Therapeutic effect of β-blockers in triple-negative breast cancer postmenopausal women.

abstract：:To assess the impact of patient-provider communication on adherence to tamoxifen (TAM) and aromatase inhibitors (AIs) 36 months after breast cancer (BC) diagnosis in a low-income population of women. California statewide surveys were conducted among 921 low-income women with BC at 6, 18, and 36 months after BC diagnos...

journal_title：Breast cancer research and treatment

authors： Liu Y,Malin JL,Diamant AL,Thind A,Maly RC

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Differences in de novo (dnMBC) and recurrent metastatic breast cancer (rMBC) presentation and survival over time have not been adequately described. METHODS:A retrospective cohort study, 1990-2010, with follow up through 2015 of dnMBC patients (stage IV at diagnosis) and rMBC patients with subsequent distan...

journal_title：Breast cancer research and treatment

authors： Malmgren JA,Mayer M,Atwood MK,Kaplan HG

更新日期：2018-01-01 00:00:00

abstract：:The Breast Cancer Family Registry is a resource for interdisciplinary and translational studies of the genetic epidemiology of breast cancer. This resource is available to researchers worldwide for collaborative studies. Herein, we report the results of testing for germline mutations in BRCA1 and BRCA2. We have tested...

journal_title：Breast cancer research and treatment

authors： Neuhausen SL,Ozcelik H,Southey MC,John EM,Godwin AK,Chung W,Iriondo-Perez J,Miron A,Santella RM,Whittemore A,Andrulis IL,Buys SS,Daly MB,Hopper JL,Seminara D,Senie RT,Terry MB,Breast Cancer Family Registry.

更新日期：2009-07-01 00:00:00

abstract：:Genome-Wide Association Studies have identified several loci associated with breast cancer (BC) in populations of different ethnic origins. One of the strongest associations was found in the FGFR2 gene, and MAP3K1 has been proposed as a low-penetrance BC risk factor. In this study, we evaluated the associations among ...

journal_title：Breast cancer research and treatment

authors： Jara L,Gonzalez-Hormazabal P,Cerceño K,Di Capua GA,Reyes JM,Blanco R,Bravo T,Peralta O,Gomez F,Waugh E,Margarit S,Ibañez G,Romero C,Pakomio J,Roizen G

更新日期：2013-01-01 00:00:00

abstract：:A minority of early invasive breast cancers show a pattern of central necrosis and fibrosis (CNF). Previous studies have documented an adverse prognostic impact and association with other adverse pathological features, but its predictive importance for therapy selection is unknown. We examined the prognostic and predi...

journal_title：Breast cancer research and treatment

authors： Maiorano E,Regan MM,Viale G,Mastropasqua MG,Colleoni M,Castiglione-Gertsch M,Price KN,Gelber RD,Goldhirsch A,Coates AS

更新日期：2010-05-01 00:00:00

abstract：:We determined the expression of two transcriptional variants of thyroid hormone receptor alpha (THRα1 and THRα2) in samples from a cohort of breast cancer patients and correlated expression levels with survival. 130 women who were diagnosed with invasive breast carcinoma between 2007 and 2008 were included. Representa...

journal_title：Breast cancer research and treatment

authors： Jerzak KJ,Cockburn J,Pond GR,Pritchard KI,Narod SA,Dhesy-Thind SK,Bane A

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The significance of HER-2/neu results obtained by immunohistochemical analyses (IHC) which are neither negative nor strongly positive is controversial. The incidence of fluorescence in situ hybridization (FISH) positivity in these tumors is small and the implication is that these borderline results represent la...

journal_title：Breast cancer research and treatment

authors： Killeen JL,Ortega-Lopez A,Shaha J,Shaha SH,Fu JB

更新日期：2006-07-01 00:00:00

abstract：:In order to assess the impact of modern combination chemotherapy on overall survival of metastatic breast cancer patients, we retrospectively analysed survival data of those patients who presented with breast cancer and developed metastases at our clinic from 1971-78 inclusive. Our results indicate a trend towards imp...

journal_title：Breast cancer research and treatment

authors： Paterson AH,Szafran O,Cornish F,Lees AW,Hanson J

更新日期：1981-01-01 00:00:00

abstract：:The proportional hazards model is frequently used in analyzing the results of clinical trials, when it is often the case that the outcomes are right-censored. This model allows one to measure treatment effects and simultaneously identify and adjust for prognostic factors that might influence the outcome. In this paper...

journal_title：Breast cancer research and treatment

authors： Hastie T,Sleeper L,Tibshirani R

更新日期：1992-01-01 00:00:00

abstract：:We have previously shown that human breast carcinoma cells demonstrating an interconverted phenotype, where keratin (epithelial marker) and vimentin (mesenchymal marker) intermediate filaments are both expressed, have an increased ability to invade a basement membrane matrix in vitro. This increase in invasive potenti...

