Abstract:
:The article summarises the statistical data of bone marrow transplantation (BMT) carried out in Hungary between 1990-1995 in yearly distribution. Since the first BMT up to the end of 1995, 168 BMT were performed. The number of transplantations since 1990 to our days was gradually increasing. As a result of this activity in the three transplantation centers (National Institute of Haematology and Immunology, St. László Hospital and County Hospital in Miskolc) 36 allogeneic and 12 autologous BMT were performed in 1995. Out of the allogeneic BMT cases, 14% of them were completed with unrelated, donors in the last three years. The most frequent indications for allogenic BMT are: chronic myeloid leukaemia (CML), acute lymphoid leukaemia (ALL), acute myeloid leukaemia (AML), myelodysplasia, severe aplastic anaemia. Child allogenic BMTs are carried out on pediatric patients in St. László Hospital in leukaemia, severe aplastic anaemia cases and children born with immunodeficiency. Autologous BMTs started in an organised way in 1995 for adult patients in cases of non-Hodgkin lymphoma, Hodgkin lymphoma and for children with solid tumour indication in the Miskolc Centre. BMT activity in Hungary compared with international data, especially within Europe, shows a significant drop behind. To calculate for ten million inhabitants, the optimal BMT activity should be between 100-200 transplantations (allogeneic and autologous BMT together) in 1994. Among the Central European countries Hungary and Poland fall most behind. Autologous BMTs in most countries of Europe are above of allogeneic BMTs in numbers as indication in cases of lymphoma and solid tumours (first of all mamma carcinoma) comes into focus. This summary emphasises the most important difficulties in connection with the development of the National BMT program.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Petrányi G,Masszi T,Tímár L,Kriván G,Pálóczi K,Nagy K,Fekete S,Reményi P,Torbágyi E,Dénes R,Kelemen Esubject
Has Abstractpub_date
1996-10-06 00:00:00pages
2203-8issue
40eissn
0030-6002issn
1788-6120journal_volume
137pub_type
杂志文章相关文献
ORVOSI HETILAP文献大全abstract::The author describes some of the numerous domains regarding the new topic called "Vascular endothelial dysfunction, oxidative stress". The endothelium is responsible for the constancy and integrity of the milieu interieur by producing various substances. Endothelial dysfunction occurs when there is imbalance between v...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2008.28402
更新日期:2008-07-13 00:00:00
abstract::The authors describe in their case study the history of a 51 year old man, at whom they verified without thoracotomy thoracal actinomycosis. They achieved recovery giving permanently high doses of Penicillin. In connection with this rare case the authors review pathogenesis, the symptomatology, the diagnosis and the t...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1996-09-15 00:00:00
abstract:INTRODUCTION:The prevalence of invasive pneumococcal disease, which is depending on risk factors and comorbidities, is increasing over the age of 50 years. Most developed countries have recommendations but vaccination rates remain low. AIM:To assess the general practitioners' daily practice in relation to pneumococcal...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2015.30054
更新日期:2015-02-01 00:00:00
abstract::The authors present a case of an infant who was treated for recurrent vomiting following pyloromyotomy. Gastroscopic examination showed a polypoid tumour of 4-5 mm in diameter located at the antral region. The patient recovered following re-pyloromyotomy. ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2002-08-04 00:00:00
abstract::Epididymotomy was performed besides drug therapy in 61 patients suffering from acute epididymitis. Surgical intervention was indicated if the conservative therapy was not successful or the wall of the scrotum became fixed. Epididymotomy is carried out by longitudinal or multiple incision of the inflamed epididymis and...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1989-04-23 00:00:00
abstract:UNLABELLED:Failures in the antibiotic therapy of Lyme disease have repeatedly been demonstrated by post-treatment isolations of the infecting borreliae. Analyses of the antibiotic susceptibility patterns of borreliae may help to understand the causes of such treatment failures and to develop new therapeutic regimens. ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2002-05-26 00:00:00
abstract:INTRODUCTION AND AIM:The birth prevalence of congenital malformations is around 2-3%. The aim of this study was to examine the efficacy of ultrasound diagnostics in detecting congenital malformations. METHOD:We have processed the prenatal sonographic and postnatal clinical details of 1867 inborn abnormalities in 1200 ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2017.30911
