perfection of surgical technique, are keys to the prevention of thrombus formation at the anastomotic site.


J Reconstr Microsurg


Gu YD,Li JF,Jiang JF,Zhong CS,Tang PZ


Has Abstract


1989-10-01 00:00:00












  • Successful reinnervation of the penis using an autogenous vein conduit.

    abstract::Injury to the dorsal sensory nerve of the penis following penile prosthesis insertion is extremely rare. The authors report on a patient with insensitivity involving the right penile shaft and glans secondary to entrapment and fibrosis of the dorsal cutaneous nerve of the penis, following penile prosthesis insertion. ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Nahabedian MY,Smolev JK

    更新日期:1998-01-01 00:00:00

  • The Role of Duplex Ultrasound in Microsurgical Reconstruction: Review and Technical Considerations.

    abstract:BACKGROUND: With the technological advances, microsurgery has evolved to the era of supermicrosurgery since its inception. With the popularization of these flaps, proficiency in using tools such as color Doppler ultrasound (CDU) has become crucial. Despite the increased interest, studies regarding the role of ultrasoun...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Cho MJ,Kwon JG,Pak CJ,Suh HP,Hong JP

    更新日期:2020-09-01 00:00:00

  • The profunda femoris artery "fourth perforator" island flap: a new perforator flap in lower-limb reconstruction.

    abstract::Although the lateral thigh flap has been well described as a fasciocutaneous flap based on one or more of the four perforators of the profunda femoris artery, the role for these individual perforators as perforator flaps has not been described. These profunda femoris artery perforators offer a particularly useful opti...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Rozen WM,Donahoe S,Wilson JL

    更新日期:2011-05-01 00:00:00

  • Superficial ulnar artery: embryology, case report, and clinical significance in reconstructive microsurgery.

    abstract::In this paper the authors describe and illustrate a rare anatomic variation of the ulnar artery, a superficial ulnar artery. The possible embryologic events responsible for this variation are discussed. In addition, they describe the surgical considerations that should be kept in mind when this abnormality is encounte...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Yuksel M,Yuksel E,Weinfeld AB,Shenaq SM

    更新日期:1999-08-01 00:00:00

  • Two-stage arterialized flow-through venous flap transfer for third-degree burn defects on the dorsum of the hand.

    abstract::A modified, two-stage arteriovenous flow-through venous flap was designed to repair skin defects due to third-degree burns on the dorsum of the hand in four patients. Two weeks after plasty of an arteriovenous (A-V) shunt between the greater saphenous vein and dorsalis pedis artery, the arterialized flow-through venou...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Ueda Y,Mizumoto S,Hirai T,Doi Y,Fukui A,Tamai S

    更新日期:1997-10-01 00:00:00

  • Standardized templates for shaping the fibula free flap in mandible reconstruction.

    abstract::Conversion of the straight fibula bone flap into the parabolic mandible shape can be performed using customized acrylic templates made from a 1:1 mandible computed tomography scan and lateral cephalogram. The premise of the current study is to objectively quantify the variability in a series of acrylic templates used ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Matros E,Santamaria E,Cordeiro PG

    更新日期:2013-11-01 00:00:00

  • Reverse end-to-side neurotization in a regenerating nerve.

    abstract::Bypass grafting around a neuroma-in-continuity entails coapting a nerve graft above and below the injured segment using two sequential end-to-side repairs. The proximal repair is analogous to what has been classically described as an end-to-side repair; the axons from the intact nerve sprout into the end of a recipien...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Isaacs JE,Cheatham S,Gagnon EB,Razavi A,McDowell CL

    更新日期:2008-10-01 00:00:00

  • Reverse Dorsoradial Flaps for Thumb Coverage Show Increased Sensory Recovery with Smaller Flap Sizes.

