Tools in polypharmacy. Current evidence from observational and controlled studies.

Abstract:

:Increasing evidence in managing polypharmacy in the growing elderly population with a higher prevalence of multiple chronic disease is the basis for this paper. Poor adherence, drug-drug interactions, drug-disease interactions, and inappropriate medication challenge the prescriptions of health care providers in this group of patients. Risk factors, the prevalence of polypharmacy, and the impact on health issues will be shown by analyzing the recent literature. Based on intervention trials, several tools in polypharmacy have emerged as practical guides for clinical practice or for the geriatric ward to solve this problem. The Medication Appropriateness Index (MAI) and national lists of potentially inappropriate medication used in clinical practice are presented, including Screening Tool to Alert Doctors to the Right Treatment (START), Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP), and Assess, Comprehensive Geriatric Assessment, Adherence, Development, Emergence, Minimization, Interdisciplinarity, Alertness (ACADEMIA).

journal_name

Z Gerontol Geriatr

authors

Dovjak P

doi

10.1007/s00391-012-0362-y

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

468-72

issue

6

eissn

0948-6704

issn

1435-1269

journal_volume

45

pub_type

杂志文章
  • [Are psychiatric illnesses adequately considered in distribution of nursing care levels according to the nursing care insurance law? Evaluation using a new scale for evaluating need for nursing care by senior citizens].

    abstract::The object of our study is the evaluation of care needs of senior citizens and the adjustment of certain stage of care according to the German Health Care Act ("Pflegeversicherungsgesetz"). For assessment of care needs we developed a new rating scale (BPS). Factor analysis of the rating scale showed 5 dimensions: (1) ...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s003910070023

    authors: Gutzmann H,Metzler P,Schmidt KH

    更新日期:2000-12-01 00:00:00

  • [Regional impact of German statutory pension insurance].

    abstract::The regional impact of old age pension systems has received little attention. For example, the German statutory pension insurance ("gesetzliche Rentenversicherung", GRV) was hitherto to the greatest extent discussed in the context with the situation in West and East Germany. However, the benefits of old age pension sy...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-012-0348-9

    authors: Fachinger U,Stegmann M

    更新日期:2012-07-01 00:00:00

  • [Protein glycation as a pathological mechanism in diabetes].

    abstract::The incidence of diabetes has increased in the recent years. Diabetes is characterized by increased sugar concentrations in the blood. Due to this dysregulation, more carbohydrate-induced modification of proteins - so-called advanced glycation end products (AGEs) - are formed endogenously by non-enzymatic reactions. T...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-011-0282-2

    authors: Simm A,Navarrete-Santos A,Hofmann B,Bushnaq H,Nass N

    更新日期:2012-02-01 00:00:00

  • "N-active": a new comanaged, orthogeriatric ward: observations and prospects.

    abstract::The incidence of hip fractures increases with increasing age. Besides the actual trauma, it is mainly the comorbidities and an increased postoperative complication rate in old patients that lead to increased mortality in this patient population. Around 25% of patients who had previously been living independently conti...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-011-0250-x

    authors: Singler K,Biber R,Wicklein S,Heppner HJ,Sieber CC,Bail HJ

    更新日期:2011-12-01 00:00:00

  • Dementia among older in-hospital patients with obstructive airway disease: frequency and consequences.

    abstract:BACKGROUND:Dementia may influence as a co-morbid condition the management of chronic obstructive airway disease. However, the frequency and the consequences of dementia in older people with chronic obstructive airway disease are largely unknown. PATIENTS AND METHODS:The frequency and the severity of dementia in geriat...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-011-0223-0

    authors: Frohnhofen H,Heuer HC,Willschrei HP,Falkenhahn C

    更新日期:2011-08-01 00:00:00

  • [The future of public health].

    abstract::As the results of the structural reform policy regulating the health care sector, the paper presents the possible path of increasing intrasectoral risk selection and intersectoral risk externalization (especially between the law of health care insurance, the law of statutory nursing insurance, and the German poverty l...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s003910050064

    authors: Schulz-Nieswandt F

    更新日期:1998-12-01 00:00:00

  • [Duodenal ulcers, gastric ulcers and Helicobacter pylori].