更新日期:2017-11-01 00:00:00
abstract::This study compared the physiological and economical effects of laparoscopic and open surgery. The laparoscopic minimally invasive technique reduced the trauma of the tissue, the homeostasis of the organism was less damaged, therefore the metabolic and inflammatory responses were reduced, the respiration and blood gas...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:1997-02-02 00:00:00
abstract::Microcirculatory disorders play a major role in the development of organ failure in a variety of conditions. Perfusion changes may be visualized by static and dynamic methods, with direct and indirect techniques. Orthogonal polarization spectral imaging is a novel method of imaging the human microcirculation. The tech...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2001-05-27 00:00:00
abstract:INTRODUCTION:Lower limbs anatomical and biomechanical parameters are essential in several paediatric orthopaedic disease, which makes their exact measurement necessary. AIM:The aim of the author was to evaluate the reliability of the EOS 2D/3D System, a 3D reconstruction capable imaging device in children. METHOD:3D ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2014.30009
更新日期:2014-10-26 00:00:00
abstract::Compression of the rostral ventrolateral medulla oblongata is one of the rarely identified causes of refractory hypertension. In patients with severe, intractable hypertension caused by neurovascular compression, neurosurgical decompression should be considered. The authors present the history of a 20-year-old man wit...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2014.29908
更新日期:2014-05-25 00:00:00
abstract::Malignant tumours often display hypoxic tissue areas where the oxygen tension is < 7 mm Hg. Studies in this field have proved that the hypoxic state boosts tumour progression and aggressive behaviour. In tissue culture experiments "in vitro" oxygenation was found to inhibit in itself the proliferation of cells of heal...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2007.28024
更新日期:2007-07-29 00:00:00
abstract::We report the successful surgical removal of a large floating thrombus from the ascending aorta causing systemic embolization. It was diagnosed by transesophageal echocardiography (TEE), CT scan, aortography and Cardiovascular Magnetic Resonance Imaging (CMR). The free-floating, highly embolic source 2 cm distal to th...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/OH.2007.27975
更新日期:2007-02-25 00:00:00
abstract::Authors describe two cases of lead poisoning of unusual origin. A 43 year old male patient bought some waste metal in order to build a fence around his new house for saving money. He removed the old corroded coat of paint using a grinder without any protection. Consequently, he had got grave lead intoxication with col...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1997-11-02 00:00:00
abstract:INTRODUCTION:Outcome of arterial switch operation for transposition of the great arteries with/without ventricular septal defect is a service key-performance-indicator. AIM:The aim of the authors was to assess patient characteristics and parameters in the perioperative course. METHOD:In the setting of a newly-establi...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2015.30176
更新日期:2015-06-21 00:00:00
abstract::Clinical data of 34 patients with DM, who have been treated during the years 1971 and 1998 were evaluated. 79% of the patients (27 patients) were female, 21% of them (7 patients) were male. 59% of the patients (20 pts) were between the ages of 41 and 50 years. The characteristic heliotrop rash were observed in 26 pati...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2000-01-30 00:00:00
abstract::Since the eighties of the last century hormone content was justified in immune cells (lymphocytes, granulocytes, monocytes, macrophages and mast cells), which produce, store and secrete these hormones. Although the amount of these materials in immune cells is relatively small, the mass of the producers (immune cells) ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2011.29122
更新日期:2011-05-15 00:00:00
abstract:INTRODUCTION:Early diagnosis of sex chromosome abnormalities is important because of prevention, family planning and optimal therapy. AIM:Investigation of the relationship between phenotype, age at time of diagnosis and therapeutic options in sex chromosome aberrations. METHOD:Processing data of 51 children with sex ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2018.31081
更新日期:2018-07-01 00:00:00
