Abstract：
:Patients with multiple sclerosis (MS) frequently experience poor gait and/or cognitive impairment, even in the early stages of the disease. As gait is often executed simultaneously with different cognitive tasks, it is essential to test gait during a cognitive load. Therefore, the main objective of this study was to assess gait and gait variations while simultaneously performing a cognitive task in patients with a clinically isolated syndrome (CIS) suggestive of MS. Fifty-two CIS patients, aged 33.8±0.2 years with an Expanded Disability Status Scale (EDSS) score of 1.7±0.2 were included in the study. The control group consisted of 28 age- and gender-matched healthy subjects. Major spatio-temporal parameters were collected via an electronic walkway (GAITRite electronic walkway system). Participants were instructed to walk under three different conditions: normal, fast, and at a normal pace while performing the modified word list generation (WLG) test. Compared to healthy subjects, the CIS patients' gait was slower and asymmetrical with a wider base of support. The combined walking and cognitive task was expressed in prolonged double support (% gait cycle) and reduced velocity in patients only. As these findings are associated with the very early phase of MS, it appears that the ongoing pathological disease process is already taking place with regard to gait abilities. Since in early MS patients, gait-cognitive dual tasking may lead to an increased risk of falling, this important function should be addressed by physical rehabilitation clinicians.
journal_name
Gait Posturejournal_title
Gait & postureauthors
Kalron A,Dvir Z,Achiron Adoi
10.1016/j.gaitpost.2010.06.002subject
Has Abstractpub_date
2010-07-01 00:00:00pages
332-5issue
3eissn
0966-6362issn
1879-2219pii
S0966-6362(10)00160-8journal_volume
32pub_type
杂志文章相关文献
GAIT & POSTURE文献大全abstract：:In-shoe pressure measurement devices are used in research and clinic to quantify plantar foot pressures. Various devices are available, differing in size, sensor number and type; therefore accuracy and repeatability. Three devices (Medilogic, Tekscan and Pedar) were examined in a 2 day×3 trial design, quantifying inso...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2016.01.026
更新日期：2016-05-01 00:00:00
abstract：:Higher functioning older adults rarely have their balance assessed clinically and as such early decline in balance is not captured. Early identification of declining balance would facilitate earlier intervention and improved management of the ageing process. This study sought to determine if (a) a once off inertial se...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2014.01.003
更新日期：2014-04-01 00:00:00
abstract：INTRODUCTION:In this paper, the Gait Deviation Index (GDI) was used as a convenient method to evaluate pre-to-postoperative gait pattern changes after total hip arthroplasty and identify factors which might be predictive of outcome. DESIGN:Three-dimensional gait data from a randomized clinical trial was used to determ...
journal_title：Gait & posture
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.gaitpost.2015.02.009
更新日期：2015-06-01 00:00:00
abstract：:The purpose of this study was to investigate the kinematics of normal arched and low arched feet in children and use this data to quantify the differences between the two foot types during walking gait. Multi-segment foot motion was measured, using the Heidelberg foot measurement method (HFMM), for 25 normal arched fe...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2010.01.021
更新日期：2010-05-01 00:00:00
abstract：:Informed clinical decision making for femoral and/or tibial de-rotation osteotomies requires accurate measurement of patient function through gait analysis and anatomy through physical examination of bony torsions. Validity of gait analysis has been extensively studied; however, controversy remains regarding the accur...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2013.05.020
更新日期：2014-01-01 00:00:00
abstract：:When investigating whole-body balance in dynamic tasks, adequately tracking the whole-body centre of mass (CoM) or derivatives such as the extrapolated centre of mass (XCoM) can be crucial but add considerable measurement efforts. The aim of this study was to investigate whether reduced kinematic models can still prov...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2017.04.036
更新日期：2017-07-01 00:00:00
abstract：:The redundant kinematic structure of upper extremity (UE) provides it with increased dexterity in activities of daily living (ADL). Most functional tasks during ADL can be implemented in various positions; however, only some routine trajectories are employed in healthy humans. Exploring motion ability and analyzing de...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2010.07.005
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Over the past several years, activity monitors have become very popular in the general population, and due to their low cost and ease of use, are starting to be seen as clinical tools for the assessment of interventions. This presents researchers with the opportunity to better understand how activity, or lac...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2019.06.017
更新日期：2019-07-01 00:00:00
abstract：:In speeding-up normal walking, relative phase between horizontal thorax and pelvis rotations changes from more in-phase (synchronous) to more out-of-phase. In pathology (stroke, Parkinson's disease, low-back pain, pregnancy-related pelvic girdle pain), this often fails to happen. Even in healthy gait, however, these p...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2010.01.019
更新日期：2010-04-01 00:00:00
abstract：:Ankle equinus is the most commonly identified impairment of individuals with spastic hemiplegia (SH). However, it is not clear how equinus at the ankle may contribute to gait deviations at other joints. The purpose of this study was to determine what compensatory gait deviations may occur as a result of an imposed, un...