    abstract::The mortality in elderly patients over the age of 80 years with peptic ulcers in the case of complications, such as bleeding and perforation is higher than in the general population. Duodenal ulcers are associated with Helicobacter pylori infections in 90% of cases and in 70% of gastric ulcers. The treatment of elderl...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章,评审

    doi:10.1007/s00391-017-1190-x

    authors: Dovjak P

    更新日期:2017-02-01 00:00:00

  • [The German version of the Falls Efficacy Scale-International Version (FES-I)].

    abstract::The German version of the Falls Efficacy Scale-International Version (FES-I), which is presented, was developed for the documentation of fall-related selfefficacy in older persons by a EU-funded expert network (Prevention of Falls Network Europe ProFaNE). The FES-I represents a modification of the original Falls Effic...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-006-0400-8

    authors: Dias N,Kempen GI,Todd CJ,Beyer N,Freiberger E,Piot-Ziegler C,Yardley L,Hauer K

    更新日期:2006-08-01 00:00:00

  • [Support in dying: orientation of expectations and needs of dying patients].

    abstract::Experience and behavior of dying people are on a lot of variables. Age, cultural background, human relations, personality and environment are some of these determinants. For an appropriate care for the dying it is necessary to perceive and realize the expectations and requirements of the dying person. The human relati...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:

    authors: Howe J

    更新日期:1995-07-01 00:00:00

  • [Interventional gerontology in German-speaking countries: a social and behavioral science assessment].

    abstract::This work is aimed at reviewing 20 years of gerontological intervention research within the social and behavioral domain in German speaking countries. Only controlled studies based on adequate measurement instruments are considered. Literature analyses reveal that the issue of cognitive intervention research is well-c...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章,评审

    doi:10.1007/s003910050022

    authors: Wahl HW,Tesch-Römer C

    更新日期:1998-04-01 00:00:00

  • Polypharmacy and older people--the GP perspective.

    abstract::It is well known that problems with compliance rise exponentially when more that 4 drugs are prescribed. The rising use of prescription medicine forces the GP to balance the benefit of evidence group-based appropriate drug use against the problems arising when medication is given to older people and to consider differ...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-005-1104-1

    authors: Vass M,Hendriksen C

    更新日期:2005-09-01 00:00:00

  • [Importance of family for quality of life of the elderly in a social and cultural comparison].

    abstract::This paper explores the role of the family and its contribution to quality of life in old age under a comparative perspective, looking at different European welfare states (Norway, Germany, Spain and Israel). The literature demonstrates a consistent association between well-being and social networks in old age. Interg...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-002-0107-4

    authors: Tesch-Römer C,Motel-Klingebiel A,von Kondratowitz HJ

    更新日期:2002-08-01 00:00:00

  • Development of the Lie-to-Sit-to-Stand-to-Walk Transfer (LSSWT) test for early mobilization in older patients in geriatric rehabilitation.

    abstract:BACKGROUND:Early discharge from a rehabilitation center is only possible, if patients are able to do basic transfers independently (e.g., get up from bed and walk to the toilet). Against this background, the Lie-to-Sit-to-Stand-to-Walk Transfer (LSSWT) test was developed in order to quantify complex transfer abilities ...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-011-0169-2

    authors: Reicherz A,Brach M,Cerny J,Nicolai S,Becker C,Lindemann U

    更新日期:2011-08-01 00:00:00

  • [New oral anticoagulants for prophylaxis of stroke. Results of an expert conference on practical use in geriatric patients].

    abstract::Geriatric patients with non-valvular atrial fibrillation (AF) are increasingly being treated with novel oral anticoagulants (NOAC) to prevent ischemic stroke. This article highlights the outcome of an expert meeting on the practical use of NOAC in elderly patients. An interdisciplinary group of experts discussed the c...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章,评审

    doi:10.1007/s00391-016-1027-z

    authors: Bahrmann P,Harms F,Schambeck CM,Wehling M,Flohr J

    更新日期:2016-04-01 00:00:00

  • [Psychological factors and sleep in the lifeworld nursing home from the nursing home residents' perspective. A qualitative study].