journal_title：Breast cancer research and treatment

authors： Kirschmann DA,Seftor EA,Nieva DR,Mariano EA,Hendrix MJ

更新日期：1999-05-01 00:00:00

abstract：:The purpose of this article is to comprehensively summarize the associations between carotenoids and breast cancer and quantitatively estimate their dose-response relationships. We searched PubMed, Embase, and Cochrane databases (from January 1982 to 1 May 2011) and the references of the relevant articles in English w...

journal_title：Breast cancer research and treatment

authors： Hu F,Wang Yi B,Zhang W,Liang J,Lin C,Li D,Wang F,Pang D,Zhao Y

更新日期：2012-01-01 00:00:00

abstract：:Obesity and metabolic syndrome are risk and prognostic factors for breast cancer (BC) and are associated with chronic inflammation. We investigated the association between distinct BC subtypes and markers of adiposity, dysmetabolisms, and inflammation. We analyzed 1779 patients with primary invasive BC treated at a si...

journal_title：Breast cancer research and treatment

authors： Agresti R,Meneghini E,Baili P,Minicozzi P,Turco A,Cavallo I,Funaro F,Amash H,Berrino F,Tagliabue E,Sant M

更新日期：2016-05-01 00:00:00

abstract：:About 15% of metastatic breast carcinoma patients are diagnosed with brain metastases. Historically, the majority are treated with palliative external whole-brain radiation with a median survival of 4 months. We examined stereotactic radiosurgery's effect on treatment outcome in such patients. Four hundred and fifty f...

journal_title：Breast cancer research and treatment

authors： Lederman G,Wronski M,Fine M

更新日期：2001-01-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) regulate diverse cellular processes, such as proliferation, differentiation, and apoptosis. The BMPs have been studied in several cancers, but thus far contradictory results have been obtained and, especially in breast cancer, information on BMPs is still limited. We performed a syst...

journal_title：Breast cancer research and treatment

authors： Alarmo EL,Kuukasjärvi T,Karhu R,Kallioniemi A

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To investigate the clinical impact of FDG-PET/CT for staging and treatment planning in high-risk primary breast cancer. METHODS:Women with high-risk primary breast cancer were enrolled between September 2017 and August 2019 at Odense University Hospital, Denmark. Conventional mammography with/without MRI was p...

journal_title：Breast cancer research and treatment

authors： Vogsen M,Jensen JD,Christensen IY,Gerke O,Jylling AMB,Larsen LB,Braad PE,Søe KL,Bille C,Ewertz M,Hildebrandt MG

更新日期：2021-01-01 00:00:00

abstract：:Breast cancer has emerged as the most frequent malignancy among Korean women. Its clinical features have become closer to those now observed in Western countries. We performed this study to evaluate the chronological changes in Korean breast cancer characteristics and reproductive factors from 1996 to 2004. A nationwi...

journal_title：Breast cancer research and treatment

authors： Ahn SH,Yoo KY,Korean Breast Cancer Society.

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:Estimated glomerular filtration rate (eGFR) is commonly used to calculate carboplatin doses and capping the eGFR may be used to reduce the risk of excessive dosing and toxicity. We sought to retrospectively examine the impact of our carboplatin guidelines on pathological complete response rates (pCR) and toxici...

journal_title：Breast cancer research and treatment

authors： Howell SJ,Coe F,Wang X,Horsley L,Ekholm M

更新日期：2020-11-01 00:00:00

abstract：:To increase the ability of ultrasonographic (US) technology for the differential diagnosis of solid breast tumors, we describe a novel computer-aided diagnosis (CADx) system using data mining with decision tree for classification of breast tumor to increase the levels of diagnostic confidence and to provide the immedi...

journal_title：Breast cancer research and treatment

authors： Kuo WJ,Chang RF,Chen DR,Lee CC

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:To examine the outcomes of endocrine naive patients treated with tamoxifen as initial endocrine therapy for metastatic breast cancer. Data were obtained from the long-term follow-up of two previously published randomized trials. PATIENTS AND METHODS:All patients received tamoxifen 20 mg po in a single daily do...

journal_title：Breast cancer research and treatment

authors： Kuss JT,Muss HB,Hoen H,Case LD

更新日期：1997-02-01 00:00:00

abstract：PURPOSE:To evaluate the patterns of failure, relapse-free survival and overall survival among African American breast cancer patients younger than 40 years. PATIENTS AND METHODS:We retrospectively reviewed the records of 124 African American breast cancer patients younger than 40 years who were registered with the How...

