Intramyocardial hypercarbic acidosis during cardiac arrest and resuscitation.

abstract：OBJECTIVES:Brain death induces a massive inflammatory response. However, the influence of this inflammatory response on organ procurement, transplantation, and recipient outcome is unknown. We describe the inflammatory response characteristics in brain-dead organ donors and examine associations with organ transplantati...

journal_title：Critical care medicine

authors： Murugan R,Venkataraman R,Wahed AS,Elder M,Hergenroeder G,Carter M,Madden NJ,Powner D,Kellum JA,HIDonOR Study Investigators.

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:Increasing age is a well-recognized risk factor for in-hospital mortality in patients receiving extracorporeal membrane oxygenation for cardiogenic shock, but the shape of this relationship is unknown. In addition, the impact of age on hospital length of stay, patterns of patient disposition, and costs has b...

journal_title：Critical care medicine

authors： Chung M,Zhao Y,Strom JB,Shen C,Yeh RW

更新日期：2019-03-01 00:00:00

abstract：:This report describes an unusual hemolytic transfusion reaction. A group O donor was inadvertently transfused with 100 ml of group A red cells during the course of plasmapheresis. Granulocytopenia, thrombocytopenia, hypofibrinogenemia and low levels of factors V, VIII, and IX developed immediately after the infusion. ...

journal_title：Critical care medicine

authors： McKenna PJ,Scheinman HZ

更新日期：1975-01-01 00:00:00

abstract：:The current definition of sepsis is life-threatening, acute organ dysfunction secondary to a dysregulated host response to infection. Criteria to operationalize this definition can be judged by six domains of usefulness (reliability, content, construct and criterion validity, measurement burden, and timeliness). The r...

journal_title：Critical care medicine

authors： Seymour CW,Coopersmith CM,Deutschman CS,Gesten F,Klompas M,Levy M,Martin GS,Osborn TM,Rhee C,Warren DK,Watson RS,Angus DC

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Hemoglobin (Hb) induces vasoconstriction by heme group binding nitric oxide in an irreversible fashion. Recent in vitro studies indicate that the thiol groups in Hb reversibly bind nitric oxide and participate in trans-nitrosylation reactions with other thiols. Sepsis is a pathophysiologic state characterize...

journal_title：Critical care medicine

authors： Tejedor C,Lorente JA,Delgado MA,Fernández-Segoviano P,De Paula M,Tobalina R,Alonso M,Moscoso A,Soto F,Blázquez J,Esteban A

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVES:To develop a valid, reliable measure that reflected the environment of respectfulness within the ICU setting. DESIGN:We developed a preliminary survey instrument based on conceptual domains of respect identified through prior qualitative analyses of ICU patient, family member, and clinician perspectives. Th...

journal_title：Critical care medicine

authors： Beach MC,Topazian R,Chan KS,Sugarman J,Geller G

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To determine whether four stages of weaning (acute, prewean, wean, and outcome) could be identified by using clinical instruments designed to quantify severity of illness, patient stability, or weaning readiness. The instruments used were the Acute Physiology and Chronic Health Evaluation (APACHE III), the Th...

journal_title：Critical care medicine

authors： Burns SM,Ryan B,Burns JE

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:Randomized trials have suggested that hypertonic saline solutions may be superior to mannitol for the treatment of elevated intracranial pressure, but their impact on clinical practice has been limited, partly by their small size. We therefore combined their findings in a meta-analysis. DATA SOURCES:We sear...

journal_title：Critical care medicine

authors： Kamel H,Navi BB,Nakagawa K,Hemphill JC 3rd,Ko NU

更新日期：2011-03-01 00:00:00

abstract：:Thromboembolic disease ranks among the most dangerous and common complication in the postoperative or post-traumatic patient. As previously mentioned, the incidence is increasing and fatalities from this complication have also risen substantially. The pathogenesis of thromboembolic disease and the predictability of it...

journal_title：Critical care medicine

authors： Evarts CM

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVES:Sepsis remains a serious clinical problem despite intensive research efforts and numerous attempts to improve outcome by modifying the inflammatory response. Substance P, the principal ligand for the neurokinin-1 receptor, is a potent proinflammatory mediator that exacerbates inflammatory responses and cardi...

