Do ion levels in metal-on-metal hip resurfacing differ from those in metal-on-metal THA at long-term followup?

Abstract:

BACKGROUND:Metal-on-metal hip resurfacing arthroplasty (MOM HR) has become an established alternative to traditional metal-on-metal total hip arthroplasty (MOM THA) for younger, more active patients. Nevertheless, concerns remain regarding wear and corrosion of the bearing surfaces and the resulting systemic metal ion distribution. QUESTIONS/PURPOSES:We therefore asked whether (1) serum ion concentrations in patients with MOM HR at the time of long-term followup were higher than concentrations in a control population with no hip implants; (2) the ion concentrations in patients with MOM HR were different from those in patients with MOM THA; and (3) sex would influence ion levels with regard to implant type. METHODS:The MOM HR and MOM THA groups consisted of 25 patients (evaluated at a minimum of 96 months) and 16 patients (evaluated at a minimum of 106 months), respectively. Forty-eight healthy donors were recruited for reference values. Cobalt, chromium, nickel, and molybdenum were measured by furnace graphite atomic absorption spectrophotometry. RESULTS:Ion concentrations of cobalt, chromium, and molybdenum in MOM HR were higher than in controls. Chromium and cobalt release were higher in MOM HR than in MOM THA. The sex-based analysis showed the difference was because women had higher concentrations in the MOM HR group than in the MOM THA group, whereas there was no difference between the men in the two groups. CONCLUSIONS:In MOM HR, high metal ion release persists for the long term. Consequently, it is important to implement strict biomonitoring for patients who have received these implants. The sustained high levels of chromium in females within the MOM HR group are concerning and merits strong consideration when choosing implants in this patient group.

journal_name

Clin Orthop Relat Res

authors

Savarino L,Cadossi M,Chiarello E,Baldini N,Giannini S

doi

10.1007/s11999-013-2981-z

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

2964-71

issue

9

eissn

0009-921X

issn

1528-1132

journal_volume

471

pub_type

杂志文章
  • Treatment of spondylolisthesis and spondylolysis in children.

    abstract::There are 2 fairly common types of spondylolisthesis in children - dysplastic and isthmic. The dysplastic type is secondary to congenital defects at the lumbosacral joint. The isthmic is usually due to a fatigue fracture of the pars interarticularis but there is also an hereditary element in this type. Most children w...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Wiltse LL,Jackson DW

    更新日期:1976-06-01 00:00:00

  • Ketorolac prophylaxis against heterotopic ossification after hip replacement.

    abstract::Three hundred three patients undergoing total hip replacement were enrolled in a prospective, randomized, double-blind clinical study of heterotopic bone formation. All the procedures were primary arthroplasties done for osteoarthritis using an anterolateral approach. Patients with spondyloarthropathy, previous surger...

    journal_title:Clinical orthopaedics and related research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Pritchett JW

    更新日期:1995-05-01 00:00:00

  • Growth plate matrix vesicle biogenesis. The role of intracellular calcium.

    abstract::Isolated bovine growth plate chondrocytes suspended in a synthetic cartilage buffer containing 10(-7) to 10(-3) M concentrations of calcium were treated with 1 microM ionomycin to induce changes in intracellular ionized calcium as measured by Fura-2 fluorescence. An increase in intracellular calcium of 10(-6) to 10(-4...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Iannotti JP,Naidu S,Noguchi Y,Hunt RM,Brighton CT

    更新日期:1994-09-01 00:00:00

  • Do first-generation highly crosslinked polyethylenes oxidize in vivo?

    abstract:BACKGROUND:Highly crosslinked and thermally treated polyethylenes were clinically introduced to reduce wear and osteolysis. Although the crosslinking process improves the wear performance, it also introduces free radicals into the polymer that can subsequently oxidize. Thermal treatments have been implemented to reduce...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-010-1728-3

    authors: MacDonald D,Sakona A,Ianuzzi A,Rimnac CM,Kurtz SM

    更新日期:2011-08-01 00:00:00

  • Pediatric foot fractures.

    abstract::Fractures of the foot in children usually have a good prognosis and generally are treated nonoperatively. Displaced fractures of the talus and calcaneus and tarsometatarsal dislocations are rare in children and their outcome is generally good in the younger child. Older adolescents with these injuries need treatment s...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/01.blo.0000156451.40395.fc

    authors: Ribbans WJ,Natarajan R,Alavala S

    更新日期:2005-03-01 00:00:00

  • C7--T1 bilateral facet dislocation: a rare lesion presenting with the syndrome of acute anterior spinal cord injury.

