Abstract:
BACKGROUND:Antipsychotics are commonly used in the elderly despite limited efficacy and safety data from randomised controlled trials. Observational comparative safety studies of antipsychotics vary, which may be due to confounding. OBJECTIVE:To compare the characteristics of typical and atypical antipsychotic initiators. METHODS:Using the Australian Government Department of Veterans' Affairs claims dataset, we compared patient and prescribing physician characteristics and health care utilisation between atypical and typical antipsychotic initiators. Significant independent predictors of use were calculated using a multivariate log-binomial model. RESULTS:Compared to patients initiated on typical antipsychotics (n=10,966), patients initiated on atypical antipsychotics (n=9,239) were less likely to be male (Relative Risk (RR)=0.91, 95% CI 0.89-0.94) and have prior dispensing of morphine (RR=0.53, 95% CI 0.49-0.57) and oral corticosteroids (RR=0.86, 95% CI 0.81-0.91) and to have been hospitalised for myocardial infarction or pneumonia. Patients initiated on atypical antipsychotics were more likely to be in aged care (RR=1.08, 95% CI 1.05-1.12), to be prescribed the medicine by their usual doctor (RR=1.12, 95% CI 1.09-1.16) and have prior dispensing of anticholinesterases (RR=1.19, 95% CI 1.15-1.23), antidepressants (RR=1.18 95% CI 1.15-1.22) and anti-parkinson medications (RR=1.30, 95% CI 1.25-1.36). CONCLUSIONS:Differences between typical and atypical antipsychotic initiators indicate the potential for confounding in observational studies. Future pharmacoepidemiogical research in Australia, investigating the adverse events of antipsychotics, should consider the variables identified in this study to control for confounding.
journal_name
Aust N Z J Public Healthjournal_title
Australian and New Zealand journal of public healthauthors
Pratt N,Roughead E,Salter A,Ryan Pdoi
10.1111/j.1753-6405.2010.00613.xsubject
Has Abstractpub_date
2010-12-01 00:00:00pages
589-93issue
6eissn
1326-0200issn
1753-6405journal_volume
34pub_type
杂志文章abstract:BACKGROUND:Information on the treatment of women with breast cancer in Australia is generally available only from special surveys. Analysis of routinely collected datasets may be more timely and cost effective, if the data are sufficiently accurate and complete. OBJECTIVE:To evaluate the accuracy and completeness of d...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.1998.tb01490.x
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVES:To investigate an abattoir outbreak of Q fever in southem New South Wales with reference to the protective effect and safety of the formalin-inactivated Q fever vaccine (Q Vax) administered before and during the outbreak. METHODS:In September 1998, after notification of four Q fever cases in the abattoir, a...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.2001.tb00595.x
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVE:Examine the feasibility and acceptability of an electrocardiogram (ECG) attached to a mobile phone (iECG) screening device for atrial fibrillation (AF) in Aboriginal Controlled Community Health Services (ACCHS) and other community settings. METHODS:Semi-structured interviews were conducted with ACCHS staff i...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/1753-6405.12905
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVES:To conduct a critical and systematic analysis of descriptive studies regarding the health, development and wellbeing status of Indigenous children in Australia and to map them according to 1) Reported Indigenous involvement in the research process; 2) Domains of the life-course model of health; and 3) Geogra...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章,评审
doi:10.1111/j.1753-6405.2009.00339.x
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:To elicit community preferences for colorectal cancer (CRC) screening by faecal occult blood test (FOBT) using discrete choice modeling (DCM). To provide policymakers with information that would assist them in designing the future national screening program. METHODS:301 participants in central Sydney, aged ...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.2003.tb00425.x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of established risk factors for ischaemic heart disease (IHD) in New Zealand adults and compare the prevalence in adults with and without this disease. DESIGN:Data were obtained from the 2002/03 New Zealand Health Survey. Risk factor prevalence was determined by: self-reported doct...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.2005.tb00218.x
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVES:To determine the acceptability of intervention strategies that increase the responsible service of alcohol by non-metropolitan rugby league clubs. METHOD:Rugby league clubs were provided an information kit and advice by local public health workers, police and a lead agency regarding their responsible servic...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.2000.tb01574.x
更新日期:2000-06-01 00:00:00
abstract::The prevalence of human immunodeficiency virus (HIV) in male prisoners in South Australia from July 1989 to June 1994 was ascertained from a repeated cross-sectional study. We also compared the criminological and demographic characteristics and histories of drug use of 39 HIV-infected prisoners and a randomly selected...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.1997.tb01757.x
更新日期:1997-10-01 00:00:00
abstract::Schools represent a very attractive setting for health promotion. Most children and young people attend school, professional educators are in place, and most school communities are microcosms of the larger community, providing opportunities for children to develop and practice the skills necessary to support a healthy...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.1997.tb01716.x
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:To describe and compare vaccination coverage for Aboriginal and Torres Strait Islander (hereafter referred to as Indigenous) adults in 2004-05 and 2012-13, including the impact of national vaccination funding initiatives. METHODS:National Aboriginal and Torres Strait Islander Health cross-sectional surveys ...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/1753-6405.12944
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:The primary aim of the study was to investigate the determinants of attitudes towards alternative medicine. The study also examined the dimensionality of dissatisfaction with conventional medicine. METHOD:The data was based on a telephone survey of a random sample of 787 Victorians. The survey was conducted...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.1999.tb01254.x
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:To illustrate how regional variation in data quality could explain some or all of the apparent regional differences in the health status of Indigenous Australians. METHODS:A series of simple hypothetical numerical examples is provided, with varying assumptions regarding the accuracy of identification of Indi...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.2002.tb00355.x
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:Investigator-driven research and the use of peer review are contentious in community-based research and are particularly problematic in Indigenous research. In this project, we conducted a qualitative study among stakeholders in an Australian Aboriginal majority-controlled research-funding organisation to exa...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1753-6405.2007.00090.x