journal_title：Critical care medicine

authors： Mella JR,Chiswick E,Stepien D,Moitra R,Duffy ER,Stucchi A,Remick D

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To study the impact of diabetes mellitus on the relationship between glycemia and mortality in critically ill patients. DESIGN:Retrospective observational study. SETTING:Intensive care units of two university hospitals. PATIENTS:Cohort of 4946 critically ill patients including 728 patients with diabetes me...

journal_title：Critical care medicine

authors： Egi M,Bellomo R,Stachowski E,French CJ,Hart GK,Hegarty C,Bailey M

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:To compare usual care with a proactive case-finding approach for critically ill patients with terminal dementia using an inpatient palliative care service. DESIGN:Prospective comparison to historical control. SETTING:Urban, university-affiliated hospital. PATIENTS:Total of 52 men and women with end-stage ...

journal_title：Critical care medicine

authors： Campbell ML,Guzman JA

更新日期：2004-09-01 00:00:00

abstract：:As of October 1985, 37 candidates have passed the final examination in intensive care for the Diploma of Fellow of the Faculty of Anaesthetists, Royal Australasian College of Surgeons (FFARACS). In September 1984, 23 of these successful candidates responded to a questionnaire seeking information on their educational e...

journal_title：Critical care medicine

authors： Byth PL,Harrison GA

更新日期：1986-06-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to test the ability of myoglobin removal of a novel, high-permeability polysulphone dialyzer in acute kidney injury as a result of rhabdomyolysis. SETTING:Intensive care unit of a tertiary care hospital. PATIENTS:Six patients (one female; aged 24, 36, 41, 55, 63, and 65 yrs) ...

journal_title：Critical care medicine

authors： Sorrentino SA,Kielstein JT,Lukasz A,Sorrentino JN,Gohrbandt B,Haller H,Schmidt BM

更新日期：2011-01-01 00:00:00

abstract：:The recommended rates for closed-chest cardiac compressions during CPR are based on physiologic variations with increasing age rather than experimental data. Using puppies, we compared mean arterial pressure, cardiac index (CI), and cerebral blood flow (CBF) at a slow (40/min, group 1) and a rapid (120/min, group 2) r...

journal_title：Critical care medicine

authors： Fleisher G,Delgado-Paredes C,Heyman S

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND AND METHODS:Calcium-channel blockers may attenuate vasospasm after transient ischemia and improve organ blood flow after resuscitation. Our aim was to assess the effect of diltiazem on systemic oxygen delivery and consumption, hemodynamics, electroencephalogram (EEG), and organ blood flow after restoration o...

journal_title：Critical care medicine

authors： Lindner KH,Prengel AW,Ahnefeld FW,Ensinger H,Schürmann W

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:To date, no study has systematically investigated the impact of drowning-induced asphyxia on hemostasis. Our objective was to test the hypothesis that asphyxia induces bleeding by hyperfibrinolytic disseminated intravascular coagulation. DESIGN:Observational study. SETTING:A 2,100-bed tertiary care facility...

journal_title：Critical care medicine

authors： Schwameis M,Schober A,Schörgenhofer C,Sperr WR,Schöchl H,Janata-Schwatczek K,Kürkciyan EI,Sterz F,Jilma B

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Mannitol is widely used in hospitals worldwide to treat patients with high intracranial pressure and/or cerebral edema. One of the mechanisms by which mannitol is thought to affect intracranial pressure is by increasing the patient's serum osmolarity, but not the osmolarity in the brain or cerebrospinal fluid...

journal_title：Critical care medicine

authors： Polderman KH,van de Kraats G,Dixon JM,Vandertop WP,Girbes AR

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To provide a meta-analysis of current literature concerning the validation of thoracic impedance cardiography (TIC) and to explain the variations in the reported results from the differences in the studies. DATA SOURCES:A computer-assisted search of English-language, German, and Dutch literature was performe...

journal_title：Critical care medicine

authors： Raaijmakers E,Faes TJ,Scholten RJ,Goovaerts HG,Heethaar RM

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:To assess the amount of nutrients delivered, prescribed, and required for critically ill patients and to identify the reasons for discrepancies between prescriptions and requirements and between prescriptions and actual delivery of nutrition. DESIGN:Prospective cohort study. SETTING:Twelve-bed medical inte...

