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Juvenile hemangioma of the testis: analysis of expression of angiogenic factors.

Abstract：

:We present a case of juvenile hemangioma of the testis associated with hemangiomas of the liver and skin. The testicular hemangioma appeared to progress after therapy with interferon alpha-2a (IFN alpha-2a), whereas the liver and skin hemangiomas regressed. Analysis of growth factors responsible for proliferation of hemangioma revealed that the tumor expressed vascular endothelial growth factor but not basic fibroblast growth factor (bFGF), which is reported to be inhibited by IFN alpha-2a. This finding suggests that a possible explanation for the inadequate efficacy of IFN alpha-2a for testicular hemangioma is a lack of bFGF expression.

journal_name

Urology

journal_title

Urology

authors

Uchida K,Takahashi A,Miyao N,Takeda K,Tsutsumi H,Satoh M,Tsukamoto T

doi

10.1016/S0090-4295(96)00439-6

subject

Has Abstract

pub_date

1997-02-01 00:00:00

pages

285-6

issue

2

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(96)00439-6

journal_volume

49

pub_type

杂志文章

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