    abstract::Dislocation of the cervicothoracic junction, between the C7 and T1 vertebrae, occurred in a 46-year-old inebriated man. The C7--T1 junction is difficult to visualize on roentgenographs even when the upper extremities are pulled down. This injury is uncommon and often undiagnosed immediately after injury (Fig. 7). The ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Pick RY,Segal D

    更新日期:1980-07-01 00:00:00

  • Posterior cervical fixation for fracture and degenerative disc disease.

    abstract::There are numerous newer techniques that have been developed for the internal fixation of the cervical spine in recent years. Wiring techniques are still appropriate for posterior stabilization of the cervical spine. The halo vest is still widely used for the conservative management of cervical fractures and for posto...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:

    authors: An HS,Coppes MA

    更新日期:1997-02-01 00:00:00

  • Risk factors for pulmonary emboli after total hip or knee arthroplasty.

    abstract::Because it is difficult to predict which patients may sustain a pulmonary embolism after total hip or knee arthroplasty, we assessed multiple thrombophilic and hypofibrinolytic parameters to identify risk factors. Twenty-nine patients who survived a known pulmonary embolism after total knee or total hip arthroplasty w...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/01.blo.0000128971.35014.31

    authors: Mont MA,Jones LC,Rajadhyaksha AD,Shuler MS,Hungerford DS,Sieve-Smith L,Wang P,Cordista AG,Glueck CJ

    更新日期:2004-05-01 00:00:00

  • Patient selection criteria for periacetabular osteotomy or rotational acetabular osteotomy.

    abstract:BACKGROUND:Hip dysplasia is the most common cause of secondary osteoarthritis (OA). Periacetabular osteotomy (PAO) or rotational acetabular osteotomy (RAO) has been used as a joint-preserving procedure. However, the patient selection criteria are not clearly defined. QUESTIONS/PURPOSES:Based on a systematic review, we...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1007/s11999-012-2516-z

    authors: Yasunaga Y,Yamasaki T,Ochi M

    更新日期:2012-12-01 00:00:00

  • VKORC1 variant genotypes influence warfarin response in patients undergoing total joint arthroplasty: a pilot study.

    abstract:UNLABELLED:Warfarin dosing algorithms do not account for genetic mutations that can affect anticoagulation response. We retrospectively assessed to what extent the VKORC1 variant genotype would alter the likelihood of being a hyperresponder or hyporesponder to warfarin in patients undergoing total joint arthroplasty. W...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-008-0641-5

    authors: González Della Valle A,Khakharia S,Glueck CJ,Taveras N,Wang P,Fontaine RN,Salvati EA

    更新日期:2009-07-01 00:00:00

  • Evaluation and classification of shoulder instability. With special reference to examination under anesthesia.

    abstract::Increasing knowledge of instability in the shoulder has created a more complex evaluation sequence. The history continues to be important. Many physical examination maneuvers are available to further define the problem. Routine roentgenographic examination has been extended to include views specifically designed to de...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:

    authors: Cofield RH,Irving JF

    更新日期:1987-10-01 00:00:00

  • Self-assembled monolayer films of phosphonates for bonding RGD to titanium.

    abstract::Modification of the implant surface with the Arg-Gly-Asp tripeptide (RGD) putatively facilitates osteoblast attachment for improved implant fixation in the laboratory. We compared the histomorphometric and mechanical performance of titanium implants coated with RGD using a novel interface of self-assembled monolayers ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-008-0117-7

    authors: Heijink A,Schwartz J,Zobitz ME,Nicole Crowder K,Lutz GE,Sibonga JD

    更新日期:2008-04-01 00:00:00

  • Validation of cDNA microarray analysis to distinguish tumor type ex vivo.

    abstract::Tissue biopsy alone is diagnostic in less than 10% of cases of metastatic bone disease with an unknown primary tumor. Accordingly, to delineate the neoplastic process in cases of metastatic bone disease, where the primary tumor cannot be determined with conventional modalities, new tools are attractive. Complementary ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/01.blo.0000093060.96273.db

    authors: Randall RL,Wade M,Albritton KH,Coffin CM,Joyner DE

    更新日期:2003-10-01 00:00:00

  • Cementless acetabular replacement in the young. A 5- to 10-year prospective study.