    abstract:BACKGROUND:Reverse homodigital dorsoradial (RHD) flap has been developed to repair soft-tissue defects of the thumb. However, few articles have reported this flap with long-term follow-up. This retrospective study was designed to evaluate the RHD flap and investigate factors affecting sensory recovery. METHODS:From Fe...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Sun YC,Chen QZ,Chen J,Gong YP,Gu JH

    更新日期:2015-07-01 00:00:00

  • Levator scapulae transfer and fascia lata fasciodesis for chronic spinal accessory nerve palsy.

    abstract::A retrospective evaluation of the functional results after reconstructive treatment with levator scapulae transfer and scapulo-spinal fasciodesis by fascia lata slings for complete chronic trapezius palsy is presented. Five patients (ages 6 to 40 years) were operated on between 1988 and 1991 because of incapacitating ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Coessens BC,Wood MB

    更新日期:1995-07-01 00:00:00

  • The emerging role of the direct cutaneous muscle perforator found arising from the muscle vessel hilum.

    abstract::Perforator flaps based on either musculocutaneous or septocutaneous perforators are no longer a curiosity, but rather in the past decade have become "workhorse" soft tissue alternatives. Yet a keener understanding of their anatomy abetted by sophisticated imaging techniques has revealed other deep fascia perforators w...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章,评审


    authors: Hallock GG

    更新日期:2012-10-01 00:00:00

  • Intraoperative Use of Vasopressors Is Safe in Head and Neck Free Tissue Transfer.

    abstract:BACKGROUND:The purpose of this study is to identify whether intraoperative use of vasoactive medications increases the risk of free flap failure or complications through a systematic review and meta-analysis. MATERIALS AND METHODS:PubMed/MEDLINE, EMBASE, and Scopus databases were searched for studies published through...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章,meta分析,评审


    authors: Swanson EW,Cheng HT,Susarla SM,Yalanis GC,Lough DM,Johnson O 3rd,Tufaro AP,Manson PN,Sacks JM

    更新日期:2016-02-01 00:00:00

  • Microsurgical repair of Stensen's duct using an interposition vein graft.

    abstract::Facial wounds are frequently associated with bone fractures and multiple trauma; however, disruption of the parotid gland or Stensen's duct is rare and is often associated with facial nerve palsy. Lesions are often undiagnosed on first assessment of the multiple trauma patient. If microsurgical repair of Stensen's duc...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Heymans O,Nélissen X,Médot M,Fissette J

    更新日期:1999-02-01 00:00:00

  • The Preferred Management of a Single-Digit Distal Phalanx Amputation.

    abstract:BACKGROUND: Replantation of a single digit at the distal phalanx level is not routinely performed since it is technically challenging with questionable cost-effectiveness. The purpose of this study was to analyze international microsurgeons' clinical decisions when faced with this common scenario. METHODS: A survey of...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Kwon SH,Lao WW,Hsu AT,Lee CH,Hsu CC,Huang JJ,Qiu SS,Tilkorn D,Tang ET,Lu JC,Chang TN

    更新日期:2020-05-01 00:00:00

  • Outcomes of Subfascial, Suprafascial, and Super-Thin Anterolateral Thigh Flaps: Tailoring Thickness without Added Morbidity.

    abstract:BACKGROUND: Subfascial anterolateral thigh (ALT) flap thickness can be problematic with regards to bulk, oral competence, shoe-fit, or as a potential source of recurrent wound breakdown. We have utilized distinct upper thigh fascial planes to fashion thin (suprafascial) or super-thin (periscarpal) ALT flaps to improve ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Diamond S,Seth AK,Chattha AS,Iorio ML

    更新日期:2018-03-01 00:00:00

  • Attributes and shortcomings of acoustic Doppler sonography in identifying perforators for flaps from the lower extremity.

    abstract::The preoperative identification of perforators can facilitate the appropriate design of perforator flaps from the lower extremity. Although computed tomographic arteriography can now be considered the gold standard in this regard, this technology is not universally available or inexpensive, with a nonnegligible risk f...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Hallock GG

    更新日期:2009-07-01 00:00:00

  • Postoperative Free Flap Breast Protocol Optimizing Resources and Patient Safety.