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:When the World Health Organization Quality of Life tools were developed by 15 collaborating centres in 14 countries, respondents rated how important they considered various facets of health-related quality of life. The present study compared quality of life importance ratings from New Zealanders with the glob...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/1753-6405.12350
更新日期:2015-08-01 00:00:00
abstract::The eye health of rural Aboriginal Australians is known to be poor. Over the past 20 years, Aboriginal communities in remote parts of Australia have had increasing access to eye health services through the National Trachoma and Eye Health Program (NTEHP). Using published and unpublished data, we examined trends in the...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.1996.tb01049.x
更新日期:1996-08-01 00:00:00
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journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/1753-6405.12425
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:To estimate the impact of integrating the price of greenhouse gas emissions into the price of food commodities on dietary and weight-related risk factors and associated disease burden in Australia, as well as on national emissions reductions and public revenues. METHODS:We used country-specific data for Aust...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/1753-6405.12830
更新日期:2018-12-01 00:00:00
abstract::There is widespread inappropriate use of pharmaceuticals. Problems are with the prescribing and dispensing as well as with the taking of medicines. Levels of potentially inappropriate prescribing were estimated in the population of Australian veterans and war widows. This group tends to have multiple medical condition...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.1997.tb01737.x
更新日期:1997-08-01 00:00:00
abstract::This paper describes initial partnership development in PRISM (Program of Resources, Information and Support for Mothers), a community-randomised trial to improve maternal health in the first year after birth conducted in Victoria in the period 1998--2003. First, we discuss the principles underpinning community recrui...
journal_title:Australian and New Zealand journal of public health
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1467-842x.2004.tb00030.x
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:To review available literature addressing the issue of whether smoking status of Indigenous Health Workers (IHWs) impedes provision of health information about smoking tobacco to their communities. METHOD:Databases were searched for publications that examined IHWs' smoking status or quit support programs for...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章,评审
doi:10.1111/j.1753-6405.2010.00632.x
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To determine the accuracy of the hospital discharge coding of heart failure (HF) in the Western Australian (WA) Hospital Morbidity Data (HMD). METHODS:A retrospective medical chart review of a sample of 1,006 patients with a principal diagnosis code indicating HF in the WA HMD was undertaken. Validation was ...
journal_title:Australian and New Zealand journal of public health
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doi:10.1111/j.1753-6405.2008.00269.x
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:In 1991, an intervention trial of the efficacy of an asthma self-management plan was carried out in partnership with a rural Mäori community. The program relied on Mäori community health workers and other health professionals working in partnership, was delivered through clinics in traditional Mäori communit...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.1999.tb01544.x
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVES:To assess current approaches to inclusion of equity in economic analysis of public health interventions and to recommend best approaches and future directions. METHODS:We conducted a systematic review of studies that have used socioeconomic position (SEP) in cost-effectiveness analyses. Studies were identif...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章,评审
doi:10.1111/1753-6405.12709
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To examine the impact of the Canterbury earthquakes on the important adolescent transition period of school leaving. METHOD:Local and national data on school leaving age, attainment of National Certificate of Educational Achievement (NCEA) standards, and school rolls (total registered students for schools) w...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/1753-6405.12625
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:Estimate the prevalence of sexual behaviour and alcohol use and examine the association between excessive alcohol use and risky sexual behaviour in late secondary students in Victoria, Australia. METHOD:The sample of Year 11 students from government and independent schools participating in the 2008 Internati...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/1753-6405.12014
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To apply a 'health gain' approach to population-based cancer control. METHOD:We calculated the potential years of life otherwise lost prematurely which could be 'regained' through implementation of cancer control programs for which Level I or Level II evidence already exists for population outcomes. RESULTS...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.1999.tb01314.x
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of influenza immunisation of residents within South Australian aged care homes, reasons why vaccination is not given, the policy associated with vaccination administration and the source of the vaccination. METHOD:A clustered, multistage, area sample was used to assess the provisi...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1467-842x.2005.tb00746.x
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:To determine whether capture-recapture analysis provides more reliable estimates of the cumulative incidence and prevalence of leg ulcers in Auckland, New Zealand. METHODS:A population-based, cross-sectional study was conducted in the Central and North Auckland health districts of New Zealand in 1998. Cases ...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1467-842x.2002.tb00346.x
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:To determine the reservoir and risk factors of HCV infection in a hospital population. METHODS:The presence of anti-HCV in 2,119 endoscopy patients was related to putative risk factors for exposure using the SAS statistical package. RESULTS:Most of the 4.7% of anti-HCV positive patients had multiple risk fa...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/j.1753-6405.2009.00426.x
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:To compare the prevalence of disability between migrants and non-migrants at three and 24 months post-injury, and to identify key predictors of post-injury disability among migrants. METHODS:Disability among 2,850 injured participants, including 677 migrants to New Zealand, was measured prospectively using ...
journal_title:Australian and New Zealand journal of public health
pub_type: 杂志文章
doi:10.1111/1753-6405.12927
更新日期:2019-10-01 00:00:00