Abstract:
:Prognosis for parotid carcinomas is not-well defined. The authors have developed models that could be useful to define subgroups of patients with differential risks. Clinical and pathological variables, and immunohistochemically studied MMP-7, MMP-9, MT1-MMP, and VEGF proteins were analysed in 42 patients with parotid gland cancer, regarding disease-specific survival and loco-regional recurrence. A prognostic index (PI) was calculated by combining age, disease stage, squamous cell carcinoma histology, and vascular endothelial growth factor immunoexpression. Based on the values of this PI, patients were classified into three groups: 1.89-4.18 (SPI1); 4.2-7 (SPI2), and >7 (SPI3). Corresponding 5-year survival rates for these groups of patients were of 89%, 47%, and 21%, respectively. Regarding loco-regional recurrence three different patient groups were calculated combining three factors: T, N and grade. Differences amongst them were statistically significant and the estimated hazard ratios were 6.4 and 24.2 for intermediate and poor prognosis, respectively, taking the good prognostic group as reference. The authors identified several significant prognostic factors and they propose two PIs for disease-specific survival and for loco-regional recurrence. They allow for the calculation of death risk and recurrence for a given patient, providing a practical system for clinical use.
journal_name
Int J Oral Maxillofac Surgjournal_title
International journal of oral and maxillofacial surgeryauthors
Lequerica-Fernández P,Peña I,Villalaín L,Rosado P,de Vicente JCdoi
10.1016/j.ijom.2011.04.008subject
Has Abstractpub_date
2011-08-01 00:00:00pages
821-8issue
8eissn
0901-5027issn
1399-0020pii
S0901-5027(11)00185-8journal_volume
40pub_type
杂志文章abstract::The aim of this study was to evaluate the clinical efficacy of 4% articaine (Ar4) compared to 2% mepivacaine (Me2), both in combination with 1:100,000 epinephrine, in a unique soft tissue model. This was a randomized, double-blind, crossover clinical trial. The anaesthetic was applied to the lower lip using a computer...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijom.2017.11.011
更新日期:2018-07-01 00:00:00
abstract::The aim of this study was to measure changes in buccal alveolar crestal bone levels after immediate placement and loading of dental implants with Morse taper prosthetic abutments after tooth extraction. This study followed the STROBE guidelines regarding prospective cohort studies. The sample comprised 12 patients wit...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2014.11.009
更新日期:2015-03-01 00:00:00
abstract::Osteochondromas (OC) in the craniofacial region are very rare. Following on from a literature review published in 2011, further single case reports and case series are reviewed herein. To date, approximately 235 studies on OC of the mandibular condyle have been published in the English language literature. There is de...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,评审
doi:10.1016/j.ijom.2016.04.005
更新日期:2016-09-01 00:00:00
abstract::Eagle syndrome, or calcification of the stylohyoid ligament, is a rare condition that may present a clinical diagnostic dilemma for those unfamiliar with its existence and its typical presenting signs and symptoms. Management of this disease process may involve either non-surgical or surgical treatment options. When s...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2015.03.021
更新日期:2015-09-01 00:00:00
abstract::Although cartilaginous exostosis is considered to be the most common tumor of the skeleton, it is relatively uncommon in the jaws. The pathogenesis of the lesion is unclear. Three cases are presented and the development of the tumors from embryonic cartilage is discussed. ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/s0901-5027(06)80034-2
更新日期:1996-10-01 00:00:00
abstract::The aim of this study was to measure bone levels around zirconia implants during follow-up of up to 3 years. Additionally, the effect of clinical contact point positions on the papilla deficit was evaluated. Eighty-one patients with 105 zirconia implants were examined at the 3-year follow-up. Bone levels were measured...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2017.10.013
更新日期:2018-04-01 00:00:00
abstract::This study was performed to test a protocol for trans-implant treatment of chronic recurrent maxillary sinusitis (CRS), via implants with an internal removable sealing screw. The appropriate indications for treatment, optimal number of treatment sessions, and general schedule of treatment and follow-up were assessed. ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2020.01.025
更新日期:2020-07-01 00:00:00
