Abstract：
:Currently, diagnosis and management of disorders involving nerves are generally undertaken without images of the nerves themselves. The authors evaluated whether direct nerve images obtained using the new technique of magnetic resonance (MR) neurography could be used to make clinically important diagnostic distinctions that cannot be readily accomplished using existing methods. The authors obtained T2-weighted fast spin-echo fat-suppressed (chemical shift selection or inversion recovery) and T1-weighted images with planes parallel or transverse to the long axis of nerves using standard or phased-array coils in healthy volunteers and referred patients in 242 sessions. Longitudinal and cross-sectional fascicular images readily distinguished perineural from intraneural masses, thus predicting both resectability and requirement for intraoperative electrophysiological monitoring. Fascicle pattern and longitudinal anatomy firmly identified nerves and thus improved the safety of image-guided procedures. In severe trauma, MR neurography identified nerve discontinuity at the fascicular level preoperatively, thus verifying the need for surgical repair. Direct images readily demonstrated increased diameter in injured nerves and showed the linear extent and time course of image hyperintensity associated with nerve injury. These findings confirm and precisely localize focal nerve compressions, thus avoiding some exploratory surgery and allowing for smaller targeted exposures when surgery is indicated. Direct nerve imaging can demonstrate nerve continuity, distinguish intraneural from perineural masses, and localize nerve compressions prior to surgical exploration. Magnetic resonance neurography can add clinically useful diagnostic information in many situations in which physical examinations, electrodiagnostic tests, and existing image techniques are inconclusive.
journal_name
J Neurosurgjournal_title
Journal of neurosurgeryauthors
Filler AG,Kliot M,Howe FA,Hayes CE,Saunders DE,Goodkin R,Bell BA,Winn HR,Griffiths JR,Tsuruda JSdoi
10.3171/jns.1996.85.2.0299subject
Has Abstractpub_date
1996-08-01 00:00:00pages
299-309issue
2eissn
0022-3085issn
1933-0693journal_volume
85pub_type
杂志文章abstract：OBJECT:The authors tested the hypothesis in a porcine model that inhibition of nitric oxide synthesis during reduced cerebral perfusion pressure (CPP) affected the relative cerebral blood flow (CBF) and the cerebrovascular resistance. METHODS:The CPP was reduced by inducing high cerebrospinal fluid pressure and hemorr...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1998.89.3.0448
更新日期：1998-09-01 00:00:00
abstract：OBJECT:Age-related macular degeneration (AMD) is the leading cause of severe vision loss in people older than age 65 years in the western world. The visual acuity loss usually results from the ingrowth of new vessels from the choroid capillaries, so called choroidal neovascularization (CNV). The aim of this pilot study...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2000.93.supplement
更新日期：2000-12-01 00:00:00
abstract：:The authors report unanticipated intraoperative intracranial hemorrhaging in two pediatric neurosurgical patients. Both children were undergoing elective craniotomies with the aid of intraoperative magnetic resonance (iMR) imaging. In both cases, the ability of iMR imaging to aid in diagnosis allowed prompt and defini...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/ped.2007.106.5.398
更新日期：2007-05-01 00:00:00
abstract：:One hundred and thirty-three patients with chronic subdural hematoma were treated surgically between 1943 and 1980. The patients, aged 5 to 84 years, were graded retrospectively according to the Bender scale; 28% were in Grades 3 and 4. There were 107 unilateral and 26 bilateral hematomas. The clots were removed mostl...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1984.61.2.0263
更新日期：1984-08-01 00:00:00
abstract：:Myelomeningoceles are routinely diagnosed prenatally by using ultrasonography. Because the level of the neural defect has been shown to correlate with functional and cognitive outcome in infants with myelomeningocele, it is of prognostic importance to identify the level prenatally. The authors report on a case in whic...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/jns.2005.102.2.0248
更新日期：2005-03-01 00:00:00
abstract：:The authors present the rare case of a myxoma, a benign soft-tissue tumor of mesenchymal origin noted for occurring in the left atrium of the heart, which was found in the lumbar paraspinal muscles of an 80-year-old woman. This patient experienced low-back pain for over 20 years and had noted its increasing severity w...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/spi.2001.95.2.0260
更新日期：2001-10-01 00:00:00