    abstract:BACKGROUND: As deep inferior epigastric artery perforator (DIEP) flaps have gained popularity in breast reconstruction, the postoperative care of these patients, including the appropriate hospital length-of-stay and the need for intensive care unit (ICU) admission, has become a topic of debate. At our institution, we h...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Fadavi D,Haley A,Khavanin N,Kraenzlin F,Bos TJ,Cho BH,Carl HM,Bhat D,Ostrander BT,Manahan MA,Rosson GD,Sacks JM

    更新日期:2020-06-01 00:00:00

  • Morphomic analysis for preoperative donor site risk assessment in patients undergoing abdominal perforator flap breast reconstruction: a proof of concept study.

    abstract:BACKGROUND:Morphomics are three-dimensional measurements of aspects of the human anatomy generated by computed tomographic (CT) imaging. The purpose of this study was to generate preliminary data on the efficacy of morphomics, as a potential risk stratification tool, in predicting abdominal donor site wound-healing com...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Levi B,Rinkinen J,Kidwell KM,Benedict M,Stein IC,Lisiecki J,Enchakalody B,Wang SC,Kozlow JH,Momoh AO

    更新日期:2014-11-01 00:00:00

  • Penile reconstruction with bilateral superficial circumflex iliac artery perforator (SCIP) flaps.

    abstract::The free radial forearm flap is a very common material for penile reconstruction. Its major problems are donor-site morbidity with large depressive scar after skin grafting, urethral fistula due to insufficiency of suture line for the urethra, and need for microvascular anastomosis. A new method using combined bilater...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Koshima I,Nanba Y,Nagai A,Nakatsuka M,Sato T,Kuroda S

    更新日期:2006-04-01 00:00:00

  • Reconstruction of a floating thumb with an excess big toe.

    abstract::In a three-year-11-month-old girl, an excess big toe was transferred microsurgically to replace a congenital floating thumb. The reconstructed thumb was evaluated nine years after the transfer. It showed almost normal growth, compared with the contralateral side, and the aesthetic result was excellent. However, the pa...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Harashina T,Inoue T,Fujino T,Uchinishi K,Itoh Y

    更新日期:1994-01-01 00:00:00

  • A preclinical canine model for composite tissue transplantation.

    abstract::The feasibility of composite tissue allografts (CTAs) has been demonstrated by the successful transplantation of the hand, abdomen, and face. However, the survival of these transplants depends on immunosuppression. Our laboratory is interested in achieving tolerance to decrease the risks associated with the use of chr...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Mathes DW,Noland M,Graves S,Schlenker R,Miwongtum T,Storb R

    更新日期:2010-04-01 00:00:00

  • A case of replantation of a completely amputated digit after 26 hours of warm ischemia.

    abstract::A seven-year-old-boy received a digit replantation after 26 hours of warm ischemia and showed good recovery of motor and sensory functions. In the case reported, replantation was performed after a much longer ischemic time than had been considered an indication for the procedure in previous reports. Successful replant...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Seo T,Matsuda M

    更新日期:1987-01-01 00:00:00

  • Microvascular reconstruction of a devascularized ileal segment during ileo-anal anastomosis.

    abstract::Endorectal ileo-anal anastomosis has become a mainstay of continent bowel reconstruction after total colectomy. However, the procedure is often aborted because of lack of vessel length for the formation of the ileal pouch. The use of microsurgical techniques to lengthen mesenteric vessels and to allow completion of th...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Chick LR,Brown RE,Walton RL

    更新日期:1988-10-01 00:00:00

  • The treatment of peripheral nerve injuries using irradiated allografts and temporary host immunosuppression (in a rat model).

    abstract::Irradiation of allografts prior to transplantation and host immunosuppression with cyclosporin-A were studied separately and in combination as means of lessening the rejection of transplanted peripheral nerve tissue. Lewis and Brown Norway rats were used in the animal model, as they differ at both major and minor hist...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Easterling KJ,Trumble TE

