Abstract:
PURPOSE OF REVIEW:Patients with tetralogy of Fallot are subject to arrhythmic sequelae that substantially impact morbidity and mortality. This review focuses on recent advances in our understanding of the prevalence and types of arrhythmias encountered. Diagnostic and prognostic tools are considered and therapeutic options discussed. RECENT FINDINGS:Multicenter studies have characterized the arrhythmia burden, assessed the impact of implantable cardioverter-defibrillators, and generated a risk score for primary prevention. Left ventricular hemodynamics are increasingly recognized as important contributors to risk for sudden death. Arrhythmia circuits have been characterized, and the impact of pulmonary valve replacement on sudden death has been further questioned. Recent studies cast doubt on the value of right ventricular pacing alone for cardiac resynchronization and provide a rationale for biventricular pacing. SUMMARY:Supraventricular arrhythmias exceed ventricular arrhythmias in prevalence, as atrial fibrillation increases with the aging population. Sudden death is the leading cause of late mortality, although therapeutic advances may alter this profile. Combinations of factors should be considered in risk stratification schemes to select appropriate implantable cardioverter-defibrillator candidates. The role of concomitant intraoperative ablation during pulmonary valve replacement surgery remains to be defined. Cardiac resynchronization therapy, particularly biventricular pacing, offers promise, but requires careful study before widespread implementation.
journal_name
Curr Opin Cardioljournal_title
Current opinion in cardiologyauthors
Le Gloan L,Khairy Pdoi
10.1097/HCO.0b013e328341381asubject
Has Abstractpub_date
2011-01-01 00:00:00pages
60-5issue
1eissn
0268-4705issn
1531-7080journal_volume
26pub_type
杂志文章,评审abstract::For more than three decades, conventional coronary artery bypass grafting (full sternotomy, cardiopulmonary bypass, and cardioplegic arrest) has been the treatment of choice for patients with multi-vessel coronary artery disease. However, neurologic injury secondary to ascending aortic manipulation and systemic inflam...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200109000-00009
更新日期:2001-09-01 00:00:00
abstract::Three-dimensional echocardiography depicts the heart and its structures in their realistic forms. This capability decreases variability both in the quality and the interpretation of complex pathology, among investigators. Therefore, it is likely that the method will become the standard echocardiography examination in ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199811000-00002
更新日期:1998-11-01 00:00:00
abstract::Over the past 30 years, there have been significant pharmacological and technological advances in the treatment of cardiogenic shock. Although most patients who develop cardiogenic shock can be effectively treated with conventional therapy, including inotropic and vasodilating drugs and intra-aortic balloon pumps, a s...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199403000-00013
更新日期:1994-03-01 00:00:00
abstract::Catheter ablation techniques using radiofrequency current have become an accepted form of treatment for a variety of supraventricular tachycardias. The results are excellent in patients with preexcitation syndromes and as the complication rate is low, catheter ablation has become the first line of treatment for these ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199401000-00006
更新日期:1994-01-01 00:00:00
abstract::Angiogenesis, the de novo formation of new vasculature, is a critical response to ischemia that provides neovascularization of ischemic tissues. In therapeutic angiogenesis, an angiogen--a mediator that induces angiogenesis--is delivered to targeted tissues, augmenting the native angiogenic process and enhancing reper...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199911000-00012
更新日期:1999-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Rheumatic heart disease (RHD) affects over 30 million people worldwide. Substantial variation exists in the surgical treatment of patients with RHD. Here, we aim to review the surgical techniques to treat RHD with a focus on rheumatic mitral valve (MV) repair. We introduce novel educational paradigms ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章
doi:10.1097/HCO.0000000000000826
更新日期:2020-12-24 00:00:00
abstract:PURPOSE OF REVIEW:To provide an up to date review of the most recent randomized clinical trials in the field of antithrombotic drugs for cardiovascular diseases. RECENT FINDINGS:In 2017, low-dose anti-Xa treatment added to aspirin proved to be more efficacious than either treatment alone in patients with stable athero...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000530
更新日期:2018-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Many patients requiring cardiac arrhythmia device surgery are on chronic oral anticoagulation therapy. The periprocedural management of their anticoagulation presents a dilemma to physicians, particularly in the subset of patients with moderate-to-high risk of arterial thromboembolic events. Physician...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/hco.0b013e32831bef53
更新日期:2009-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To review the evidence supporting genetic predisposition to coronary artery disease (CAD). Secondly, to elucidate the barriers precluding the identification of genes responsible for CAD. Thirdly, to indicate the new technology now available to overcome these barriers and summarize current progress. R...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32830e6b4e
更新日期:2008-11-01 00:00:00
abstract:PURPOSE OF REVIEW:A healthy lifestyle throughout one's lifespan is the core foundation for both primary and secondary prevention of cardiovascular disease (CVD). Risk-based decisions for pharmacological therapy is added on-top of lifestyle management. Thus, understanding lifestyle-based recommendations is central to CV...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000763
更新日期:2020-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Primary cardiac tumors are a rare disease, which may have severe clinical consequences. Malignant tumors may be misdiagnosed as mixomas, with improper treatment. The aim of this review is to report how to make a differential diagnosis using old and modern tools, the latest trends in tumor classificati...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000335
更新日期:2016-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Transcatheter aortic-valve implantation is a promising new treatment modality for patients with aortic-valve disease, where it may revolutionize the treatment of elderly and high-risk patients. RECENT FINDINGS:The two devices currently available, the Edwards Sapien valve and the Medtronic CoreValve s...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e328335fff4
更新日期:2010-03-01 00:00:00
abstract:PURPOSE OF REVIEW:To illustrate the limitations of predictive risk models in cardiac surgery, highlight the difficulty in interpreting risk-adjusted outcome analysis and discuss the challenges of making clinical decisions based on risk predictions, particularly in high-risk patients. RECENT FINDINGS:Predictive risk mo...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32831217ed