abstract::A clinically successful technique for temporomandibular joint (TMJ) arthroscopy by the inferolateral approach is reported. The outline of the superior and inferior articular cavities of the TMJ except for the lower anterior pouch could be visualised; arthroscopy could be performed on most patients under local anesthes...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/s0300-9785(86)80029-1
更新日期:1986-08-01 00:00:00
abstract::Titanium osteosynthesis is currently the fixation system of choice in maxillofacial traumatology. Biodegradable osteosynthesis systems have the ability to degrade in the human body. The aim of this study was to conduct a systematic review, with meta- and trial sequential analyses, to assess the efficacy and morbidity ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,meta分析
doi:10.1016/j.ijom.2019.11.009
更新日期:2020-07-01 00:00:00
abstract::There is increasing evidence that dietary folic acid deficiency in utero may increase the risk of developing the 'cleft lip with or without cleft palate' (CL±P) variant of orofacial cleft. Coeliac disease is a common cause of folic acid malabsorption, and in the majority of cases remains undiagnosed. This pilot study ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2013.03.021
更新日期:2013-11-01 00:00:00
abstract::A case of metastatic osteosarcoma in the submental vestibule of the oral cavity and the lung is described in an 18-year-old male with primary osteosarcoma occurring in the sacrum. Dissemination of osteosarcoma to other organs, especially early to the lung, is common, but its metastasis to the oral mucosa has been rare...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2006.04.004
更新日期:2006-11-01 00:00:00
abstract::The purpose of this study was to evaluate the outcomes of surgery involving the use of folded trapezius flaps to repair large pharyngocutaneous fistulae (PCFs) developing after salvage total laryngectomy. Folded extended vertical lower trapezius island myocutaneous flaps (TIMFs) were created to repair large PCFs that ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2018.05.019
更新日期:2018-10-01 00:00:00
abstract::The relationship between temporomandibular joint (TMJ) pain and the magnetic resonance imaging (MRI) finding of articular disc displacement is debated. The purpose of this study is to investigate the correlation between TMJ pain and anterior disc displacement (ADD) using pseudo-dynamic MRI. A retrospective review of M...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2012.05.023
更新日期:2012-12-01 00:00:00
abstract::The aim of this systematic review was to answer the question: What are the treatments available for bisphosphonate-related osteonecrosis of the jaws (BRONJ) and their outcomes? A literature search of PubMed, Cochrane Library, and Web of Science databases was conducted in accordance with the PRISMA statement, search ph...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,评审
doi:10.1016/j.ijom.2015.01.026
更新日期:2015-05-01 00:00:00
abstract::A haemophilic pseudotumour is basically an encapsulated haematoma. It is an infrequent complication, estimated to affect 1-2% of severe haemophiliacs, although it has also been reported in patients with mild and moderate haemophilia. A history of trauma is reported in most cases, and the onset of symptoms varies from ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2006.10.002
更新日期:2007-06-01 00:00:00
abstract::The purpose of this meta-analysis was to compare implant survival, marginal bone loss, and complications between immediate and conventional loading of single implants installed in the posterior mandible. An extensive electronic search was performed of PubMed, Web of Science, and the Cochrane Central Register of Contro...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ijom.2015.07.014
更新日期:2016-01-01 00:00:00
abstract::This literature review assessed the risk factors linked to inferior dental nerve (IDN) and lingual nerve (LN) deficits following lower wisdom tooth surgery. A computer search of several databases with specified key words was performed. 32 articles were selected; the risk factors for IDN deficit were reported in 4 arti...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,评审
doi:10.1016/j.ijom.2010.09.005
更新日期:2011-01-01 00:00:00
abstract::The transverse inclination, height and width of 20 lingually placed hydroxylapatite (HA) implants, to augment the atrophic mandibular ridge, were examined using computed tomography of cross sections through the first molar region. Favourable prosthetic conditions are achieved if the HA-implants are placed in a lingual...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/s0901-5027(05)80154-7
更新日期:1991-10-01 00:00:00
