HLA-A alleles and the risk of cervical squamous cell carcinoma in Japanese women.

Abstract:

BACKGROUND:We conducted a case-control study to examine the relationship between human leukocyte antigen-A (HLA-A) allele polymorphism and the pathogenesis of cervical neoplasia among Japanese women. METHODS:A total of 119 patients with invasive cervical squamous cell carcinoma were compared to 119 age- and menopausal status-matched non-cancer controls. Blood samples were taken from all cases and controls and lifestyle information was collected by means of a self-administered questionnaire. The estimated impact of HLA-A alleles on cervical cancer risk was evaluated by unconditional logistic regression models. RESULTS:The frequency of HLA-A(*)0206 among cases was significantly lower than among controls (P = 0.006). There was an inverse association between A(*)0206 and cervical cancer risk (odds ratio [OR] = 0.31, 95% confidence interval [95% CI] = 0.15 to 0.65, P = 0.002), and a positive association for HLA-A(*)2402 (OR = 1.76, 95% CI = 1.00 to 3.09, P = 0.048). After correction for multiple comparisons, A(*)0206 was significantly associated with reduced cervical cancer risk (corrected P = 0.036). Furthermore, the inverse association between A(*)0206 and cervical cancer risk was independent of smoking status (never smoker: OR = 0.37, 95% CI = 0.15 to 0.90; ever smoker: OR = 0.23, 95% CI = 0.06 to 0.89). CONCLUSIONS:There was an inverse association between HLA-A(*)0206 and cervical cancer risk among Japanese women, which suggests that HLA-A polymorphism influences cervical cancer risk. Further investigation in other populations is thus warranted.

journal_name

J Epidemiol

journal_title

Journal of epidemiology

authors

Hosono S,Kawase T,Matsuo K,Watanabe M,Kajiyama H,Hirose K,Suzuki T,Kidokoro K,Ito H,Nakanishi T,Yatabe Y,Hamajima N,Kikkawa F,Tajima K,Tanaka H

doi

10.2188/jea.je20090155

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

295-301

issue

4

eissn

0917-5040

issn

1349-9092

pii

JST.JSTAGE/jea/JE20090155

journal_volume

20

pub_type

杂志文章
  • Does laughter predict onset of functional disability and mortality among older Japanese adults? the JAGES prospective cohort study.

    abstract:BACKGROUND:While laughter is broadly recognized as a good medicine, a potential preventive effect of laughter on disability and death is still being debated. Accordingly, we investigated the association between the frequency of laughter and onset of functional disability and all-cause mortality among the older adults i...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20200051

    authors: Tamada Y,Takeuchi K,Yamaguchi C,Saito M,Ohira T,Shirai K,Kondo K

    更新日期:2020-05-16 00:00:00

  • High blood pressure in obese and nonobese Japanese children: blood pressure measurement is necessary even in nonobese Japanese children.

    abstract:BACKGROUND:Although the prevalences of obesity and hypertension (HT) are increasing in children, there have been few epidemiological studies of HT in Japanese children. We evaluated the prevalences of HT and high-normal blood pressure (HNBP), and examined the relationship between blood pressure (BP) and body mass index...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20090207

    authors: Shirasawa T,Shimada N,Ochiai H,Ohtsu T,Hoshino H,Nishimura R,Morimoto A,Tajima N,Kokaze A

    更新日期:2010-01-01 00:00:00

  • Use of seasonal influenza virus titer and respiratory symptom score to estimate effective human contact rates.

    abstract:BACKGROUND:We linked viral titers and respiratory symptom scores for seasonal influenza to estimate the effective contact rate among schoolchildren. METHODS:We analyzed 274 diary-based questionnaires. In addition, 2 sets of influenza data from published studies were used to investigate the relationship between viral t...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20110146

    authors: Chen SC,You SH,Ling MP,Chio CP,Liao CM

    更新日期:2012-01-01 00:00:00

  • A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lung.

    abstract::The 8-oxoguanine DNA glycosylase (OGG1) repairs DNA by removing 8-hydroxyguanine, a highly mutagenic oxidative DNA adduct. Recently, the gene for OGG1 was cloned and several polymorphisms have been reported. Because environmental carcinogens produce 8-hydroxyguanine residues that potentially cause oncogenic mutations ...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.12.258

    authors: Ito H,Hamajima N,Takezaki T,Matsuo K,Tajima K,Hatooka S,Mitsudomi T,Suyama M,Sato S,Ueda R

    更新日期:2002-05-01 00:00:00

  • High Tomato and Tomato Product Consumption is Protective Against the Decline in Handgrip Strength Among Japanese Adults: The Oroshisho Study.