journal_title：Gait & posture
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.gaitpost.2003.09.005
更新日期：2004-12-01 00:00:00
abstract：:Inertial sensor gait analysis systems (ISGAS) facilitate gait analysis in an unobstructed environment outdoors or outside of a conventional gait laboratory. However, their use in clinical settings and in large scale studies necessitates thorough evaluation of their performance in different settings and populations and...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2011.02.023
更新日期：2011-04-01 00:00:00
abstract：:The aim of this study was to analyze the changes in the standing center of pressure (COP) in a hemiplegic adult population at the beginning and the end of in-patient rehabilitation. The trajectory of the COP was recorded on a force platform and was analyzed in terms of the frequency spectra of the center of gravity (C...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2004.04.011
更新日期：2005-06-01 00:00:00
abstract：:Characterisation of free-living physical activity requires the use of validated and reliable monitors. This study reports an evaluation of the validity and reliability of the activPAL3 monitor for the detection of posture and stepping in both adults and young people. Twenty adults (median 27.6y; IQR22.6y) and 8 young ...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2015.10.020
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Jogging strollers have become increasingly popular as they allow a parent the freedom to run without having to leave their children. Few studies have examined the effects of running with a stroller and no study to date has examined the effects on joint kinematics. The aim of this study was to compare lower l...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2015.10.001
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:To determine the accuracy of clinicians' visual observations of gait disorders following traumatic brain injury (TBI). METHODS:30 ambulant participants (sample of convenience) receiving physiotherapy for mobility limitations following TBI and 25 age, height, weight and sex matched healthy unimpaired controls...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2008.11.005
更新日期：2009-04-01 00:00:00
abstract：INTRODUCTION:Principal component analysis (PCA) has been used to reduce the volume of gait data and can also be used to identify the differences between populations. This approach has not been used on stair climbing gait data. Our objective was to use PCA to compare the gait patterns between young and older adults duri...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2009.10.005
更新日期：2010-02-01 00:00:00
abstract：AIM:To investigate lower limb biomechanical strategy during stair walking in patients with diabetes and patients with diabetic peripheral neuropathy, a population known to exhibit lower limb muscular weakness. METHODS:The peak lower limb joint moments of twenty-two patients with diabetic peripheral neuropathy and thir...
journal_title：Gait & posture
pub_type： 评论,杂志文章
doi：10.1016/j.gaitpost.2016.03.007
更新日期：2016-05-01 00:00:00
abstract：:The physical activity in normal daily life is determined to a large extent by the functional ability of a subject. As a result, the measurement of the physical activity that a subject performs spontaneously could be a useful and objective measurement of disability, particularly in patients with disease-related functio...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2003.07.005
更新日期：2004-10-01 00:00:00
abstract：:Increased ankle muscle coactivation during gait has frequently been observed as an adaptation strategy to compensate for postural instability in adults after stroke. However, it remains unclear whether the muscle coactivation pattern increases or decreases after balance training. The aim of this study was to investiga...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2016.01.006
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Pain in the lower extremities is common among blue-collar workers, with prolonged static standing as a potential risk factor. However, little is known about the association between diurnal accelerometer measures of static standing and pain in the lower extremities, and the potential importance of temporal pa...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2018.10.006
更新日期：2019-01-01 00:00:00
abstract：:The comparative effect of semi-dimensional (SD) and non-dimensional (ND) normalisation on the results of a longitudinal study of gait in 5-12-year old children was investigated. The use of both height and leg length in the normalisation was examined. Only ND analysis could be used to identify subjects with the same ac...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/s0966-6362(02)00062-0
更新日期：2003-02-01 00:00:00
abstract：:Older adults often exhibit high levels of lower extremity muscle co-contraction, which may be the cause or effect of age-related impairments in gait and associated falls. Normal gait requires intact executive function and thus can be slowed by challenging executive resources available to the neuromuscular system throu...
journal_title：Gait & posture
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.gaitpost.2017.01.010
更新日期：2017-03-01 00:00:00
abstract：:Balance-recovery reactions that involve rapid step or reach-to-grasp movements are prevalent and functionally important responses to instability. Successful use of these reactions to recover balance in daily life requires a capacity to modulate the reaction to deal with the continual variation in environmental constra...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2008.08.011
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:Gait asymmetry is an important characteristic often studied in stroke patients. Several methods have been used to define gait asymmetry using joint angles. However, these methods may require normative data from healthy individuals as reference points. This study used normalized cross-correlation (CCnorm) to ...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2020.05.042
更新日期：2020-07-01 00:00:00
abstract：:Traditional measures of postural stability consider movement of the center of pressure (COP) or the center of mass (COM) without regard to the boundary of support (BOS). A potentially more appropriate measure is postural time-to-contact (TtC) which defines the spatio-temporal proximity of the COM or COP to the BOS. Gi...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2011.09.103
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:Knee osteoarthritis (OA) is a degenerative joint disease that affects millions of individuals each year. Several biomechanical variables during walking have been identified as risk factors for developing knee OA, including the peak external knee adduction moment (KAM) and the knee flexion angle at initial co...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2020.10.030
更新日期：2021-01-01 00:00:00
abstract：:The purpose of this cross-sectional study was to investigate whether gender differences exist in postural reaction when examining response time and amplitude of normalized ground reaction force (GRF) in subjects with low back pain (LBP). Alterations in GRF following sudden perturbations have led to an increased awaren...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2008.09.012
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:Anticipatory postural adjustments (APAs) occur in the trunk during tasks such as rapid limb movement and are impaired in individuals with musculoskeletal and neurological dysfunction. To understand APA impairment, it is important to first determine if APAs can be measured reliably and which characteristics o...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2020.01.003
更新日期：2020-02-01 00:00:00
abstract：:The purpose of this paper is to present a reliable algorithm to discriminate between left/right foot contact using an accelerometer located over the lower lumbar spine. With the given accelerometer frame orientation, the side detection algorithm, based on the sign of the derivative of the sinusoidal shape obtained fro...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2015.05.021
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Mobility and balance in Huntington's disease (HD) are currently assessed in the clinic with three items from the unified Huntington's disease rating scale (UHDRS): walk, tandem and pull tests. These tests may not be optimal because they are scored on an ordinal scale and do not test anticipatory balance. We ...
journal_title：Gait & posture
pub_type： 杂志文章
doi：10.1016/j.gaitpost.2008.11.002
更新日期：2009-04-01 00:00:00