    abstract:BACKGROUND:Sleep disorders are common among nursing home residents. However, the possible involvement of psychological factors has been given little attention up until now. We investigated nursing home residents' perspective on psychological factors and sleep disorders within the nursing home environment. MATERIALS AN...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-013-0534-4

    authors: Herrmann WJ,Flick U

    更新日期:2014-04-01 00:00:00

  • [Trends in participation in nonformal education in the second half of life : Increasing educational participation in retirement].

    abstract:BACKGROUND:Research on nonformal education often focuses on participation within employment. Participation of workers decreases with age; however, recent studies show an increase in participation in nonformal education of older workers. It remains, however, unclear if this trend spills over to retirement. OBJECTIVE:In...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-017-1247-x

    authors: Wiest M,Hoffmann M,Widany S,Kaufmann K

    更新日期:2018-12-01 00:00:00

  • Health-related quality of life of elderly living in the rural community and homes for the elderly in a district of India. Application of the short form 36 (SF-36) health survey questionnaire.

    abstract::The present investigation aimed to assess the health-related QoL (HRQoL) of elderly people living in two settings: (i) rural community and (ii) homes for the elderly in a district of South India. The data are drawn from elderly (>60 years of age) sampled from both settings. The short form 36-item health survey (SF-36)...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-009-0077-x

    authors: Varma GR,Kusuma YS,Babu BV

    更新日期:2010-08-01 00:00:00

  • [The entanglement of ageing and space in cultural educational programs : The spatial structuring of active ageing at the theater and in the Alps].

    abstract:BACKGROUND:Even though the effects of cultural activities on active and positive ageing have been extensively examined, spatial aspects have hardly been considered by research in this field. OBJECTIVES:Instead of understanding active ageing as a result of cultural education, this article focuses on practices of (activ...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章,评审

    doi:10.1007/s00391-020-01751-0

    authors: Gallistl V,Parisot V

    更新日期:2020-08-01 00:00:00

  • [The team of the geriatric day clinic].

    abstract::Composition of staff and therapeutic offers of day-hospitals principally are identical with those of geriatric hospitals. But there are peculiarities in their working: They offer a well balanced combination of somato-, physio-, psycho- and sociotherapy which individually must be planned, perpetually controlled and if ...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:

    authors: Schütz RM

    更新日期:1995-03-01 00:00:00

  • [Age related changes in cellular signal transduction of glucocorticoid hormones in rat brain].

    abstract::Chronic or repeated stress can induce a damage of neurons, especially in hippocampus, by which the degree of damage differs in various species. Sapolski has reported that there is a correlation between hippocampal degeneration, disturbed feedback reaction, and hypersecretion of glucocorticoids. The aim of this study w...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s003910050087

    authors: Martin R,al-Scheibani AH,Martin H

    更新日期:1999-04-01 00:00:00

  • [Assessment of care in patients with dementia in house calls by general practitioners].

    abstract:BACKGROUND:Patients with dementia (PD) are a special challenge for the healthcare system. They are responsible for 5% of the expenditure in the German healthcare service. The disease-related deficits and the associated need for care leads to the fact that patients are not able to live in their own residence and rely on...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-020-01715-4

    authors: Lenz F,Schübel J,Neumann R,Bergmann A,Voigt K

    更新日期:2020-03-18 00:00:00

  • [Delay and cessation of aging processes by manipulation of reproduction, food intake and development in insects].

    abstract::Insects can serve as excellent models to show that the genetically determined life span of organisms as well as that of other traits is characterized by high phenotypic plasticity. Depending on different environmental conditions the life cycle strategy can therefore be highly variable. Thus developmental and aging pro...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章,评审

    doi:10.1007/s00391-004-0231-4

    authors: Collatz KG

    更新日期:2004-06-01 00:00:00

  • [Nonpharmacological treatments: their influence on quality of life of people with dementia and possible impacts by corresponding instruments. A systematic review of literature].

