An in vivo model to study the anti-malaric capacity of plant extracts.

Abstract:

:An in vivo model to study the antimalaric effect of plant extracts is described. White mice (25-30 g body weight) are treated subcutaneously with 0.6 ml of the diluted extract starting seven days before P. berghei infection; treatment continues until death or for 30 days. Simultaneously 0.2 ml of the extract are applied per os starting three days before infection. In a test of the model, treated and non-treated animals differed in body weight, survival time, haematocrite, parasitemia development, and spleen or liver weight of recent dead or killed mice.

journal_name

Rev Biol Trop

authors

Chinchilla M,Guerrero OM,Abarca G,Barrios M,Castro O

subject

Has Abstract

pub_date

1998-03-01 00:00:00

pages

35-9

issue

1

eissn

0034-7744

issn

2215-2075

journal_volume

46

pub_type

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