abstract::Among the several eye diseases (or diseases involving the eye) based on hypersensitivity reactions, the most frequent is allergic conjunctivitis. Recently six types of allergic conjunctivitis/keratoconjunctivitis are distinguished: 1. seasonal, 2. perennial, 3. vernal, 4. giant papillary, 5. atopic and 6. of contact o...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2000-08-20 00:00:00
abstract::In the report on 35 CT-guided fine needle transthoracic biopsies the authors show the relevance of invasive radiological methods in tumor diagnostics. The results are compared with those published in the literature. CT-guided transthoracic biopsy is of crucial importance in final diagnosis of certain thoracic diseases...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1993-06-27 00:00:00
abstract::Összefoglaló. A malignus csonttumorok sebészi ellátása során kialakuló szegmentális csontdefektusok pótlása fontos szempont a végtagmegtartó sebészetben. Felnőttkorban a megoldás rendszerint tumorprotézis beültetése, 10 évesnél fiatalabb gyermekeknél azonban ez nehezen alkalmazható módszer a kis csontméret és az igen ...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2020.31767
更新日期:2020-11-08 00:00:00
abstract::The number of chloroquine-resistant Pl. falciparum malaria cases in the last decade dramatically increased. This fact causes significant problems not only in the therapy but in the malaria chemoprophylaxis as well. Presently, in accordance with the WHO's recommendations, the drug of choice in the malaria chemoprophyla...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1994-01-30 00:00:00
abstract::Free radicals which are produced constantly in the human body have a significant role in the development of atherosclerosis. The responsibility of leukocytes for vascular disease has been proved in several ways. Hormonally active women are protected much more against myocardial infarction than men, which fact can be e...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1999-07-18 00:00:00
abstract::Although an impressive progress has been achieved in the treatment of cardiovascular diseases, they are at the top of the mortality statistics in Hungary. Prevention of these diseases is an essential task of the primary health care. Cardiovascular prevention is carried out at primary, secondary and tertiary levels usi...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2012.29442
更新日期:2012-09-30 00:00:00
abstract::Introduction: The organized breast and cervical screening programs were implemented in the framework of public health program in Hungary in order to reduce breast cancer mortality by 30% and cervical cancer mortality by 60% in given age groups within 10 years by 2012. Aim: The aim of our study was to conduct a retrosp...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:10.1556/650.2019.31518
更新日期:2019-12-01 00:00:00
abstract::The case history of a 49-year-old female patient is reported, who was operated on because of varicose vein in the left lower extremity. A few days after the operation serious signs of cerebrovascular insult appeared. The clinical picture and the result of an urgent transoesophageal echocardiography are described; a se...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:2000-07-02 00:00:00
abstract::In the past decade several novel findings point to the critical role of the skeleton in several homeostatic processes, including energy balance. The connection begins in the bone marrow with lineage allocation of mesenchymal stem cells to adipocytes or osteoblasts. Osteoblasts and adipocytes produce factors affecting ...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:10.1556/OH.2011.29147
更新日期:2011-07-17 00:00:00
abstract::(-)-Deprenyl, the irreversible inhibitor of monoamine oxidase B, has been used for decades in the therapy of Parkinson's disease. It improves parkinsonian symptoms due to its dopamine potentiating and antioxidant properties and presumedly delays disease progression. Its complex pharmacological action cannot be explain...
journal_title:Orvosi hetilap
pub_type: 杂志文章,评审
doi:
更新日期:2006-07-09 00:00:00
abstract::Kabuki syndrome is characterised by a peculiar face resembling the make-up of actors in Kabuki, the traditional Japanese theatre, postnatal growth deficiency, mild to moderate mental retardation, unusual dermatoglyphic patterns, and various skeletal and visceral anomalies. The author would like to draw attention to th...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-08-20 00:00:00
abstract::The possible role of of the marked changes in the regulation of female sex hormones has been implicated in the higher prevalence rate of anxiety and affective disorders in women. There is no evidence, however, for a direct relationship between specific hormone alterations and psychiatric, nosologic entities in the cri...
journal_title:Orvosi hetilap
pub_type: 杂志文章
doi:
更新日期:1995-02-19 00:00:00