Abstract：
:Melnick-Needles Syndrome (MNS) is a congenital syndrome associated with severe architectural disorder of the skeletal system that can cause significant effects on the craniofacial skeleton including poor aesthetics, impaired speech and masticatory problems. The authors report a case of a female patient who experienced masticatory constraint, hindered speech and functional problems related to a severe bite dysfunction due to the mandibular hypoplasia and the underlying bony architectural disorder associated with MNS. The patient underwent bilateral sagittal split osteotomy (BSSO) to correct her skeletal malocclusion and improve the characteristic aesthetics and speech. The inherent bony abnormalities with their altered collagen structure presented unique challenges to orthognathic surgery in this patient with an unpredictable bone healing process. In MNS patients a fragile trabecular bone structure and an increased bleeding tendency is thought to delay or forestall wound healing. The patient was treated successfully with BSSO and monocortical plate fixation following a well-established algorithm from orthodontic preparation to surgical protocol. A very satisfying outcome has been achieved, concerning functional rehabilitation and aesthetic improvement. A review of the literature revealed that little is known about bone regeneration and fracture healing in cases with MNS.
journal_name
Int J Oral Maxillofac Surgjournal_title
International journal of oral and maxillofacial surgeryauthors
Jung S,Wermker K,Joos U,Kleinheinz Jdoi
10.1016/j.ijom.2011.08.007subject
Has Abstractpub_date
2012-03-01 00:00:00pages
309-12issue
3eissn
0901-5027issn
1399-0020pii
S0901-5027(11)01407-Xjournal_volume
41pub_type
杂志文章,评审abstract：:Histopathology is the gold standard in the diagnosis of cancer and dysplasia. Screening for the disease in high-risk populations(6,15) and choosing the correct site for biopsy have implications for the choice of follow-up intervals and therapy. Sully & Field(12) suggest that molecular genetic analysis, such as the pol...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：
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abstract：:A case of diffuse, large-cell non-Hodgkin's lymphoma presenting as pericoronitis in the oral cavity is described. The diagnostic pitfalls are briefly discussed. ...
journal_title：International journal of oral and maxillofacial surgery
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doi：10.1016/s0901-5027(05)80741-6
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abstract：:The aim of this study was to evaluate the effects of combining a porous poly(L-lactide-co-epsilon-caprolactone)/beta-tricalcium phosphate membrane and gelatin sponge incorporating basic fibroblastic growth factor (bFGF) on bone regeneration in mandibular ridges. Four full-thickness saddle-type defects (10 mm long x 5 ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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abstract：:72 cases of ameloblastoma were obtained from the files of the Department of Pathology, School of Dentistry, Aichi-Gakuin University for the years January 1970 through December 1983. The cases were analyzed with respect to sex, age, duration, site histopathology, and treatment. Of 72 patients, 63 had no previous therap...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
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journal_title：International journal of oral and maxillofacial surgery
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doi：10.1016/j.ijom.2006.06.014
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2006.10.002
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2004.03.014
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1054/ijom.2000.0023
更新日期：2001-04-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2009.10.024
更新日期：2010-03-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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更新日期：2015-08-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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更新日期：2015-07-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2009.04.009
更新日期：2009-08-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2008.07.008
更新日期：2008-12-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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更新日期：2017-12-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2013.10.017
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80666-6
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80180-8
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
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更新日期：2016-05-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
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journal_title：International journal of oral and maxillofacial surgery
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更新日期：2004-09-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 临床试验,杂志文章
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更新日期：1993-08-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
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journal_title：International journal of oral and maxillofacial surgery
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1992-06-01 00:00:00