    abstract:BACKGROUND:There is scarce epidemiological evidence regarding the relationships of the consumption of different types of vegetables or fruits with change in skeletal muscle strength. We prospectively examined the relationships among Japanese adults, using handgrip strength to assess skeletal muscle strength. METHODS:A...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20170029

    authors: Ren Z,Huang C,Momma H,Cui Y,Niu K,Sugiyama S,Nanno M,Nagatomi R

    更新日期:2018-09-05 00:00:00

  • Baseline cardiovascular risk factors and stroke mortality by municipality population size in a 19-year follow-up study-NIPPON DATA80.

    abstract::The urban-rural difference in cardiovascular risk factors and stroke mortality throughout Japan was examined in a cohort by using hierarchical data structure. The subjects were 9,309 men and women aged > or = 30 years who were residents of 294 areas in 211 municipalities of Japan in 1980; they were followed up until 1...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je2008034

    authors: Nishi N

    更新日期:2008-01-01 00:00:00

  • Timeliness and completeness of measles vaccination among children in rural areas of Guangxi, China: A stratified three-stage cluster survey.

    abstract:BACKGROUND:Large-scale outbreaks of measles occurred in 2013 and 2014 in rural Guangxi, a region in Southwest China with high coverage for measles-containing vaccine (MCV). This study aimed to estimate the timely vaccination coverage, the timely-and-complete vaccination coverage, and the median delay period for MCV amo...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.je.2016.08.006

    authors: Tang X,Geater A,McNeil E,Zhou H,Deng Q,Dong A

    更新日期:2017-07-01 00:00:00

  • Factors affecting sustainable iodine deficiency elimination in Pakistan: A global perspective.

    abstract::Iodine deficiency remains a considerable challenge worldwide, even after decades of efforts to address the problem. The aim of this review is to present the current situation in historically iodine-deficient Pakistan regarding iodine nutritional status and place it in a global perspective. We collected relevant articl...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.je.2016.04.003

    authors: Khattak RM,Khattak MNK,Ittermann T,Völzke H

    更新日期:2017-06-01 00:00:00

  • Effects of maternal 5,10-methylenetetrahydrofolate reductase C677T and A1298C Polymorphisms and tobacco smoking on infant birth weight in a Japanese population.

    abstract:BACKGROUND:Intracellular folate hemostasis depends on the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene. Because 5,10-MTHFR 677TT homozygosity and tobacco smoking are associated with low folate status, we tested the hypothesis that smoking in mothers with 5,10-MTHFR C677T or A1298C polymorphisms would be indepe...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20110039

    authors: Yila TA,Sasaki S,Miyashita C,Braimoh TS,Kashino I,Kobayashi S,Okada E,Baba T,Yoshioka E,Minakami H,Endo T,Sengoku K,Kishi R

    更新日期:2012-01-01 00:00:00

  • Health status, life habits, and social background among the JPHC study participants at baseline survey. Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases.

    abstract::A self-reported questionnaire on the health status, life habits, and social background was conducted at baseline in the Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases (JPHC study). This report presents the outcome of the study regarding past or family history of various diseas...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.11.6sup_57

    authors: Konishi M,Kondou H,Okada K

    更新日期:2001-10-01 00:00:00

  • Proteinuria and Reduced Estimated Glomerular Filtration Rate are Independently Associated With Lower Cognitive Abilities in Apparently Healthy Community-Dwelling Elderly Men in Japan: A Cross-sectional Study.

    abstract:BACKGROUND:The association of proteinuria and reduced estimated glomerular filtration rate (eGFR) with cognition needs more clarification. We cross-sectionally examined whether proteinuria and reduced eGFR, even in moderate stages, were independently associated with lower cognition in a community-based sample of elderl...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20180258

    authors: Fujiyoshi A,Miura K,Ohkubo T,Miyagawa N,Saito Y,Miyazawa I,Shiino A,Kadota A,Kadowaki S,Hisamatsu T,Torii S,Takashima N,Tooyama I,Ueshima H

    更新日期:2020-06-05 00:00:00

  • Asthma-like disease in the children living in the neighborhood of Mt. Sakurajima.

    abstract::We conducted self-administered questionnaire surveys of school children living in the vicinity of Mt. Sakurajima using ATS-DLD questionnaire. In this paper, we report the results of analysis comparing the proportion of children with asthma-like disease in the area exposed to the volcanic ash and gases released by Mt. ...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.9.27

    authors: Uda H,Akiba S,Hatano H,Shinkura R

    更新日期:1999-02-01 00:00:00

  • Determining the Optimal Number of Wearing-Days Given a Fixed Number of Accelerometers in Population-Level Study.

    abstract:BACKGROUND:In research using accelerometers to measure physical activity, the number of accelerometers that can be utilized in a study and the study duration are both constrained. It means that increasing the number of accelerometer wearing days for all subjects leads to a decrease in the total number of participants t...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20180095

    authors: Lee PH

    更新日期:2019-11-05 00:00:00

  • The Ohsaki Cohort 2006 Study: design of study and profile of participants at baseline.

