Abstract：
OBJECTIVE:To determine if women who have undergone transcervical resection of the endometrium can be treated safely with estrogens alone. METHODS:Sixty-two postmenopausal women who had undergone endometrial resection were recruited into a double-blind, randomized study. Twenty-one had menopausal symptoms at the primary operation and were recruited at the time of the surgery, and 38 were recruited an average of 20 months (range 8-42) after the primary endometrial resection and underwent a second resection to remove any residual endometrium before entering the study. Three patients were excluded from the study. Subjects were allocated randomly to one of two hormone replacement therapy (HRT) regimens: 17-beta-estradiol 2 mg alone or combined with norethisterone 1 mg. Clinical and ultrasound data were collected every 3 months. Hysteroscopically standardized endometrial biopsies were taken after 1 year. RESULTS:In the single-agent therapy group, endometrial hyperplasia without atypia was found in six subjects and proliferative endometrium in eight after 1 year. No such cases occurred among women receiving combined therapy. Endometrial thickness and menstrual bleeding were significantly greater in the single-agent therapy group than in those receiving combined therapy. These differences between single-agent and combined therapy were statistically significant. CONCLUSION:Postmenopausal HRT in patients who have undergone transcervical resection of the endometrium should include progestagen for protection of the endometrium.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Istre O,Holm-Nielsen P,Bourne T,Forman Adoi
10.1016/0029-7844(96)00308-0subject
Has Abstractpub_date
1996-11-01 00:00:00pages
767-70issue
5eissn
0029-7844issn
1873-233Xpii
0029-7844(96)00308-0journal_volume
88pub_type
临床试验,杂志文章,随机对照试验abstract：:The healing of a midfibular fracture was studied in mature rats. The strength of the healing fracture was determined by a constant speed-driven tensiometer which measured the force required to separate the healing callus. The breaking strength of the healing experimental fracture was ascertained in control, estrogen-t...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：OBJECTIVE:Diverging findings concerning the rate of postoperative wound infections in patients undergoing breast surgery have been reported, and little is known regarding the possible risk factors for these infections and their relative importance. We assessed risk factors for wound infection, placing particular emphas...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(03)00044-9
更新日期：2003-04-01 00:00:00
abstract：:A modified CEA-Roche kit was used to determine the pretreatment value of carcinoembryonic antigen (CEA) in patients with intraepithelial neoplasia and invasive squamous cell carcinoma of the cervix. A positive correlation between tumor volume and CEA levels was found in patients with invasive disease, and patients wit...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-197805000-00004
更新日期：1978-05-01 00:00:00
abstract：OBJECTIVE:We describe the current state of prevention of neonatal group B streptococcal infections and present recent advances toward the development of a maternal vaccine for prevention of this disease. DATA SOURCES:We used a MEDLINE search of the Index Medicus from 1976-1992 for articles regarding group B streptococ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1992-08-01 00:00:00
abstract：:The population of women who sell or exchange sex or intimate sexual services for material goods or services, also called "sex work," often is unrecognized in the typical obstetric and gynecologic practice. The prevalence of this behavior among adult women is difficult to quantify because of its frequent omission from ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,实务指引
doi：10.1097/AOG.0000000000002163
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVE:To evaluate whether current Joint Commission (JC) exclusion criteria for measure PC-01, "Elective Delivery" before 39 weeks of gestation, accurately identify valid, codeable indications for planned early-term delivery. METHODS:We performed a review and critical analysis of all cases recorded as noncompliant ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000059
更新日期：2014-01-01 00:00:00
abstract：:This review comprises 36 patients who were treated for Asherman's syndrome from 1968 to 1974 at the Sloane Hospital for Women. Of the 18 patients who later conceived only 6 had uncomplicated term deliveries. Four had premature deliveries resulting in neonatal death. Three had placenta accreta and postpartum hemorrhage...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-06-01 00:00:00
abstract：BACKGROUND:Double aneuploidies account for 0.21-2.8% of spontaneous abortions resulting from chromosomal abnormalities. Rarely, cell-free DNA testing detects multiple aneuploidies; however, to discern among maternal, placental, and fetal origin, further evaluation is required. CASE:A 49-year-old woman, gravida 5 para ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001390
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:To estimate the incidence of gestational diabetes mellitus (GDM) according to The International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria and the pregnancy complications in women fulfilling these criteria but who are not considered diabetic according to the Canadian Diabetes Ass...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31826994ec
更新日期：2012-10-01 00:00:00
abstract：:Delayed umbilical cord clamping appears to be beneficial for term and preterm infants. In term infants, delayed umbilical cord clamping increases hemoglobin levels at birth and improves iron stores in the first several months of life, which may have a favorable effect on developmental outcomes. There is a small increa...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,实务指引
doi：10.1097/AOG.0000000000001860
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:To determine reproductive outcomes in women with congenital uterine anomalies detected incidentally by three-dimensional ultrasound. METHODS:We studied 1089 women with no history of infertility or recurrent miscarriage who were seen for a transvaginal ultrasound scan. They were screened for uterine abnormali...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(01)01599-x
更新日期：2001-12-01 00:00:00
abstract：:Fetal oxytocin contribution to the mother during spontaneous labor was investigated using a specific and sensitive radioimmunoassay to measure oxytocin in blood, amniotic fluid, and urine. In 26 subjects with spontaneous labor and vaginal delivery (Group I) and 18 subjects with cesarean section after labor (Group II),...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1978-08-01 00:00:00
abstract：BACKGROUND:Takotsubo cardiomyopathy is a cardiac condition associated with the acute onset of chest pain, abnormalities in cardiac enzymes and electrocardiogram, and a distinct pattern of left ventricular dysfunction on echocardiography. This case evaluates an obstetric patient diagnosed with Takotsubo cardiomyopathy d...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3181662cfe