    abstract::This article presents a prospective clinical and radiologic review of 55 total hip replacements in 50 patients in which the cementless Harris-Galante porous-coated acetabular component was used. All patients were 50 years of age or younger. The cups were inserted by 15 different surgeons. The minimum followup was 5 ye...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200007000-00021

    authors: Dunkley AB,Eldridge JD,Lee MB,Smith EJ,Learmonth ID

    更新日期:2000-07-01 00:00:00

  • What Are the Frequency, Associated Factors, and Mortality of Amputation and Arthrodesis After a Failed Infected TKA?

    abstract:BACKGROUND:For patients with failed surgical treatment of an infected TKA, salvage operations such as arthrodesis or above-knee amputation (AKA) may be considered. Clinical and institutional factors associated with AKA and arthrodesis after a failed TKA have not been investigated in a large-scale population, and the ut...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-017-5285-x

    authors: Son MS,Lau E,Parvizi J,Mont MA,Bozic KJ,Kurtz S

    更新日期:2017-12-01 00:00:00

  • Semitendinosus anatomic reconstruction for cruciate ligament insufficiency.

    abstract::Semitendinosus anatomic reconstruction (STAR) rebuilds the major anatomic bands of the anterior cruciate ligament (ACL) and provides isometric ligamentous relationships. STAR secures a graft firmly enough to allow intraoperative testing and early motion. It provides a graft comparable in strength with a normal ACL and...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Mott HW

    更新日期:1983-01-01 00:00:00

  • Arthritis and arthrodesis of the hindfoot.

    abstract::Arthritic involvement of the subtalar, talonavicular, and calcaneocuboid joints is a common cause of pain in the mature hindfoot. Inflammatory, degenerative, and crystalline forms of arthritis may lead to deformity and instability of joints. When medical and nonoperative management fails, painful joints are stabilized...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/00003086-199804000-00011

    authors: Donatto KC

    更新日期:1998-04-01 00:00:00

  • Which patients are at risk for kidney dysfunction after hip fracture surgery?

    abstract:BACKGROUND:Kidney dysfunction (KD) after hip fracture surgery is a major complication. However, the incidence and risk factors of KD in this population are unclear. QUESTIONS/PURPOSES:We therefore (1) determined the incidence of KD in a large cohort of fracture patients, (2) identified preoperative risk factors predis...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-013-3098-0

    authors: Macheras GA,Kateros K,Koutsostathis SD,Papadakis SA,Tsiridis E

    更新日期:2013-12-01 00:00:00

  • Lower-limb proprioception in above-knee amputees.

    abstract::A proprioception measurement system was designed and constructed to evaluate lower-limb knee joint proprioception in ten above-knee amputees. The system permitted the testing of subjects in a position simulating late swing phase of gait. The threshold for detection of slow passive motion and the ability to reproduce s...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Eakin CL,Quesada PM,Skinner H

    更新日期:1992-11-01 00:00:00

  • High Risk of Symptomatic Venous Thromboembolism After Surgery for Spine Metastatic Bone Lesions: A Retrospective Study.

    abstract:BACKGROUND:Cancer and spinal surgery are both considered risk factors for venous thromboembolism (VTE). However, the risk of symptomatic VTE for patients undergoing surgery for spine metastases remains undefined. QUESTIONS/PURPOSES:The purposes of this study were to: (1) identify the proportion of patients who develop...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/CORR.0000000000000733

    authors: Groot OQ,Ogink PT,Paulino Pereira NR,Ferrone ML,Harris MB,Lozano-Calderon SA,Schoenfeld AJ,Schwab JH

    更新日期:2019-07-01 00:00:00

  • What Is the Adverse Event Profile After Prophylactic Treatment of Femoral Shaft or Distal Femur Metastases?

    abstract:BACKGROUND:Prophylactic surgical treatment of the femur is commonly offered to patients with metastatic disease who have a high risk of impending pathologic fracture. Prophylactic fixation is associated with improved functional outcomes in appropriate patients selected based on established criteria, but the perioperati...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/CORR.0000000000000489

    authors: McLynn RP,Ondeck NT,Grauer JN,Lindskog DM

    更新日期:2018-12-01 00:00:00

  • Partial rupture of the distal biceps tendon.

