Abstract:
BACKGROUND:Diverticulitis is a common indication for surgical emergency room admission, often leading to abdominal computed tomography (CT) scanning for both diagnosis and staging. C-reactive protein (CRP) has been identified as a useful biomarker of inflammation. Aspirin and corticosteroids are known to down-regulate CRP production. In this study, we evaluated the usefulness of CRP as a biomarker for complicated diverticulitis and specifically in patients on anti-inflammatory medications: aspirin and corticosteroids. METHODS:We analyzed the medical records of patients diagnosed at one medical center during a two-year period, with left-sided diverticulitis, according to clinical data and CT scan. Disease severity was assessed by the Hinchey score using the radiological findings detected by CT. RESULTS:A total of 295 patients were included in the study. Two hundred and forty-three (82 %) were classified with uncomplicated (Hinchey 1a) and 52 (18 %) with complicated disease (Hinchey > 1a). Mean CRP levels were 133.5 and 63.5 mg/ml for those with complicated and uncomplicated disease, respectively (p < 0.001), and 139 and 60 mg/ml, respectively (p < 0.001) in the subgroup of patients taking aspirin (n = 61). For 14 patients on corticosteroid treatment, the difference in mean CRP levels for complicated and uncomplicated disease was not statistically significant. CRP > 90 mg/ml had 88 % sensitivity and 75 % specificity for complicated disease. CONCLUSIONS:The CRP level distinguished between complicated and uncomplicated disease among left-sided diverticulitis patients including those taking aspirin, but not among those on corticosteroid treatment.
journal_name
Tech Coloproctoljournal_title
Techniques in coloproctologyauthors
Nizri E,Spring S,Ben-Yehuda A,Khatib M,Klausner J,Greenberg Rdoi
10.1007/s10151-013-1044-5subject
Has Abstractpub_date
2014-02-01 00:00:00pages
145-9issue
2eissn
1123-6337issn
1128-045Xjournal_volume
18pub_type
杂志文章abstract::After pelvic pouch surgery (restorative proctocolectomy), periodic or continuous diarrhea is common. Distressing diarrhea may be triggered by pouchitis, cuffitis or an anastomotic stricture. Medical therapy with loperamide or diphenoxylate is often unsatisfactory even after the correction of the underlying problem. Se...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-006-0306-x
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:A prospective randomized trial to assess the cleansing ability and tolerance of bowel preparations for colonoscopy was conducted in a group of 953 patients. METHODS:The bowel cleansing methods were: sennoside calcium, polyethylene glycol (PEG) lavage, oral sodium phosphate (NaP) in one 90-ml dose, oral NaP ...
journal_title:Techniques in coloproctology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-04-01 00:00:00
abstract::Colorectal cancer (CRC) is the second leading cause of cancer-related morbidity and mortality in Europe and the United States. Planning for a CRC screening began in co-operation with local authorities (Pella Prefecture sponsored test kits). Our aims were to develop a screening programme for colorectal cancer using the...
journal_title:Techniques in coloproctology
pub_type: 临床试验,杂志文章,随机对照试验
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abstract:BACKGROUND:Various predictors of perioperative risk for patients with rectal cancer undergoing radical resection have been well described, but no simple scoring system for surgeons to estimate this risk currently exists. The objective of this study was to develop a system for more accurate preoperative evaluations of c...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
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abstract:BACKGROUND:Patient self-report is important in the assessment of the impact of anal incontinence (AI) on quality of life. This study aimed to (1) determine the correlation between total St. Mark's Incontinence Score (SMIS) and a single-item visual analogue scale (VAS) for bother from AI, and (2) determine the correlati...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-015-1397-z
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Obstetric anal sphincter injury is the most frequent cause of fecal incontinence (FI) in young women. However, the relationship between the extent of anal sphincter defects and the severity of long-term FI (at least 1 year after delivery) has been poorly studied. The aim of the present study was to determine...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
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journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s101510170001
更新日期:2001-08-01 00:00:00
abstract::Retained rectal foreign body is not an uncommon condition, but reliable epidemiological data are not available. The diagnosis and management can present a significant challenge due to delayed presentation and the reluctance of the patients to provide details of the incident. The aim of the clinical evaluation is to id...
