Abstract:
OBJECTIVE:To determine the utilization rate of second-trimester genetic sonogram and its role in influencing the decision for amniocentesis in women at increased risk for fetal trisomy 21. METHODS:From November 1, 1993, to December 31, 1996, a second-trimester genetic sonogram or only genetic amniocentesis (as a first choice) were offered to pregnant women referred to our institution who were at increased risk for fetal trisomy 21. RESULTS:During the study period, 2089 women were referred to our unit for genetic prenatal diagnosis; of these, 1426 (68%) chose only genetic amniocentesis, and 663 (32%) chose a genetic sonogram as their first option. The yearly utilization rates of genetic sonogram were two of 477 or 0.4% for 1993, 82 of 495 or 16.6% for 1994, 251 of 523 or 48.0% for 1995, and 328 of 594 or 55.2% for 1996. Adjusting for potential confounders, multivariable logistic regression analysis showed that the most important factors associated with the women's decision to undergo genetic amniocentesis were three or more ultrasound markers present (relative risk [RR] 189.5, 95% confidence interval [CI] 37.1, 980.0), two ultrasound markers present (RR 47.2, 95% CI 9.8, 267.8), one ultrasound marker present (RR 12.7, 95% CI 5.5, 29.7), and abnormal serum biochemistry (RR 3.0, 95% CI 1.0, 8.9). CONCLUSION:The increasing utilization trend, in conjunction with the fact that an abnormal sonogram was the most influential factor in women's decision to undergo genetic amniocentesis, suggests that genetic sonogram services for detection of trisomy 21 should be added to the armamentarium of all prenatal diagnostic centers.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Vintzileos AM,Guzman ER,Smulian JC,McLean DA,Ananth CVdoi
10.1016/S0029-7844(97)00227-5subject
Has Abstractpub_date
1997-08-01 00:00:00pages
187-90issue
2eissn
0029-7844issn
1873-233Xpii
S0029-7844(97)00227-5journal_volume
90pub_type
杂志文章abstract:OBJECTIVE:To compare the efficacy and acceptability of same-day misoprostol and overnight laminaria for cervical ripening before early second-trimester surgical abortion. METHODS:We performed a randomized, double-blinded, controlled trial comparing 400 microg of vaginal misoprostol, given 3-4 hours preoperatively, wit...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/01.AOG.0000168629.17326.00
更新日期:2005-08-01 00:00:00
abstract::To study time trends in maternal mortality in the United States and to attempt to compare the risk of cesarean with vaginal delivery, information from the Professional Activities Study of the Commission on Professional and Hospital Activities for 3 years-1970, 1974, and 1978-was reviewed. For all deliveries, mortality...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(96)00381-x
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:To evaluate dynamic fluoroscopy of the pelvic floor for the study of women with pelvic floor disorders. METHODS:In a prospective, observational study in a tertiary care referral center, 30 women with prolapse beyond the introitus underwent comprehensive fluoroscopic imaging of the pelvic floor. RESULTS:Dyna...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e31823bf978
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To examine racial differences in hormone replacement therapy (HRT) use by analyzing the relative risks and rates of HRT prescriptions for black and white women. METHODS:Data on visits to hospital outpatient departments and office-based physicians by black and white women aged 45-64 years were obtained from 2...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(98)00540-7
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:To estimate whether excessive weight gain or obesity are risk factors affecting success for vaginal birth after cesarean (VBAC). METHODS:Patients attempting VBAC were identified by the International Classification of Diseases, 9th Revision, codes "VBAC" and "non-primary C-section" and by reviewing logbooks o...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000177972.32941.65
更新日期:2005-10-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000002142
更新日期:2017-08-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1984-06-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000003360
更新日期:2019-08-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(00)01038-3
更新日期:2000-12-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000165268.09352.ed
更新日期:2006-02-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000002254
更新日期:2017-10-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1988-06-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 评论,杂志文章
doi:10.1097/AOG.0000000000001209
更新日期:2015-12-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000267318.56856.2a
更新日期:2007-06-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e3182a6ad9f
更新日期:2013-10-01 00:00:00
abstract::Amniotic fluid (AF) was measured in 511 post-dates pregnancies (at least 41 weeks of gestational age) with the use of the AF index. Ultrasonographic evaluations were conducted on a semiweekly basis. Only patients with reliable gestational ages calculated from certain last menstrual period and confirmed by early sonogr...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 评论,杂志文章
doi:10.1097/AOG.0000000000003129
更新日期:2019-03-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1097/AOG.0b013e31818bba31
更新日期:2008-11-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章,meta分析
doi:10.1097/AOG.0000000000003105
更新日期:2019-03-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000001852
更新日期:2017-02-01 00:00:00