Contrasting landscape epidemiology of two sympatric rabies virus strains.

Abstract:

:Viral strain evolution and disease emergence are influenced by anthropogenic change to the environment. We investigated viral characteristics, host ecology, and landscape features in the rabies-striped skunk disease system of the central Great Plains to determine how these factors interact to influence disease emergence. We amplified portions of the N and G genes of rabies viral RNA from 269 samples extracted from striped skunk brains throughout the distribution of two different rabies strains for which striped skunks were the reservoir. Because the distribution of these two strains overlapped on the landscape and were present in the same host population, we could evaluate how viral properties influenced epidemiological patterns in the area of sympatry. We found that South Central Skunk rabies (SCSK) exhibited intense purifying selection and high infectivity, which are both characteristics of an epizootic virus. Conversely, North Central Skunk rabies (NCSK) exhibited relaxed purifying selection and comparatively lower infectivity, suggesting the presence of an enzootic virus. The host population in the area of sympatry was highly admixed, and skunks among allopatric and sympatric areas had similar effective population sizes. Spatial analysis indicated that landscape features had minimal influence on NCSK movement across the landscape, but those same features were partial barriers to the spread of SCSK. We conclude that NCSK and SCSK have different epidemiological properties that interact differently with both host and landscape features to influence rabies spread in the central Great Plains. We suggest a holistic approach for future studies of emerging infectious diseases that includes studies of viral properties, host characteristics, and spatial features.

journal_name

Mol Ecol

journal_title

Molecular ecology

authors

Barton HD,Gregory AJ,Davis R,Hanlon CA,Wisely SM

doi

10.1111/j.1365-294X.2010.04668.x

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

2725-38

issue

13

eissn

0962-1083

issn

1365-294X

pii

MEC4668

journal_volume

19

pub_type

杂志文章
  • Evolutionary genetics of a defensive facultative symbiont of insects: exchange of toxin-encoding bacteriophage.

    abstract::The facultative endosymbiont of aphids, Hamiltonella defensa, kills parasitoid wasp larvae, allowing aphid hosts to survive and reproduce. This protection may depend on toxins that are encoded by the genomes of H. defensa and of its bacteriophage (APSE). Strains of H. defensa vary in degree of protection conferred upo...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2007.03616.x

    authors: Degnan PH,Moran NA

    更新日期:2008-02-01 00:00:00

  • Intrinsic incompatibilities evolving as a by-product of divergent ecological selection: Considering them in empirical studies on divergence with gene flow.

    abstract::The possibility of intrinsic barriers to gene flow is often neglected in empirical research on local adaptation and speciation with gene flow, for example when interpreting patterns observed in genome scans. However, we draw attention to the fact that, even with gene flow, divergent ecological selection may generate i...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/mec.14147

    authors: Kulmuni J,Westram AM

    更新日期:2017-06-01 00:00:00

  • Integrating QTL mapping and genome scans towards the characterization of candidate loci under parallel selection in the lake whitefish (Coregonus clupeaformis).

    abstract::As natural selection must act on underlying genetic variation, discovering the number and location of loci under the influence of selection is imperative towards understanding adaptive divergence in evolving populations. Studies employing genome scans have hypothesized that the action of divergent selection should red...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2004.02396.x

    authors: Rogers SM,Bernatchez L

    更新日期:2005-02-01 00:00:00

  • Genetic diversity and population structure of an insular tree, Santalum austrocaledonicum in New Caledonian archipelago.

    abstract::We present a study of the genetic diversity and structure of a tropical tree in an insular system. Santalum austrocaledonicum is endemic to the archipelago of New Caledonia and is exploited for oil extraction from heartwood. A total of 431 individuals over 17 populations were analysed for eight polymorphic microsatell...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2005.02576.x

    authors: Bottin L,Verhaegen D,Tassin J,Olivieri I,Vaillant A,Bouvet JM

    更新日期:2005-06-01 00:00:00

  • Stasipatric speciation: resurrecting a system to bury a hypothesis?

    abstract::The process of speciation remains a fundamental topic in evolutionary biology. Numerous models of speciation have been proposed and they are as diverse and colourful as the scientists who conceived them (Coyne & Orr 2004). One of the more controversial theories has been the 'stasipatric speciation' model, proposed by ...

    journal_title:Molecular ecology

    pub_type: 评论,杂志文章

    doi:10.1111/j.1365-294X.2009.04278.x

    authors: Kearney M,Hewitt G

    更新日期:2009-08-01 00:00:00

  • Epigenetic variation predicts regional and local intraspecific functional diversity in a perennial herb.