abstract：OBJECTIVE:The optimal margin size in postoperative stereotactic radiosurgery (SRS) for brain metastases is unknown. Herein, the authors investigated the effect of SRS planning target volume (PTV) margin on local recurrence and symptomatic radiation necrosis postoperatively. METHODS:Records of patients who received pos...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2017.9.JNS171735
更新日期：2018-04-20 00:00:00
abstract：:In patients with pineal tumors, clinical symptoms are due to direct compression of adjacent structures. The most common signs include increased intracranial pressure (80%) caused by obstruction of the sylvian aqueduct, and Parinaud syndrome (50%) caused by direct compression of the superior colliculi. Hearing loss is ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2003.99.3.0587
更新日期：2003-09-01 00:00:00
abstract：:The authors report outcomes in 18 patients with arteriovenous malformations (AVMs) who were treated with gamma knife radiosurgery and in whom magnetic resonance (MR) imaging was obtained a mean of 14 years (range 8-23 years) after treatment and 10 years (range 4-17 years) after confirmed obliteration of the AVM. All p...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1997.86.4.0589
更新日期：1997-04-01 00:00:00
abstract：OBJECTIVE:In daily practice, neurosurgeons face increasing numbers of patients using aspirin (acetylsalicylic acid, ASA). While many of these patients discontinue ASA 7-10 days prior to elective intracranial surgery, there are limited data to support whether or not perioperative ASA use heightens the risk of hemorrhagi...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2018.12.JNS182483
更新日期：2019-04-05 00:00:00
abstract：:Are spinal schwannomas as benign as we think? To what extent do patients recover? Are patients prone to develop late complications such as cystic myelopathy or symptomatic spinal deformity? Is their life expectancy compromised? In an effort to answer these questions, the authors analyzed the long-term outcome for 187 ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1995.83.4.0621
更新日期：1995-10-01 00:00:00
abstract：:Results of computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), xenon-133 measurement of cerebral blood flow (CBF), and neuropsychological assessments are described in three head-injured patients. The patients were selected because they presented with intracranial hemorrh...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1986.64.5.0760
更新日期：1986-05-01 00:00:00
abstract：OBJECT:Historically, destructive procedures for cancer pain were the main line of treatment therapy. However, the use of high-dose opioids has essentially replaced such procedures. Recognition of the limits of medical therapy to treat cancer pain effectively is growing, while conversely, in regions with limited access ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/2010.6.JNS10119
更新日期：2011-01-01 00:00:00
abstract：:This report describes 60 dural specimens from patients with pituitary adenomas treated by transsphenoidal microsurgery, and attempts to define more precisely the clinical and pathological correlation of microscopic dural invasion. Analysis of the adenomas was based on four characteristics; size, surgical invasiveness ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1986.64.3.0402
更新日期：1986-03-01 00:00:00
abstract：:Tumors of the cranial nerves are uncommon, and are usually schwannomas or neurofibromas. The authors describe a case of a fibroblastic tumor involving the sixth cranial nerve. Based upon electron microscopy and immunohistochemistry, the tumor was not of nerve-sheath origin, but was comprised of fibroblasts. Clinical, ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1985.62.2.0296
更新日期：1985-02-01 00:00:00
abstract：OBJECT:Glutamate is important in the pathogenesis of brain damage after cerebral ischemia and traumatic brain injury. Notably, brain extracellular and cerebrospinal fluid as well as blood glutamate concentrations increase after experimental and clinical trauma. While neurons are one potential source of glutamate, plate...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2014.3.JNS132130
更新日期：2014-12-01 00:00:00
abstract：:The authors describe a novel approach to the management of high-output heart failure secondary to an intracranial high-flow dural arteriovenous fistula (DAVF) by using extracorporeal membrane oxygenation (ECMO). To the best of the authors' knowledge, this represents the first report of an embolization performed in con...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/ped.2004.100.2.0197
更新日期：2004-02-01 00:00:00
abstract：:All patients who underwent decompressive lumbar laminectomy in the Washtenaw County, Michigan metropolitan area during a 7-year period were studied for the purpose of defining long-term outcome, clinical correlations, and the need for subsequent fusion. Outcome was determined by questionnaire and physical examination ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1994.81.5.0699
更新日期：1994-11-01 00:00:00