journal_title：Critical care medicine

authors： De Jonghe B,Appere-De-Vechi C,Fournier M,Tran B,Merrer J,Melchior JC,Outin H

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Procalcitonin has been advocated as a specific biomarker for bacterial infection. We performed this study to determine whether accuracy of procalcitonin for diagnosis of postoperative bacterial infection is affected by renal function after aortic surgery. DESIGN:Single-center prospective study. SETTING:Univ...

journal_title：Critical care medicine

authors： Amour J,Birenbaum A,Langeron O,Le Manach Y,Bertrand M,Coriat P,Riou B,Bernard M,Hausfater P

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Increased cardiac index, oxygen delivery (DO2), and oxygen consumption (VO2) patterns were shown to characterize the physiologic status of surviving high-risk surgical patients, and indicate increased metabolic needs; relatively normal DO2 and VO2 values were found to characterize the sequential pattern of n...

journal_title：Critical care medicine

authors： Shoemaker WC,Appel PL,Kram HB

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and tolerability of intravenous empiric treatment with meropenem compared with ceftazidime-tobramycin in patients with hospital-acquired lower respiratory tract infections. DESIGN:Prospective, nonblind, randomized trial. SETTING:Multicenter trial conducted at 22 centers. PATIENTS:T...

journal_title：Critical care medicine

authors： Sieger B,Berman SJ,Geckler RW,Farkas SA

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVES:Centers for Disease Control and Prevention built up new surveillance paradigms for the patients on mechanical ventilation and the ventilator-associated events, comprising ventilator-associated conditions and infection-related ventilator-associated complications. We assess 1) the current epidemiology of venti...

journal_title：Critical care medicine

authors： Bouadma L,Sonneville R,Garrouste-Orgeas M,Darmon M,Souweine B,Voiriot G,Kallel H,Schwebel C,Goldgran-Toledano D,Dumenil AS,Argaud L,Ruckly S,Jamali S,Planquette B,Adrie C,Lucet JC,Azoulay E,Timsit JF,OUTCOMEREA Study

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:To determine whether aerosolized antibiotics can be delivered efficiently to the lower respiratory tract in mechanically ventilated patients and to define possible clinical responses to these agents. DESIGN:Prospective serial study with cases as their own control. SETTING:A 10-bed respiratory care unit for...

journal_title：Critical care medicine

authors： Palmer LB,Smaldone GC,Simon SR,O'Riordan TG,Cuccia A

更新日期：1998-01-01 00:00:00

abstract：:The image of the physician as a therapist, as well as the general perception of the physician's role in society and in the life of patients and their families, has changed dramatically in past decades. In response, many conferences, editorials, and planning activities for medical and premedical curricula have been dev...

journal_title：Critical care medicine

authors： Detre K

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVES:To perform a complete immunological characterization of compensatory anti-inflammatory response syndrome in patients with sepsis and to explore the relationship between these changes and clinical outcomes of 28-day mortality and secondary infections. DESIGN:Prospective single-center study conducted between ...

journal_title：Critical care medicine

authors： Gomez HG,Gonzalez SM,Londoño JM,Hoyos NA,Niño CD,Leon AL,Velilla PA,Rugeles MT,Jaimes FA

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:The role of family interests in medical decision making is controversial. Physicians who routinely treat incompetent patients may have preferred strategies for addressing family interests as they are encountered in surrogate medical decision making. We sought to determine how physicians view the role of famil...

journal_title：Critical care medicine

authors： Hardart GE,Truog RD

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:This survey was designed to study current practices in the monitoring and treatment of patients with severe head injury in the United States. DATA SOURCES:The collected data represent answers to telephone interviews of nurse managers, clinical specialists, and staff nurses specializing in neurotrauma care at...

journal_title：Critical care medicine

authors： Ghajar J,Hariri RJ,Narayan RK,Iacono LA,Firlik K,Patterson RH

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVE:Artery puncture and hematoma formation are the most common immediate complications during internal jugular vein catheterization. This study was performed to assess whether the bevel-down approach of the puncture needle decreases the incidence of posterior venous wall damage and hematoma formation during inter...

journal_title：Critical care medicine

authors： Lim T,Ryu HG,Jung CW,Jeon Y,Bahk JH

更新日期：2012-02-01 00:00:00