    abstract::The ecological significance of epigenetic variation has been generally inferred from studies on model plants under artificial conditions, but the importance of epigenetic differences between individuals as a source of intraspecific diversity in natural plant populations remains essentially unknown. This study investig...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/mec.12911

    authors: Medrano M,Herrera CM,Bazaga P

    更新日期:2014-10-01 00:00:00

  • Nonallopatric and parallel origin of local reproductive barriers between two snail ecotypes.

    abstract::Theory suggests that speciation is possible without physical isolation of populations (hereafter, nonallopatric speciation), but recent nonallopatric models need the support of irrefutable empirical examples. We collected snails (Littorina saxatilis) from three areas on the NW coast of Spain to investigate the populat...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2004.02330.x

    authors: Rolán-Alvarez E,Carballo M,Galindo J,Morán P,Fernández B,Caballero A,Cruz R,Boulding EG,Johannesson K

    更新日期:2004-11-01 00:00:00

  • Perspective.

    abstract::Reef corals are especially sensitive to environmental change since their survival is dependent on a delicate balance between the coral host and its algal endosymbiont. Predicting the responses of reef ecosystems to global climate change requires a detailed understanding of the diversity of both partners in this symbio...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2007.03254.x

    authors: van Oppen MJ

    更新日期:2007-03-01 00:00:00

  • Inbreeding effects on gene-specific DNA methylation among tissues of Chinook salmon.

    abstract::Inbreeding depression is the loss of fitness resulting from the mating of genetically related individuals. Traditionally, the study of inbreeding depression focused on genetic effects, although recent research has identified DNA methylation as also having a role in inbreeding effects. Since inbreeding depression and D...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/mec.13777

    authors: Venney CJ,Johansson ML,Heath DD

    更新日期:2016-09-01 00:00:00

  • Protein elemental sparing and codon usage bias are correlated among bacteria.

    abstract::Highly expressed proteins can exhibit relatively small material costs, in terms of the quantities of carbon (C), nitrogen (N) or sulphur (S) atoms they contain. This 'elemental sparing' probably reflects selection to reduce the quantities of potentially growth-limiting elements in abundant proteins, but the evolutiona...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2012.05529.x

    authors: Bragg JG,Quigg A,Raven JA,Wagner A

    更新日期:2012-05-01 00:00:00

  • The discovery of Antarctic RNA viruses: a new game changer.

    abstract::Antarctic ecosystems are dominated by micro-organisms, and viruses play particularly important roles in the food webs. Since the first report in 2009 (López-Bueno et al. ), 'omic'-based studies have greatly enlightened our understanding of Antarctic aquatic microbial diversity and ecosystem function (Wilkins et al. ; ...

    journal_title:Molecular ecology

    pub_type: 评论,杂志文章

    doi:10.1111/mec.13387

    authors: Cavicchioli R,Erdmann S

    更新日期:2015-10-01 00:00:00

  • Genetic diversity in water frog hybrids (Pelophylax esculentus) varies with population structure and geographic location.

    abstract::Pelophylax esculentus is a hybridogenetic frog originating from matings between P. ridibundus (RR) and P. lessonae (LL). Typically, diploid hybrids (LR) live in sympatry with one of their parental species, upon which they depend for successful reproduction. In parts of their range, however, pure hybrid populations can...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2010.04603.x

    authors: Arioli M,Jakob C,Reyer HU

    更新日期:2010-05-01 00:00:00

  • Indirect genetic estimates of breeding population size in the polyploid green sturgeon (Acipenser medirostris).

    abstract::The utility of genetic measures for kinship reconstruction in polysomic species is not well evaluated. We developed a framework to test hypotheses about estimating breeding population size indirectly from collections of outmigrating green sturgeon juveniles. We evaluated a polysomic dataset, in allelic frequency and p...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2010.04533.x

    authors: Israel JA,May B

    更新日期:2010-03-01 00:00:00

  • Hybridization and the porous genome: patterns of isolation and introgression in manakins.

    abstract::How does one species become two? What is the relative importance of selection vs. drift? How many genes are involved, what are their effect sizes and where are they located in the genome? The answers to these questions will inevitably vary from one species to another, but by addressing these questions in a diverse arr...