abstract：:Between 1925 and 1945, Walter Dandy and Kenneth McKenzie performed more than 700 posterior fossa eighth nerve sections and vestibular neurectomies to treat the intractable vertigo accompanying Ménière's disease. During the past 10 years, with the aid of microsurgical techniques and the approach to the posterior fossa ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1990.72.4.0533
更新日期：1990-04-01 00:00:00
abstract：:This is a report of five cases in which a bullet penetrated the vertex of the skull and brain, apparently during its vertical descent after having been fired into the air. ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1971.34.2part1.0222
更新日期：1971-02-01 00:00:00
abstract：:To test the hypothesis that concussive brain injury interferes with the normal vasodilator response of the cerebral circulation to hypoxemia, 30 cats were subjected to mild (PaO2 50 mm Hg) and severe (PaO2 30 mm Hg) hypoxemia while measurements were made of arterial and intracranial pressure, regional cerebral blood f...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1982.56.3.0332
更新日期：1982-03-01 00:00:00
abstract：:The lower brainstem and cervical spinal cord from an ordinarily treated case of Chiari Type I hindbrain hernia associated with syringomyelia was examined using high-resolution magnetic resonance microscopy and standard neuropathological techniques. Magnetic resonance microscopy allows total screening and visualizes th...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1996.85.4.0701
更新日期：1996-10-01 00:00:00
abstract：OBJECT:Subarachnoid hemorrhage (SAH) from ruptured posterior inferior cerebellar artery (PICA) aneurysms is uncommon, and long-term outcome data for patients who have suffered such hemorrhages is lacking. This study investigated in-hospital and long-term clinical data from a prospective cohort of patients with SAH from...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2014.10.JNS141079
更新日期：2015-08-01 00:00:00
abstract：:The authors present the case of a 68-year-old man who experienced acute obstructive hydrocephalus after having suffered an infarction in the occipital lobe. Histopathological and serial neuroimaging examinations revealed that portions of a large disintegrating occipital infarct had entered the lateral ventricle and ob...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2001.95.1.0119
更新日期：2001-07-01 00:00:00
abstract：:A patient with a giant traumatic aneurysm of the right internal carotid artery presented with recurrent massive epistaxis 30 years after a head injury. During an episode of acute hemorrhage, this patient was effectively treated with occlusion of the internal carotid artery circulation by a detachable inflatable balloo...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1988.68.1.0142
更新日期：1988-01-01 00:00:00
abstract：OBJECT:Females comprise an increasing percentage of the athlete population across all age groups, and analysis of recent literature reveals that they sustain more concussions in collegiate sports. Results of human and animal studies indicate that females may have poorer outcomes after traumatic brain injury; however, n...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2005.102.5.0856
更新日期：2005-05-01 00:00:00
abstract：OBJECT:Chiari Type I malformation (CMI) is a congenital disorder recognized by caudal displacement of the cerebellar tonsils through the foramen magnum and into the cervical canal. Frequently, associated findings include abnormalities of nearby bony and neural elements as well as syringomyelia. Cerebellar tonsillar ect...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2000.92.6.0920
更新日期：2000-06-01 00:00:00
abstract：OBJECT:The aim of this study was to determine age-related differences in short-term (1-year) outcomes in patients with unruptured intracranial aneurysms (UIAs). METHODS:Four thousand fifty-nine patients prospectively enrolled in the International Study of Unruptured Intracranial Aneurysms were categorized into 3 group...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.3171/2014.6.JNS121179
更新日期：2014-11-01 00:00:00
abstract：OBJECT:Sphenopalatine ganglion stimulation activates perivascular vasodilatory nerves in the ipsilateral anterior circle of Willis. This experiment tested whether stimulation of the ganglion could reverse vasospasm and improve cerebral perfusion after subarachnoid hemorrhage (SAH) in monkeys. METHODS:Thirteen cynomolg...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2010.6.JNS091525
更新日期：2011-04-01 00:00:00
abstract：:Suprascapular nerve entrapment (SNE) in the suprascapular notch is a rare entity that must be considered in the differential diagnosis of radicular pain, as well as that of shoulder discomfort. Over a period of 10 years (1985-1995), the authors treated 28 cases of SNE in 27 patients by surgical decompression of the ne...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1996.85.6.1020
更新日期：1996-12-01 00:00:00