更新日期：2008-08-01 00:00:00
abstract：:Over a 63-month period beginning January 1, 1977, 258 infants with birth weights of 500-999 g were born alive at one tertiary perinatal center; 170 were offered full intensive care. The mothers of 67 (39.4%) of these 170 infants had been given betamethasone antenatally to accelerate fetal lung maturation. Of the 67 in...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：OBJECTIVE:To compare intrauterine device (IUD) use at 6 months postpartum among women who underwent intracesarean delivery (during cesarean delivery) IUD placement compared with women who planned for interval IUD placement 6 or more weeks postpartum. METHODS:In this nonblinded randomized trial, women who were undergoi...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1097/AOG.0000000000000882
更新日期：2015-07-01 00:00:00
abstract：:One hundred consecutive cases of hyperplasia of the endometrium were referred to the Sloane Hospital for Women. The referral diagnoses and consultation diagnoses were compared for the purpose of analyzing common diagnostic problems in interpretation of endometrial hyperplasias and the use of diagnostic terminology as ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-08-01 00:00:00
abstract：:Following is a report and a review of literature concerning the supernumerary ovary. Up to now only 7 cases have been reported, and our case appears to be the eighth. The anatomic situation in this case was unusual since it was found in the mesentery. Of the cases previously reported, 2 have been associated with benig...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
abstract：OBJECTIVE:To estimate the cost-effectiveness of universal group B streptococci (GBS) screening in women with a singleton pregnancy planning a repeat cesarean delivery. METHODS:We conducted a decision analysis from a health care perspective to compare the cost-effectiveness of GBS screening for women planning a repeat ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001800
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:To estimate the change in indications for scheduled deliveries during the Ohio Perinatal Quality Collaborative's initiative to decrease scheduled deliveries for nonmedical indications before 39 weeks of gestation. METHODS:Documented indications for scheduled deliveries between 36 0/7 and 38 6/7 weeks were ca...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e318260d9b2
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVE:To investigate risk factors and prevalence of anal incontinence among women with pelvic floor dysfunctions. METHODS:We evaluated 881 women with symptoms of urinary incontinence and/or genital prolapse. Each completed a bowel questionnaire and underwent a detailed medical, surgical, obstetric, and gynecologic...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(02)02215-9
更新日期：2002-10-01 00:00:00
abstract：BACKGROUND:Positron emission tomography (PET) fused with computed tomography (CT) imaging is common in the clinical assessment of patients with locally advanced cervical cancer. Limitations to the utilization and interpretation of PET-CT scans in patients with cervical cancer have been described, including false-positi...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000701
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:To hypothesize that higher intake of docosahexaenoic acid, an n-3 long chain polyunsaturated fatty acid, would increase duration of gestation and birth weight in US women. METHODS:This was a randomized, double-blind, controlled, clinical trial. Subjects were enrolled in an ambulatory clinic where they receiv...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0029-7844(02)02585-1
更新日期：2003-03-01 00:00:00
abstract：:The nonstress test is a commonly used tool for fetal well-being assessment. The antenatal death rate using the nonstress test as a primary modality is significantly higher than that with the use of the contraction stress test. The nonstress test is commonly performed on a once-a-week basis. The rate of stillbirths wit...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1986-04-01 00:00:00
abstract：BACKGROUND:Monoamniotic twin pregnancies are frequently associated with cord entanglement, but such entanglement rarely involves the co-twin's trunk, extremities, or neck. CASE:We report a set of monoamniotic twins in which color Doppler imaging revealed that the cord of twin B was wrapped around the neck of its dead ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：OBJECTIVE:To estimate the incidence and identify the risk factors for pelvic organ prolapse repair after hysterectomy. METHODS:We conducted a case-control study. We identified 6,214 women who underwent hysterectomy in our gynecology department from 1982 to 2002. Cases (n=114) were women who required pelvic organ prola...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000278567.37925.4e
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVE:To determine whether there is an association between history of sexual abuse and development of chronic pelvic pain. METHODS:We studied 36 women with chronic pelvic pain, 23 with chronic low back pain, and 20 healthy women with reference to experience of sexual abuse, physical violence, and emotional neglect...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(00)01072-3
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:Abdominal pregnancy is a rare, life-threatening variant of ectopic pregnancy, and thus its diagnosis and management remain controversial. CASE:A multigravida was admitted for complaints of abdominal swelling that had been occurring for 2 years and symptoms of pregnancy in the 3 months before admission. Radi...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31819ecc82
更新日期：2009-08-01 00:00:00
abstract：:Several authorities have recommended cesarean section for all intrapartum breech presentations. The present study documents that judiciously selected fetuses at term in breech presentation may be safely delivered vaginally by a selective management protocol that requires cesarean section when mandated criteria are not...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1980-12-01 00:00:00
abstract：:A review of 25 patients with more than 1 rubella titer by hemagglutination-inhibition testing revealed 3 patients with high positive titers that were reported to be negative in subsequent pregnancies. None of the patients had received the rubella vaccine. Because the sensitivity and reliability of hemagglutination-inh...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-08-01 00:00:00
abstract：:Amniotic fluid prostaglandin levels were measured serially in 15 patients who underwent successful induction of labor and compared with those of patients presenting in spontaneous labor. At comparable cervical dilation the induced group demonstrated significantly lower prostaglandin levels. Four of these patients deli...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1986-11-01 00:00:00