journal_title:Techniques in coloproctology
pub_type: 杂志文章,评审
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journal_title:Techniques in coloproctology
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更新日期:2020-10-01 00:00:00
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journal_title:Techniques in coloproctology
pub_type: 杂志文章
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更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Although the Hinchey scoring system has guided surgical decision making for perforated diverticulitis, what constitutes optimal surgical management is controversial. We report our experience of selective primary closure of the perforation without use of a transverse colostomy and the specific circumstances i...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-011-0675-7
更新日期:2011-06-01 00:00:00
abstract::Recto-urinary, recto-vaginal and ileo-anal pouch-associated fistulae are rare yet a significant clinical problem due to their profound impact on patients' quality of life and are a challenge to repair. In this report, we describe repair of these complex fistulae using a modified trans-sphincteric posterior sagittal ap...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-012-0917-3
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Preoperative staging of rectal tumours is considered essential to tailoring treatment for individual patients. The aim of the present study was to evaluate the accuracy of 3-D-endorectal ultrasonography for the preoperative staging of rectal cancer. METHODS:Three hundred and fifty-seven patients with rectal...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-004-0099-8
更新日期:2004-11-01 00:00:00
abstract::Peripheral neuropathy associated with anesthesia is a significant source of morbidity and the second most frequent cause of professional liability in anesthetic practice. Nerve injuries are a well-recognised complication of anesthesia. Brachial plexus neuropathy is a rare syndrome with an incidence of 1.6 cases per 10...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-005-0212-7
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:The differences between the costs of robotic rectal resection and of the laparoscopic approach are still not well known. The aim of this study was to evaluate the cost-effectiveness of robotic versus laparoscopic surgery. METHODS:We conducted an observational, comparative, prospective, non-randomized study ...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-020-02151-7
更新日期:2020-03-01 00:00:00
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journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-011-0695-3
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Epidemiological studies in Western countries have documented an increase of hospitalizations for acute diverticulitis (AD) but Italian evidence is scarce. The aim of the present study was to analyse the trend in hospitalization for AD, including in-hospital mortality, in Italy from 2008 to 2015. METHODS:Thr...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-018-1840-z
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:This study was performed to determine impact of open and hand-assisted colorectal resection on surgical site infection (SSI) rates. METHODS:National Surgical Quality Improvement Project data from 2006 to 2008 were supplemented with an institutional review board-approved chart review. Primary endpoint was SSI r...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
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更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Ileal pouch-anal anastomosis (IPAA) for ulcerative colitis(UC) can be performed as either 2- or 3-stage procedure. IPAA in the elderly has been reported as safe and feasible, but little work to date has assessed outcomes by procedure. The aim of our study was to assess use and short-term outcomes of 2- and 3...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
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journal_title:Techniques in coloproctology
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更新日期:2019-04-01 00:00:00
abstract::Colorectal cancer (CRC) is the leading cause of cancer-related mortality in western countries. Adjuvant treatment does not seem to be highly effective and recurrent or metastatic disease occurs in half of the new cases within one year of diagnosis and median survival does not exceed 18 months. CRC represents an optima...
journal_title:Techniques in coloproctology
pub_type: 杂志文章,评审
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更新日期:2004-12-01 00:00:00
abstract::Advancements in the medical treatment of Crohn's disease have reduced the need for surgery. The indications for surgery include the failure of medical management, especially the persistence or worsening of symptoms in spite of proper treatment and complications of the disease process. These complications include intes...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-011-0728-y
更新日期:2011-10-01 00:00:00
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journal_title:Techniques in coloproctology
pub_type: 杂志文章
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更新日期:2020-08-27 00:00:00
abstract:BACKGROUND:The new da Vinci Single-Port (SP) robot is a single-arm four-channel robotic system well suited for endoluminal surgery. We report our initial experience performing SP robotic transanal minimally invasive surgery (SP rTAMIS) for rectal neoplasms. METHODS:Under Institutional Review Board approval, two patien...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
doi:10.1007/s10151-020-02358-8
更新日期:2020-10-17 00:00:00
abstract:INTRODUCTION:One in ten patients with rectal cancer presents with synchronous colorectal liver metastases. We present an up-to-date review of the different surgical strategies available for rectal cancer patients with synchronous colorectal liver metastases. METHOD:A literature review of MEDLINE, Cochrane and Google s...
journal_title:Techniques in coloproctology
pub_type: 杂志文章,评审
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更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Conventional abdominoperineal excision (APE) of the rectum is associated with higher circumferential resection margin (CRM) involvement, increased local recurrence, and reduced survival compared to anterior resection. A more radical extralevator APE (ELAPE) technique may improve oncological outcome. However,...
journal_title:Techniques in coloproctology
pub_type: 杂志文章
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更新日期:2012-10-01 00:00:00
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journal_title:Techniques in coloproctology
pub_type: 杂志文章,随机对照试验
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更新日期:2006-07-01 00:00:00
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journal_title:Techniques in coloproctology
pub_type: 杂志文章
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更新日期:2017-09-01 00:00:00
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journal_title:Techniques in coloproctology
pub_type: 杂志文章
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更新日期:2013-10-01 00:00:00