Absence of nocturnal fall in blood pressure in elderly persons with Alzheimer-type dementia.

Abstract:

:Circadian changes of the blood pressure and heart rate in elderly normotensive bedridden patients with severe dementia of the Alzheimer type (group D) were compared with those in elderly normotensive bedridden patients without dementia (group R), normotensive subjects with normal daily activity (group N), and hypertensive patients with normal daily activity (group H). In groups R, N, and H, the blood pressure increased in the afternoon and decreased at midnight; in group D, however, although it increased in the afternoon, it did not decrease at night. The circadian changes of the heart rate were similar in all four groups, showing maxima in the afternoon and minima at midnight. Thus, a specific alteration was found in the circadian rhythm of the blood pressure in patients with Alzheimer-type dementia.

journal_name

J Am Geriatr Soc

authors

Otsuka A,Mikami H,Katahira K,Nakamoto Y,Minamitani K,Imaoka M,Nishide M,Ogihara T

doi

10.1111/j.1532-5415.1990.tb04418.x

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

973-8

issue

9

eissn

0002-8614

issn

1532-5415

journal_volume

38

pub_type

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