    journal_title:Molecular ecology

    pub_type: 评论,杂志文章

    doi:10.1111/mec.12314

    authors: Yeaman S

    更新日期:2013-06-01 00:00:00

  • Variation for neutral markers is correlated with variation for quantitative traits in the plant pathogenic fungus Mycosphaerella graminicola.

    abstract::We compared genetic variation and population differentiation at RFLP marker loci with seven quantitative characters including fungicide resistance, temperature sensitivity, pycnidial size, pycnidial density, colony size, percentage of leaves covered by pycnidia (PLACP) and percentage of leaves covered by lesions (PLAC...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2005.02638.x

    authors: Zhan J,Linde CC,Jürgens T,Merz U,Steinebrunner F,McDonald BA

    更新日期:2005-08-01 00:00:00

  • Host and geographical factors influence the thermal niche of enteric bacteria isolated from native Australian mammals.

    abstract::The thermal profiles of 118 bacterial strains, representing six species of the family Enterobacteriaceae, isolated from a variety of native Australian mammals were determined under in vitro conditions. Each of the bacterial species had a unique thermal profile and differed in their minimum or maximum temperature for g...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1046/j.0962-1083.2001.01384.x

    authors: Okada S,Gordon DM

    更新日期:2001-10-01 00:00:00

  • Controlling false discoveries in genome scans for selection.

    abstract::Population differentiation (PD) and ecological association (EA) tests have recently emerged as prominent statistical methods to investigate signatures of local adaptation using population genomic data. Based on statistical models, these genomewide testing procedures have attracted considerable attention as tools to id...

    journal_title:Molecular ecology

    pub_type: 杂志文章,评审

    doi:10.1111/mec.13513

    authors: François O,Martins H,Caye K,Schoville SD

    更新日期:2016-01-01 00:00:00

  • Using multilevel models to identify drivers of landscape-genetic structure among management areas.

    abstract::Landscape genetics offers a powerful approach to understanding species' dispersal patterns. However, a central obstacle is to account for ecological processes operating at multiple spatial scales, while keeping research outcomes applicable to conservation management. We address this challenge by applying a novel multi...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/mec.12359

    authors: Dudaniec RY,Rhodes JR,Worthington Wilmer J,Lyons M,Lee KE,McAlpine CA,Carrick FN

    更新日期:2013-07-01 00:00:00

  • Ear mite infection is associated with altered microbial communities in genetically depauperate Santa Catalina Island foxes (Urocyon littoralis catalinae).

    abstract::The host-associated microbiome is increasingly recognized as a critical player in health and immunity. Recent studies have shown that disruption of commensal microbial communities can contribute to disease pathogenesis and severity. Santa Catalina Island foxes (Urocyon littoralis catalinae) present a compelling system...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/mec.15325

    authors: DeCandia AL,Brenner LJ,King JL,vonHoldt BM

    更新日期:2020-04-01 00:00:00

  • No evidence for accumulation of deleterious mutations and fitness degradation in clonal fish hybrids: Abandoning sex without regrets.

    abstract::Despite its inherent costs, sexual reproduction is ubiquitous in nature, and the mechanisms to protect it from a competitive displacement by asexuality remain unclear. Popular mutation-based explanations, like the Muller's ratchet and the Kondrashov's hatchet, assume that purifying selection may not halt the accumulat...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/mec.15539

    authors: Kočí J,Röslein J,Pačes J,Kotusz J,Halačka K,Koščo J,Fedorčák J,Iakovenko N,Janko K

    更新日期:2020-08-01 00:00:00

  • Paternal effects in a wild-type zebrafish implicate a role of sperm-derived small RNAs.

    abstract::While the importance of maternal effects has long been appreciated, a growing body of evidence now points to the paternal environment having an important influence on offspring phenotype. Indeed, research on rodent models suggests that paternal stress leaves an imprint on the behaviour and physiology of offspring via ...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/mec.15505

    authors: Ord J,Heath PR,Fazeli A,Watt PJ

    更新日期:2020-07-01 00:00:00

  • Colonization and dispersal in a social species, the Bechstein's bat (Myotis bechsteinii).

    abstract::Metapopulation genetic models consider that colonization and dispersal are distinct behaviours. However, whether colonization and dispersal indeed reflect different biological processes in nature is unclear. One possibility to test this assumption is to assess patterns of autosomal and mitochondrial genetic structure ...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2005.02719.x

    authors: Kerth G,Petit E

    更新日期:2005-11-01 00:00:00

  • Diversity and divergence patterns in regulatory genes suggest differential gene flow in recently derived species of the Hawaiian silversword alliance adaptive radiation (Asteraceae).

