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Cost-effectiveness research on preventive interventions: a survey of the publications in 2008.

Abstract：

BACKGROUND:In recent years the literature regarding the cost-effectiveness of disease prevention and health promotion has grown exponentially. Aim of this study is to investigate: (i) how many and what type of economic evaluations have been published in 2008, (ii) the diseases or health problems World Health Organization International Classification of Diseases 10 chapters the economic evaluations of preventive interventions focus on, in relation to the global burden of disease and (iii) the cost-effectiveness of these interventions. METHODS:Literature study of economic evaluations on preventive interventions in PubMed and Scopus. RESULTS:In 2008, 232 economic evaluations of preventive interventions have been published. Of these studies, 75% (n = 175) used costs per (Quality Adjusted) Life Year [(QA)LY] gained as outcome measure. Most economic evaluations focus on the prevention of infectious diseases (31.5%, n = 73) and cancers (21%, n = 49) Infectious diseases are responsible for the highest global burden of disease (19.8%), followed by mental and behavioural disorders (11.7%). Of the included economic evaluations, 80% remained below a threshold of €50 000 and 60% below €20 000 per (QA)LY. CONCLUSION:This study shows that many economic evaluations of preventive interventions use a generic outcome measure. This adds to the comparability of different studies on the cost-effectiveness of prevention. Although the focus of published economic evaluations in general corresponds well with those diseases that cause a large share of the world's burden of disease, mental and behavioural diseases and diseases of the respiratory system remain underrepresented. Finally, it appears that the vast majority of published economic evaluations of preventive measures show favourable cost-effectiveness levels.

journal_name

Eur J Public Health

journal_title

European journal of public health

authors

van Gils PF,Tariq L,Verschuuren M,van den Berg M

doi

10.1093/eurpub/ckq069

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

260-4

issue

2

eissn

1101-1262

issn

1464-360X

pii

ckq069

journal_volume

21

pub_type

杂志文章

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