更新日期:2008-11-01 00:00:00
abstract::Myocardial contrast echocardiography (MCE) is an emerging technique in which microbubble contrast agents are visualized in the coronary microvasculature. MCE is an ideal modality for the noninvasive evaluation of acute coronary syndromes because it provides portable, simultaneous assessment of regional wall motion and...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200209000-00003
更新日期:2002-09-01 00:00:00
abstract::Although significant pharmacologic and nonpharmacologic advances in treating hypertension during the last decade have reduced mortality and morbidity, hypertension continues to be a major health concern worldwide. Therefore, the search continues for newer specific pharmacologic treatment of this disorder. This review ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1997-07-01 00:00:00
abstract::Recurrent episodes of unexplained syncope are among the most frequent of complaints referred to physicians for evaluation. Traditional methods of evaluation were both time consuming and expensive and left many patients without a diagnosis. Although neurocardiogenically mediated episodes of hypotension and bradycardia ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199601000-00006
更新日期:1996-01-01 00:00:00
abstract::Cardiovascular disease is the leading cause of death world-wide in populations older than 65 years of age. The variation in cardiovascular mortality rates in this population indicates a substantial potential for effective coronary prevention. The highest risk for development of coronary heart disease is in individuals...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199703000-00017
更新日期:1997-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Thrombus formation, usually on a ruptured atherosclerotic plaque, is pivotal in the pathogenesis of ST segment elevation myocardial infarction (STEMI). This thrombus formation provides the milieu for re-occlusion of the infarct-related artery, the main location of re-infarction post-STEMI. Although ra...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000193
更新日期:2015-07-01 00:00:00
abstract::Although it has been recognized for almost 70 years that there is a substantial genetic component to the pathogenesis of hypertension, only recently have systematic efforts been made to identify the responsible genetically determined mechanisms. In the case of several rare syndromes, spectacular progress has been made...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199609000-00002
更新日期:1996-09-01 00:00:00
abstract::Though tachyarrhythmias occur commonly in patients with the Wolff-Parkinson-White syndrome, many patients remain asymptomatic. Recent studies suggest that routine electrophysiologic testing in these individuals is of limited value. However, electrophysiologic testing remains very helpful in the symptomatic patient fo...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1991-02-01 00:00:00
abstract:PURPOSE OF REVIEW:A recently published study has alerted the cardiovascular community to the existence of a significant and previously unrecognized risk of subclinical valve thrombosis following implantation of surgical and catheter-based bioprosthetic valves. The purpose of this article is to review our current unders...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000373
更新日期:2017-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Ticagrelor is a new, direct acting, reversibly binding P2Y12 receptor antagonist with more potent inhibition of platelets than clopidogrel and which does not require metabolic activation. It was compared with clopidogrel, on a background of the standard of care in a randomized trial in the Platelet In...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1097/HCO.0b013e328353fe7e
更新日期:2012-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this article is to provide an overview of investigational work which has demonstrated the ability of MRI to define abnormalities caused by coronary heart disease. There have been numerous recent advances in the MRI assessment of coronary heart disease which warrant review. RECENT FINDI...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e3283315553
更新日期:2009-11-01 00:00:00
abstract::In the past 2 years, significant advances have been made in class III antiarrhythmic drug therapy. In patients with ventricular arrhythmias and implantable cardioverter defibrillators (ICDs), antiarrhythmic agents are increasingly being used as adjunct therapy to decrease the frequency of ICD discharges. Sotalol was r...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200001000-00006
更新日期:2000-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Heart failure is a major chronic illness with no definitive cure. With improving healthcare and with an aging population in many countries, heart failure has become a common disease of the elderly. Pharmacological management of heart failure in the elderly remains a challenge. The syndrome of heart fa...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000375
更新日期:2017-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Prolonged sitting (sedentary behavior) has deleterious cardiovascular and metabolic correlates; however, little is known about the associations of too much sitting with all-cause and cardiovascular mortality risk. In addition to the adverse effects of total sitting time, the manner in which it is accu...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e3283496605
更新日期:2011-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To provide an update on the management of patients with diabetes mellitus and requiring coronary revascularization. RECENT FINDINGS:Evidence continues to show that patients with diabetes mellitus and ischemic heart disease represent a very high-risk group of patients. Choice of stent appears importan...
journal_title:Current opinion in cardiology
pub_type: 杂志文章
doi:10.1097/HCO.0000000000000421
更新日期:2017-09-01 00:00:00
abstract::Acute mesenteric ischemia (AMI) remains a complex and difficult clinical problem. Such acute ischemia is usually either embolic or thrombotic in nature, but other etiologies exist. The diagnosis of AMI is difficult to establish and often delayed, resulting in irreversible bowel injury that requires intestinal resectio...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199909000-00016
更新日期:1999-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Maximalist low-density lipoprotein (LDL)-lowering strategies such as lowering LDL as much as possible or, alternatively, using the most potent LDL-lowering regimens have become increasingly popular. Almost all attention has focused on the potential advantages of these approaches with little focus on t...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e328353fed5
更新日期:2012-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Coronary artery disease is common in patients with end-stage renal disease (ESRD) on hemodialysis. ESRD patients are prone to atherosclerosis and are likely to present with advanced CAD requiring coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI). RECENT FINDINGS:...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000539
更新日期:2018-09-01 00:00:00