abstract::Gastrointestinal stromal tumours are characteristically positive for KIT (reflective of the c-KIT gene). A case is reported of an apparent rapidly growing gastrointestinal stromal tumour, which arose in the floor of the mouth and metastasized to the left neck without evidence of disease elsewhere. ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2007.01.015
更新日期:2007-07-01 00:00:00
abstract::Octacalcium phosphate (OCP) and porcine atelocollagen sponge composites (OCP/Col) markedly enhanced bone regeneration in a rat cranial defect model. To assess clinical application, the authors examined whether OCP/Col would enhance bone regeneration in an alveolar cleft model in an adult dog, which was assumed to refl...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2010.07.015
更新日期:2010-12-01 00:00:00
abstract::This study was performed to investigate sinus floor augmentation with two different particle sizes of demineralized bovine bone mineral (DBBM) by means of histological and immunohistochemical (IHC) analysis. A randomized clinical trial was conducted involving 10 individuals requiring two-stage bilateral maxillary sinu...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijom.2018.09.003
更新日期:2019-06-01 00:00:00
abstract::This investigation was undertaken to correlate the scintigraphic and histological features of condylar hyperplasia to identify consistent diagnostic findings. A series of 34 surgically excised condyles were examined from a 5 year period. Of these, 20 were diagnosed clinically and histologically as condylar hyperplasia...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/s0901-5027(05)80196-1
更新日期:1990-04-01 00:00:00
abstract::Analysis of peri-implant crevicular fluid (PICF) offers a non-invasive means of studying the host response in peri-implant disease and may provide an early indication of patients at risk for active disease. This study examined the PICF levels of interleukin-1beta (IL-1beta), tumour necrosis factor alpha (TNF-alpha), i...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2010.01.014
更新日期:2010-05-01 00:00:00
abstract::A case of peripheral calcifying odontogenic cyst is presented. The nature of the lesion as a neoplasm is discussed including review of the literature. The terminology proposed for this lesion is "dentinogenic ghost cell tumor." ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/s0901-5027(87)80117-0
更新日期:1987-10-01 00:00:00
abstract::A case of incomplete midline cervical cleft of the upper neck is reported. It showed histological resemblance to a mature teratoma with three different germ-cell components, including cartilage, striated muscles, small salivary glands, and nerves. ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/s0901-5027(05)80731-3
更新日期:1992-10-01 00:00:00
abstract::The purpose of this study was to analyse the causes of venous compromise and flap failure in radial forearm free flap (RFFF) surgery for intraoral reconstruction. One hundred seventy-eight RFFF reconstructions were reviewed retrospectively for intraoral defects. Of the 13 flaps with venous obstruction, 9 flaps were sa...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2012.01.016
更新日期:2012-04-01 00:00:00
abstract::A systematic review of English and non-English articles on the complications of mandibular distraction osteogenesis (MDO) for patients with developmental deformities was performed, in accordance with the PRISMA statement. Search terms expressing distraction osteogenesis were used in 'AND' combination with search terms...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,评审
doi:10.1016/j.ijom.2014.09.007
更新日期:2015-01-01 00:00:00
abstract::Thirty cases of osteosarcoma of the jaws were reviewed (20 men and 10 women, mean age 34 years). Seventeen lesions occurred in the mandible and 13 in the maxilla. Swelling without pain was the most common presenting symptom. Thirteen lesions were initially misdiagnosed as odontogenic infections. Numbness as a presenti...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,评审
doi:10.1016/s0901-5027(97)80819-3
更新日期:1997-06-01 00:00:00
abstract::Chondrosarcomas are the malignant cartilagenous tumors and they are seen rarely in the head and neck area. They are usually slow growing lesions. The head and neck chondrosarcomas may show an aggressive course and the occurrence of this malignant cartilagenous tumor in the parapharyngeal space is only a few. They are ...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2005.01.006
更新日期:2005-10-01 00:00:00
abstract::An example of a central odontogenic fibroma is presented. This is a rare, benign neoplasm which affected the molar region of the left side of the mandible of a 63-year-old female Caucasian. Histologically, it consisted of fibroblast-like cells lying in a rather myxomatous delicate collagenous stroma. Few islands of od...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/s0901-5027(88)80156-5
更新日期:1988-04-01 00:00:00