    abstract::Partial rupture of the distal biceps tendon is a relatively rare event, and various degrees of partial tendon tears have been reported. In the current study four patients with partial atraumatic distal biceps tendon tears (mean age, 59 years; range, 40-82 years) are reported. In all four patients, a common clinical pa...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200005000-00018

    authors: Dürr HR,Stäbler A,Pfahler M,Matzko M,Refior HJ

    更新日期:2000-05-01 00:00:00

  • Unexpected absence of effect of rhBMP-7 on distraction osteogenesis.

    abstract::We asked whether locally applied rhBMP-7 with a Type I collagen carrier could enhance the consolidation phase in distraction osteogenesis. We performed unilateral transverse osteotomy of the tibia in 28 immature male rabbits. In half the animals (14 rabbits), 70 microg rhBMP-7 (28.5 mg rhBMP-7/CC, OP-1) was applied lo...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/BLO.0b013e31802f1973

    authors: Sailhan F,Chotel F,Chousta A,Viguier E,Boivin G

    更新日期:2007-04-01 00:00:00

  • Radiographic anatomy of the hindfoot.

    abstract::Lead markers were placed on various osseous structures of the talus and calcaneus in fresh amputation specimens to analyze the radiographic anatomy of the hindfoot. Analysis of the talocalcaneal articulations revealed that only the central one-third of the posterior subtalar joint can be visualized on the lateral proj...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Shereff MJ,Johnson KA

    更新日期:1983-07-01 00:00:00

  • What Risk Factors Are Associated With Musculoskeletal Injury in US Army Rangers? A Prospective Prognostic Study.

    abstract:BACKGROUND:Musculoskeletal injury is the most common reason that soldiers are medically not ready to deploy. Understanding intrinsic risk factors that may place an elite soldier at risk of musculoskeletal injury may be beneficial in preventing musculoskeletal injury and maintaining operational military readiness. Findi...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-015-4342-6

    authors: Teyhen DS,Shaffer SW,Butler RJ,Goffar SL,Kiesel KB,Rhon DI,Williamson JN,Plisky PJ

    更新日期:2015-09-01 00:00:00

  • Lateral unicompartmental knee arthroplasty through a lateral parapatellar approach has high early survivorship.

    abstract:BACKGROUND:The literature suggests lateral unicompartmental knee arthroplasties are associated with low revision rates. However, there are fewer reports describing techniques for lateral unicompartmental arthroplasty and whether technique influences ROM and function compared to reports for medial unicompartmental arthr...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-011-2005-9

    authors: Berend KR,Kolczun MC 2nd,George JW Jr,Lombardi AV Jr

    更新日期:2012-01-01 00:00:00

  • Intradural recurrence with chondrosarcoma of the spine. A case report and review of the literature.

    abstract::Known for its resistance to chemotherapy and radiation therapy, chondrosarcoma remains largely a surgically managed tumor predisposed to local recurrence and late distant metastasis. A 42-year-old man with known thoracic chondrosarcoma developed progressive low back pain, lower extremity weakness, and urinary incontin...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:

    authors: Vanderhooft JE,Conrad EU,Anderson PA,Richardson ML,Bruckner J

    更新日期:1993-09-01 00:00:00

  • Unilateral posterior lumbar interbody fusion: simplified dowel technique.

    abstract::Two hundred sixteen patients were treated by a simplified unilateral posterior lumbar interbody fusion (U-PLIF) in which the disc was removed and replaced by bone. The disc was approached far laterally by removing two-thirds of the superior facet preserving most of the ligamentum flavum, removing the disc, decorticati...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Blume HG

    更新日期:1985-03-01 00:00:00

  • Treatment of the femoral neck amd trochanteric benign lesions.

    abstract::Thirty-five patients with a benign lesion of the femoral neck or trochanter were treated and seen in followup at the authors' institution from 1988 to 1991. Sixteen men and 19 women between the ages of 18 and 54 years (average, 27 years) were seen at an average followup of 3 years 6 months (range, 2-5 years). Eight pa...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-199607000-00034

    authors: Shih HN,Cheng CY,Chen YJ,Huang TJ,Hsu RW

    更新日期:1996-07-01 00:00:00

  • Do genetic susceptibility, Toll-like receptors, and pathogen-associated molecular patterns modulate the effects of wear?

    abstract:BACKGROUND:Overwhelming evidence supports the concept that wear particles are the primary initiator of aseptic loosening of orthopaedic implants. It is likely, however, that other factors modulate the biologic response to wear particles. This review focuses on three potential other factors: genetic susceptibility, Toll...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1007/s11999-014-3786-4

    authors: Greenfield EM

    更新日期:2014-12-01 00:00:00