Temporal trends in Bordetella pertussis populations, Denmark, 1949-2010.

Abstract:

:We used multilocus variable-number tandem repeat analysis and multiple antigen sequence typing to characterize isolates of Bordetella pertussis strains circulating in Denmark during periods with and without pertussis vaccination coverage. Our results show substantial shifts in the B. pertussis population over time and a reduction in genetic diversity. These changes might have resulted from the introduction of pertussis vaccines in Denmark and other parts of Europe. The predominant strains currently circulating in Denmark resemble those in other European countries.

journal_name

Emerg Infect Dis

authors

Petersen RF,Dalby T,Dragsted DM,Mooi F,Lambertsen L

doi

10.3201/eid1805.110812

subject

Has Abstract

pub_date

2012-05-01 00:00:00

pages

767-74

issue

5

eissn

1080-6040

issn

1080-6059

journal_volume

18

pub_type

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