    abstract::The impact of gene flow and population size fluctuations in shaping genetic variation during adaptive radiation, at both the genome-wide and gene-specific levels, is very poorly understood. To examine how historical population size and gene flow patterns within and between loci have influenced lineage divergence in th...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2007.03445.x

    authors: Lawton-Rauh A,Robichaux RH,Purugganan MD

    更新日期:2007-10-01 00:00:00

  • Evolutionary mechanisms shaping the genetic population structure of marine fishes; lessons from the European flounder (Platichthys flesus L.).

    abstract::A number of evolutionary mechanisms have been suggested for generating low but significant genetic structuring among marine fish populations. We used nine microsatellite loci and recently developed methods in landscape genetics and coalescence-based estimation of historical gene flow and effective population sizes to ...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2007.03367.x

    authors: Hemmer-Hansen J,Nielsen EE,Grønkjaer P,Loeschcke V

    更新日期:2007-08-01 00:00:00

  • Effects of soil preservation for biodiversity monitoring using environmental DNA.

    abstract::Environmental DNA (eDNA) metabarcoding is becoming a key tool for biodiversity monitoring over large geographical or taxonomic scales and for elusive taxa such as soil organisms. Increasing sample sizes and interest in remote or extreme areas often require the preservation of soil samples and thus deviations from opti...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/mec.15674

    authors: Guerrieri A,Bonin A,Münkemüller T,Gielly L,Thuiller W,Francesco Ficetola G

    更新日期:2020-10-08 00:00:00

  • Estimating population divergence time and phylogeny from single-nucleotide polymorphisms data with outgroup ascertainment bias.

    abstract::The inference of population divergence times and branching patterns is of fundamental importance in many population genetic analyses. Many methods have been developed for estimating population divergence times, and recently, there has been particular attention towards genome-wide single-nucleotide polymorphisms (SNP) ...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2011.05413.x

    authors: Wang Y,Nielsen R

    更新日期:2012-02-01 00:00:00

  • Patterns of hybridization and population genetic structure in the terrestrial orchids Liparis kumokiri and Liparis makinoana (Orchidaceae) in sympatric populations.

    abstract::We investigated the potential for gene flow and genetic assimilation via hybridization between common and rare species of the terrestrial orchid genus Liparis, focusing specifically on sympatric and allopatric populations of the common Liparis kumokiri and the rare Liparis makinoana. We utilized analyses of genetic di...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/j.1365-294X.2005.02738.x

    authors: Chung MY,Nason JD,Chung MG

    更新日期:2005-12-01 00:00:00

  • Extreme specificity in epiparasitic Monotropoideae (Ericaceae): widespread phylogenetic and geographical structure.

    abstract::The Monotropoideae (Ericaceae) are nonphotosynthetic plants that obtain fixed carbon from their fungal mycorrhizal associates. To infer the evolutionary history of this symbiosis we identified both the plant and fungal lineages involved using a molecular phylogenetic approach to screen 331 plants, representing 10 of t...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1046/j.1365-294x.2001.01358.x

    authors: Bidartondo MI,Bruns TD

    更新日期:2001-09-01 00:00:00

  • Planarian mitochondria sequence heterogeneity: relationships between the type of cytochrome c oxidase subunit I gene sequence, karyotype and genital organ.

    abstract::Freshwater planarians Dugesia japonica from three localities were examined for cytochrome c oxidase subunit I (COI) gene sequence, karyotype and the presence of genital organ. The planarians from Mt Fujiwara in Japan were composed of two different groups; one revealed inter- and intraindividual COI gene heterogeneity,...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1046/j.1365-294x.1997.00162.x

    authors: Bessho Y,Tamura S,Hori H,Tanaka H,Ohama T,Osawa S

    更新日期:1997-02-01 00:00:00

  • The coral immune response facilitates protection against microbes during tissue regeneration.

    abstract::Increasing physical damage on coral reefs from predation, storms and anthropogenic disturbances highlights the need to understand the impact of injury on the coral immune system. In this study, we examined the regulation of the coral immune response over 10 days following physical trauma artificially inflicted on in s...

    journal_title:Molecular ecology

    pub_type: 杂志文章

    doi:10.1111/mec.13257

    authors: van de Water JA,Ainsworth TD,Leggat W,Bourne DG,Willis BL,van Oppen MJ

    更新日期:2015-07-01 00:00:00