Abstract：
:Ochratoxin A is one of the most abundant food- contaminating mycotoxins in the world that is immunosuppressive, genotoxic, teratogenic and carcinogenic. Malondialdehyde is a naturally occurring product of lipid peroxidation that is mutagenic and carcinogenic. 8-Hydroxydeoxyguanosine is produced during the interaction of reactive oxygen species and DNA. In this study, Ochratoxin A, malondialdehyde and 8-Hydroxydeoxyguanosine levels of individuals in the study group were measured and results were correlated with each other. Additionally, the correlation of biomarker levels to smoking habit, alcohol and coffee consumption, age and gender of individuals was investigated. As a result of these assessments, a significant correlation was observed between Ochratoxin A exposures and malondialdehyde and 8-Hydroxydeoxyguanosine levels.
journal_name
Bull Environ Contam Toxicoljournal_title
Bulletin of environmental contamination and toxicologyauthors
Ates I,Ulker OC,Akdemir C,Karakaya Adoi
10.1007/s00128-011-0225-zsubject
Has Abstractpub_date
2011-03-01 00:00:00pages
258-62issue
3eissn
0007-4861issn
1432-0800journal_volume
86pub_type
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