    更新日期:1990-10-01 00:00:00

  • Effects of late loss of arterial inflow on free flap survival.

    abstract::Greater than 80 percent of free flap thromboses have been shown to occur within the first three postoperative days, warranting immediate re-exploration and restoration of adequate vessel patency. The infrequency of thromboses beyond this period is reflected in the lack of reported cases in the literature and the absen...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Salgado CJ,Smith A,Kim S,Higgins J,Behnam A,Herrera HR,Serletti JM

    更新日期:2002-10-01 00:00:00

  • Quantification of neutrophil adhesion to skeletal muscle venules following ischemia-reperfusion.

    abstract::Ischemia-reperfusion is encountered in a wide variety of surgical situations. The damage resulting from ischemia-reperfusion may be due, in part, to the infiltration and activation of neutrophils into the reperfused tissue. The purpose of the study was to examine ischemia-reperfusion induced neutrophil activation in s...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Goldberg M,Serafin D,Klitzman B

    更新日期:1990-07-01 00:00:00

  • Effects of Systemic and Local Caffeine on Vessel Diameter, Anastomosis Patency, and Intimal Hyperplasia in the Rat.

    abstract:BACKGROUND: The use of caffeine is not recommended prior to elective microsurgery due to its demonstrated negative effects on vessel anastomosis by the presumed sympathomimetic induction of vasoconstriction. In this study, we aimed to elucidate the systemic and local effects of caffeine on vessel diameter, anastomosis ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Sakarya AH,Uzun H,Türkkanı A,Çakar AN,Hsieh YH,Üstün GG,Şafak T

    更新日期:2019-05-01 00:00:00

  • Indocyanine Green Lymphography, Lymphoscintigraphy, and Genetic Analysis in Nonsyndromic Primary Lymphedema: The Distal Dermal Backflow Grading System and the Print Sign.

    abstract:BACKGROUND: Investigating correlations between clinical, instrumental, and genetic features of primary lymphedema (PL) with the aim to facilitate the diagnosis, the staging, and the management of this subgroup of patients. METHODS: A prospective observational study was conducted from September 2016 to May 2018, includ...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Mangialardi ML,Lorenzano V,Pagliara D,Visconti G,Gentileschi S,Salgarello M

    更新日期:2020-03-01 00:00:00

  • Rat-strain differences in recovery following peripheral-nerve allotransplantation.

    abstract::The rat model is commonly utilized in peripheral nerve research. Due to the short length of the rat limb and the animal's inherent neuroregenerative capacity, the timing of assessment of nerve regeneration is critical, and significant differences between groups can be lost if assessment is done too late. Additionally,...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Calvert GT,Doolabh VB,Grand AG,Hunter DA,Mackinnon SE

    更新日期:2001-04-01 00:00:00

  • The effect of ammonium sulfate injection on peripheral nerve.

    abstract::Local anesthetic drugs with prolonged nerve-block effect would have clinical application for postoperative or neuromatous pain relief. This study evaluated the possibility of peripheral nerve neurotoxicity by injection of 10 percent ammonium sulfate. Both intrafascicular and extrafascicular injection of 10 percent amm...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Kobayashi J,Mackinnon SE,Langer JC,Hertl MC,Hunter DA,Tarasidis G

    更新日期:1997-08-01 00:00:00

  • Microvascular anastomosis using cyanoacrylate adhesives.

    abstract::This paper describes a new technique for microvascular anastomosis, which involves the overlapping of the adventitias of the two ends of a severed blood vessel, and then painting a cyanoacrylate adhesive on the outer surface of the vessel around the anastomosed part. Sixteen anastomoses were performed in both radial a...

    journal_title:Journal of reconstructive microsurgery

    pub_type: 杂志文章


    authors: Kim BY,Choi BH,Huh JY,Lee SH,Zhu SJ,Cho BP

    更新日期:2004-05-01 00:00:00