Abstract:
:The study has demonstrated that anticancer drug 5-fluorouracil causes acute toxicity and interferes with the growth of green microalgae, Scenedesmus vacuolatus. It accumulates in microalgae biomass with bioaccumulation factor of 1.84 × 10(4) and further integrates into the DNA and RNA of microalgae. In addition, the labelled microalgae genome is transferred into protozoan Tetrahymena pyriformis on feeding and is retained in the food vacuoles of predator organisms. This biotransfer of labelled 5-fluorouracil via genomic material was evaluated using radioactivity in Tetrahymena cell pellets though radioactivity did not detect anticancer drug in the genome of the predator organism.
journal_name
Bull Environ Contam Toxicoljournal_title
Bulletin of environmental contamination and toxicologyauthors
Ud-Daula A,Pfister G,Schramm KWdoi
10.1007/s00128-012-0536-8subject
Has Abstractpub_date
2012-04-01 00:00:00pages
548-54issue
4eissn
0007-4861issn
1432-0800journal_volume
88pub_type
杂志文章abstract::To clarify whether Oryzias congeners, including freshwater, brackish water, and marine medaka, would be useful models for evaluating environmental chemical effects in various aquatic ecosystems, we examined the influence of salinity on their embryo development. We also compared the toxicity values of the organotin com...
journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
pub_type: 杂志文章
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更新日期:1975-11-01 00:00:00
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journal_title:Bulletin of environmental contamination and toxicology
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journal_title:Bulletin of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00128-019-02690-2
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journal_title:Bulletin of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00128-017-2148-9
更新日期:2017-09-01 00:00:00