    abstract::Nonpharmacological treatments can improve the quality of life of people with dementia. The objective of this review is to evaluate the effects of nonpharmacological treatments on quality of life and to analyze corresponding instruments by performing a systematic review of the literature. Candidate studies were first i...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00391-012-0341-3

    authors: Weidekamp-Maicher M

    更新日期:2013-02-01 00:00:00

  • [Neuropsychological diagnostics of cognitive deficits : Focus on dementia].

    abstract::Older people often report a decline in their cognitive functions - memory problems and difficulty finding words are frequently mentioned. In this context it is essential to differentiate between age-related cognitive decline and pathological processes as they occur in the context of dementia. Neuropsychological diagno...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-020-01800-8

    authors: Jekel K,Wagner P

    更新日期:2020-12-01 00:00:00

  • [Outcomes of multimorbid vascular surgery patients with and without major amputation in a German geriatric rehabilitation clinic].

    abstract:BACKGROUND:In the course of demographic developments, an increase of vascular surgical procedures including major amputations in very elderly, multimorbid geriatric patients is expected. Due to the high vulnerability of these patients, geriatric rehabilitation directly following the acute inpatient treatment is likely ...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-014-0848-x

    authors: Grund S,Mettlach M,Kieser M,Rath K,Schäfer HG

    更新日期:2018-04-01 00:00:00

  • [The degree of Objective Health Burden (OHB) - an expert assessment of the impairment caused by somatic illnesses in geriatric medicine].

    abstract::The degree of Objective Health Burden (OHB) is an expert assessment of the impairment caused by somatic illnesses. It allows an overall clinical rating of the severity of a patient's somatic condition, considering all available information, not only the content or number of diagnoses. The rating on a five point scale ...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s003910050111

    authors: Schneider G,Nehen HG,Heuft G

    更新日期:1999-08-01 00:00:00

  • [Traffic accidents of senior citizen car drivers].

    abstract::The number of accidents caused by older car drivers increases annually in Germany. Typical errors of older drivers concern the right of way, changes of direction and conflicts with pedestrians at cross walks. These errors are attributed to deficient information gathering and processing caused by old age and illness. I...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s003910050123

    authors: Emsbach M,Friedel B

    更新日期:1999-10-01 00:00:00

  • [Basic functions and specialty standards of support management].

    abstract::Three strategies are followed in handling the key issue within the field of action of care an services for the elderly: securing the material needs of those requiring care, creating appropriate care structures, and providing an effective counselling back-up to alleviate interface problems. Those latter, process-orient...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章,评审

    doi:10.1007/s003910050055

    authors: Wissert M

    更新日期:1998-10-01 00:00:00

  • [European Academy for Medicine of Ageing (EAMA)].

    abstract::The European Academy for Medicine of Ageing was founded in 1995 by a nucleus group of European professors: Duursma (Utrecht, NL), Evans (Oxford, GB), Michel (Geneve, CH) and Stähelin (Basel, CH). The aim was to get an adequate postgraduate training under the auspices of an international faculty. A whole curriculum con...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-005-1113-0

    authors: Nikolaus T

    更新日期:2005-09-01 00:00:00

  • [Trail walking test for assessment of motor cognitive interference in older adults. Development and evaluation of the psychometric properties of the procedure].

    abstract:BACKGROUND:Activities of daily living (ADL), such as walking, often involve the added complexity of walking while doing other activities (i.e. dual task walking). A complex walking task may require a greater motor and mental capacity, resulting in decrements in gait performance not seen for simple walking tasks. AIM:T...

    journal_title:Zeitschrift fur Gerontologie und Geriatrie

    pub_type: 杂志文章

    doi:10.1007/s00391-015-0866-3

    authors: Schott N

    更新日期:2015-12-01 00:00:00