Genetic predisposition to atorvastatin-induced myopathy: a case report.

abstract：WHAT IS KNOWN AND OBJECTIVE:Terlipressin is widely used to treat variceal bleeding and hepatorenal syndrome. We report one case of stubborn hyponatraemia induced by long-term (up to 21 days) therapy with terlipressin and review the side effects of this agent. CASE SUMMARY:A 41-year-old man with variceal rebleeding exp...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Huang Y,Wang M,Wang J

更新日期：2015-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The 4-factor prothrombin complex concentrate (4F-PCC) may be used to emergently achieve haemostasis in patients on anticoagulation prior to surgery. Limited data exist using the intraosseous route of administration of 4F-PCC in patients taking factor Xa inhibitors. CASE DESCRIPTION:We descr...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ratliff P,Nutley K,Schroeder W,Cottingham L

更新日期：2020-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Although the risk of major bleeding with non-vitamin K antagonist oral anticoagulant (NOAC) is low, life-threatening bleeding can occur. CASE SUMMARY:We report a case of an 81-year-old female with deep vein thrombosis who developed bilateral spontaneous haemothorax and haemopericardium afte...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Yu JH,Liu HH,Hsieh MJ,Hsieh IC,Chu PH,Chen DY

更新日期：2020-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Bisphosphonates are the first-line medications for treating osteoporosis. The aim of our prospective study was to compare the efficacy of zoledronate with that of alendronate in women with post-menopausal osteoporosis based on the evaluations of bone mineral density (BMD) and serum levels of...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tan W,Sun J,Zhou L,Li Y,Wu X

更新日期：2016-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Gabapentin has been used for the management of post-herpetic neuralgia (PHN). However, inconsistent results have been reported. This meta-analysis was performed to assess the efficacy and safety of gabapentin 1800 mg/day in PHN patients by conducting a meta-analysis. METHODS:Electronic data...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Fan H,Yu W,Zhang Q,Cao H,Li J,Wang J,Shao Y,Hu X

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Morphine hydrochloride, a major analgesic drug, is being increasingly administered using portable disposable infusion devices. The objective of this study was to investigate the stability of morphine in such a system at two concentrations (2.50 and 5.00 mg/ ml) over a 30-day period. METHOD:Hig...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Oustric-Mendes AC,Huart B,Le Hoang MD,Perrin-Rosset M,Pailler FM,Darbord JC,Prognon P,Gard C,Pradeau D

更新日期：1997-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:In order to improve public health, it is necessary to facilitate patients' easy access to affordable high-quality primary health care, and one enhanced approach to do so may be to provide primary healthcare services in the community pharmacy setting. Discrete choice experiments to evaluate p...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Feehan M,Walsh M,Godin J,Sundwall D,Munger MA

更新日期：2017-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Adherence to evidence-based drug therapy after acute myocardial infarction has increased over the last decades, but is still unsatisfactory. Our objectives are to set out to analyse patterns of evidence-based drug therapy after acute myocardial infarction (AMI), and evaluating socio-demograp...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kirchmayer U,Agabiti N,Belleudi V,Davoli M,Fusco D,Stafoggia M,Arcà M,Barone AP,Perucci CA

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:The role of long-term glycaemic control in minimizing long-term complications of diabetes mellitus is evidence-based and national guidelines recommend a target glycosylated haemoglobin level of approximately 7%. Although the role of self-monitoring blood and urine glucose is less well defined, this activity ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Stewart D,McCaig D,Davie A,Juroszek L,Blackwood L,Findlay N,McCarthy S

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The penetration of generic drugs in the Greek pharmaceutical market is placed among the weakest in the EU. The Greek regulatory framework does not systematically support the development of this subsector and physicians are not provided with incentives for prescribing generics. The aim of this s...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tsiantou V,Zavras D,Kousoulakou H,Geitona M,Kyriopoulos J

更新日期：2009-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Pulmonary sarcomatoid carcinoma (PSC) is characterized by dismal prognosis and resistance to platinum-based chemotherapy. The immune checkpoint inhibitors showed promising efficacy in the treatment of PSC. Camrelizumab is a programmed cell death protein 1 inhibitor; however, current evidence...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kong F,Wang W,Gong L,Wu W,Liu Y

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Although the elimination half-life of most glucocorticoids is short, they are usually administered once daily, or even on alternate days. Our hypothesis was that this practice might compromise the immunosuppressive effect of those drugs during the second part of the administration interval. METHODS:Eight hea...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Uhl A,Czock D,Boehm BO,Zellner D,Mertz A,Keller F

更新日期：2002-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Mebendazole (MBZ) is a broad-spectrum antihelminthic agent of the benzimidazole type. Although MBZ has been reported to cause hepatic injury, case reports of severe hepatic injury are very rare. We report a case of severe hepatitis after administration of MBZ in a patient with Gilbert's synd...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tolomeo M,Colomba C,Meli M,Cascio A

更新日期：2019-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Chronic obstructive pulmonary disease (COPD) is associated with significant morbidity and mortality, and frequent exacerbations are associated with an increased risk of death, deterioration in lung function and reduced quality of life. Current Australian guidelines developed by the Lung Foun...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Brownridge DJ,Zaidi STR

更新日期：2017-06-01 00:00:00

abstract：:A population pharmacokinetic study was conducted on a total of 70 patients receiving gentamicin therapy. The patients included those with normal renal function and those with varying degrees of renal impairment. The parameters studied were the apparent volume of distribution and the plasma clearance of gentamicin. The...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Lanao JM,Berrocal A,Calvo MV,Perez M,de la Calle B,Domínguez-Gil A