journal_title：Breast cancer research and treatment

authors： De Jesus MA,Fujita M,Kim KS,Goldson AL

更新日期：2003-03-01 00:00:00

abstract：INTRODUCTION:The incidence of breast cancer varies among women living in the Southwestern part of the US. We evaluate how body size influences breast cancer risk among these women. METHODS:Cases (n = 2,325) diagnosed with breast cancer between October 1, 1999 and May 2004 residing in Arizona, Colorado, New Mexico, or ...

journal_title：Breast cancer research and treatment

authors： Slattery ML,Sweeney C,Edwards S,Herrick J,Baumgartner K,Wolff R,Murtaugh M,Baumgartner R,Giuliano A,Byers T

更新日期：2007-03-01 00:00:00

abstract：:The androgen receptor (AR) is a transcription factor mediating the action of androgens. The AR gene is localized on chromosome X and it contains a series of CAG trinucleotide repeats. The length of the CAG repeats varies among individuals and this polymorphism is believed to be related to AR transcriptional activity. ...

journal_title：Breast cancer research and treatment

authors： Yu H,Bharaj B,Vassilikos EJ,Giai M,Diamandis EP

更新日期：2000-01-01 00:00:00

abstract：:Fibroblast growth factor receptor 2 is a tyrosine kinase receptor that is a member of the family of individually distinct fibroblast growth factor receptors involved in cell proliferation, invasiveness, motility, and angiogenesis. Genome-wide association studies have identified FGFR2 as a breast cancer (BC) susceptibi...

journal_title：Breast cancer research and treatment

authors： Jia C,Cai Y,Ma Y,Fu D

更新日期：2010-11-01 00:00:00

abstract：:Bone marrow-derived mesenchymal stem cells (MSCs) are known to specifically migrate to and engraft at tumour sites. Understanding interactions between cancer cells and MSCs has become fundamental to determining whether MSC-tumour interactions should be harnessed for delivery of therapeutic agents or considered a targe...

journal_title：Breast cancer research and treatment

authors： Martin FT,Dwyer RM,Kelly J,Khan S,Murphy JM,Curran C,Miller N,Hennessy E,Dockery P,Barry FP,O'Brien T,Kerin MJ

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The outcome of breast cancer is usually determined by multiple factors. Serum tumor necrosis factor alpha concentration has been found to be increased in the circulation of patients with malignancy. This study was designed with the aim to investigate any correlation between the serum tumor necrosis factor al...

journal_title：Breast cancer research and treatment

authors： Sheen-Chen SM,Chen WJ,Eng HL,Chou FF

更新日期：1997-05-01 00:00:00

abstract：:Trinucleotide repeat-containing 9 (TNRC9), a high mobility group chromatin-associated protein, has been implicated in breast cancer metastasis to the bone. Recently, several single nucleotide polymorphisms (SNPs) of TNRC9 were identified as novel breast cancer susceptibility loci by whole genome association studies, e...

journal_title：Breast cancer research and treatment

authors： Liang J,Chen P,Hu Z,Shen H,Wang F,Chen L,Li M,Tang J,Wang H,Shen H

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:TOP2A gene encodes topoisomerase II alpha, the direct molecular target of anthracyclines. This gene is frequently coamplified with HER2. The aims of this study were to analyse the pattern of TOP2A amplification and protein expression in relation to the molecular subgroups of breast cancers; and to define the...

journal_title：Breast cancer research and treatment

authors： Arriola E,Rodriguez-Pinilla SM,Lambros MB,Jones RL,James M,Savage K,Smith IE,Dowsett M,Reis-Filho JS

更新日期：2007-12-01 00:00:00

abstract：:Women with diabetes have higher breast cancer incidence and mortality. The purpose of this study was to examine the impact of diabetes on stage at breast cancer diagnosis, as a possible reason for their higher mortality. Using population-based health databases from Ontario, Canada, this retrospective cohort study exam...

journal_title：Breast cancer research and treatment

authors： Lipscombe LL,Fischer HD,Austin PC,Fu L,Jaakkimainen RL,Ginsburg O,Rochon PA,Narod S,Paszat L

更新日期：2015-04-01 00:00:00

abstract：:Endocrine therapy is an important therapeutic approach for the treatment of oestrogen receptor (ER)-positive breast cancer. However, a number of these endocrine therapies can fail when the tumour loses its ER expression during treatment. To date, few studies have explored the potential clinical significance of traditi...

journal_title：Breast cancer research and treatment

authors： Zhang B,Zhang X,Tang B,Zheng P,Zhang Y

更新日期：2012-11-01 00:00:00

abstract：:After more than 100 reported randomized trials of systemic adjuvant therapy in breast cancer, it is clear that this therapy will prolong the time to recurrence and the survival time significantly, at least in some patient subsets. But there is less than complete agreement as to which subsets, which therapies, how much...

journal_title：Breast cancer research and treatment

authors： Henderson IC

更新日期：1989-10-01 00:00:00