更新日期：1989-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Chemotherapy can increase treatment-related mortality associated with future haematopoietic stem cell transplantation (HSCT) for patients with relapsed/refractory acute myeloid leukaemia (AML). There is usually insufficient time to find a suitable unrelated donor for these patients. We repor...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhang C,Chen XH,Liu J,Gao L,Liu Y,Gao L,Kong PY,Zhang X

更新日期：2015-06-01 00:00:00

abstract：:The effects of age and co-medication on steady-state phenobarbital (PB) level-dose (L/D) ratios were evaluated retrospectively in 539 paediatric patients. The PB L/D ratio increased significantly with age up to 15 years. Associated anti-epileptic therapy affected the PB L/D ratio, which was significantly increased in ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Yukawa E,Higuchi S,Aoyama T

更新日期：1992-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The use of prophylactic antibiotics in clean operations was routine in China before 2011. Along with the appeal for using antibiotics rationally by WHO in 2011, China launched a national special rectification scheme on clinical use of antibiotics from April that year. The scheme, aimed at ac...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhou Y,Ma LY,Zhao X,Tian SH,Sun LY,Cui YM

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The uptake of new medicines is slower in the UK than in many other countries. Previous research found that cost and price have little influence on general practitioner (GP) behaviour, but recent UK government policy may have heightened cost-consciousness. Focussing on new medicines, this review...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mason A

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Epilepsy is a disease requiring chronic therapy with antiepileptic drugs (AEDs). Many conventional AEDs currently available have either too rapid an absorption or elimination, requiring the patient to take multiple doses per day, which may adversely impact adherence or cause peak-related side-effects. Conseq...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Reed RC,Meinhold J,Dutta S,Liu W,Qiu Y

更新日期：2010-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:With increased opioid use, drug-drug interactions (DDIs) and associated adverse events are growing among geriatric patients. However, the clinical significance of potential metabolic DDIs associated with opioid use has not been fully evaluated among geriatric patients. Particularly, cytochro...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kim JH,Kim JY,Lee N,Yee J,Gwak HS

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Patients with congestive heart failure (CHF) are at risk for hyperkalemia because of coexisting comorbidities and use of multiple medications that impair potassium (K) excretion such as angiotensin converting enzyme (ACE) inhibitors. OBJECTIVE:To identify clinical factors associated with hyperkalemia on ini...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ramadan FH,Masoodi N,El-Solh AA

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To determine whether patients who are prescribed a highly active antiretroviral therapy regimen, that minimizes medical and lifestyle contraindications, will be better able to adhere to their drug regimens and will have better clinical outcomes, than patients who do not have such a regimen. METHODS:A retrosp...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Lal LS,Grimes RM,Swint JM,Risser J

更新日期：2006-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Lowering haemoglobin A(₁c) (HbA(₁c)) has clearly been shown to reduce microvascular complications of diabetes and possibly macrovascular disease and vitamin E has been suggested as a possibly useful intervention. Our aim is to evaluate the effect of vitamin E supplementation on glycaemic con...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Suksomboon N,Poolsup N,Sinprasert S

更新日期：2011-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Pregabalin is used for neuropathic and postherpetic pain and generalized anxiety. The aim of this study was to obtain the onset profiles of adverse events (AE) related to falls (AEFs) such as "somnolence," "dizziness," "loss of consciousness" and "fall" onset and several clinical factor comb...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mukai R,Hasegawa S,Umetsu R,Nakao S,Shimada K,Uranishi H,Masuta M,Suzuki H,Nishibata Y,Nakamura M

更新日期：2019-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Amlodipine overdose is common; however, the dose and timing of intravenous lipid emulsion (ILE) therapy as a management strategy remain debatable. CASE DESCRIPTION:A 73-year-old man received a single bolus (1.5 mL/kg) of ILE therapy following massive ingestion of multiple drugs, including a...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ando M,Nakasako S,Ariyoshi K,Yamaguchi M,Sakizono K,Minowa K,Fukushima S,Sugioka N,Hashida T

更新日期：2019-12-01 00:00:00

abstract：:Pharmacokinetic interactions between antiepileptics represent a major potential complication of epilepsy treatment because drug combinations are common. This review discusses pharmacokinetic drug interactions of clinical significance involving antiepileptics and cytochrome P450 (CYP). Most commonly used antiepileptics...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tanaka E

更新日期：1999-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Lemierre's syndrome is often misdiagnosed as a common cold or viral infection. Fusobacterium necrophorum is the most common causative organism. The recommended treatment regimen is 6 weeks of a beta-lactam antibiotic along with metronidazole. CASE DESCRIPTION:We present two cases of Lemierr...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Le C,Gennaro D,Marshall D,Alaev O,Bryan A,Gelfman A,Wang Z

更新日期：2019-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Far more patients are now surviving cancer than ever before because of major advances in the diagnosis and treatment of primary and metastatic malignancy. Adjuvant chemotherapeutic drug and combination regimens have contributed to the success. However, persistent residual adverse effects inv...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Raffa RB

更新日期：2011-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Moringa oleifera (MO) Lam (Moringaceae) is commonly used as food supplement and as medicine in most African countries where malaria is also endemic. Therefore, co-administration of MO with antimalarials is a possibility. This study investigated the effects of MO leaves powder on the pharmaco...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Olawoye OS,Adeagbo BA,Bolaji OO

更新日期：2018-10-01 00:00:00