    abstract:BACKGROUND:Large-scale cohort studies conducted in Japan do not always include psychosocial factors as exposures. In addition, such studies sometimes fail to satisfactorily evaluate disability status as an outcome. METHODS:This prospective cohort study comprised 49 603 (22 438 men and 27 165 women) community-dwelling ...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20090093

    authors: Kuriyama S,Nakaya N,Ohmori-Matsuda K,Shimazu T,Kikuchi N,Kakizaki M,Sone T,Sato F,Nagai M,Sugawara Y,Tomata Y,Akhter M,Higashiguchi M,Fukuchi N,Takahashi H,Hozawa A,Tsuji I

    更新日期:2010-01-01 00:00:00

  • The lack of relationship between an endothelin-1 gene polymorphism (Ala288ser) and incidence of hypertension: a retrospective cohort study among Japanese workers.

    abstract:BACKGROUND:Some case-control association studies revealed the relationship between some endothelin-1 (ET-1) gene polymorphisms and blood pressure. Because no report was available about the relationship between any ET-1 gene polymorphism and incidence of hypertension, we examined the relationship between novel ET-1 gene...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.14.129

    authors: Kaetsu A,Kishimoto T,Osaki Y,Okamoto M,Fukumoto S,Kurozawa Y

    更新日期:2004-07-01 00:00:00

  • Seasonal variation in epidemiology of Kawasaki disease-related coronary artery abnormalities in Japan, 1999-2017.

    abstract:BACKGROUND:Epidemiological studies show a U-shaped tendency in Kawasaki disease (KD)-related coronary artery abnormalities (CAAs) across age categories. Since studies suggest seasonal variations in KD onset, this study aimed to clarify the epidemiologic features of CAAs, considering the seasons of KD-occurrence. METHO...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20190189

    authors: Kitano N,Takeuchi T,Suenaga T,Kakimoto N,Naka A,Shibuta S,Tachibana S,Takekoshi N,Suzuki T,Tsuchihashi T,Yamano T,Akasaka T,Suzuki H

    更新日期:2020-02-22 00:00:00

  • Validity and reproducibility of a self-administered food frequency questionnaire used in the baseline survey of the JPHC Study Cohort I.

    abstract::We examined the validity and reproducibility of a 44-item food frequency questionnaire used in a baseline survey of the Japan Public Health Center-Based Prospective Study Cohort I conducted in February 1990. Subjects were 94 men and 107 women selected on a voluntary basis among respondents to the baseline survey. Four...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.2188/jea.13.1sup_125

    authors: Tsubono Y,Kobayashi M,Sasaki S,Tsugane S,JPHC.

    更新日期:2003-01-01 00:00:00

  • Japan collaborative cohort study for evaluation of cancer risk sponsored by monbusho (JACC study).

    abstract::This paper primarily aimed to overview the rationale for initiating the Japan Collaborative Cohort Study for Evaluation of Cancer Risk Sponsored by Monbusho (Ministry of Education, Science, Sports and Culture of Japan) (JACC Study), by comparing socio-demographic and nutritional changes that were witnessed between 196...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.11.144

    authors: Ohno Y,Tamakoshi A,JACC Study Group.

    更新日期:2001-07-01 00:00:00

  • Menstrual and reproductive factors and risk of lung cancer among Chinese women, Eastern Gansu Province, 1994-1998.

    abstract::There are suggestions that women have higher relative risks of lung cancer than men given similar levels of tobacco exposure, implying that sex-related hormones may influence lung cancer risk. We evaluated the association between lung cancer risk and menstrual and reproductive factors on a subset of self-responding fe...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.13.22

    authors: Brenner AV,Wang Z,Kleinerman RA,Lei S,Metayer C,Wang W,Lubin JH

    更新日期:2003-01-01 00:00:00

  • Impact of Caregiver Type for 3-Year-Old Children on Subsequent Between-Meal Eating Habits and Being Overweight From Childhood to Adulthood: A 20-Year Follow-up of the Ibaraki Children's Cohort (IBACHIL) Study.

    abstract:BACKGROUND:Because of the increasing number of mothers who continue to work after childbirth, participation in childcare has diversified. However, the impact of the main caregiver on children's habits has not been determined. We sought to examine the effect of caregiver differences on childhood habituation of between-m...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20140078

    authors: Sata M,Yamagishi K,Sairenchi T,Ikeda A,Irie F,Watanabe H,Iso H,Ota H

    更新日期:2015-01-01 00:00:00

  • Pathophysiologic mechanisms of obesity and related metabolic disorders: an epidemiologic study using questionnaire and serologic biomarkers.

    abstract:BACKGROUND:It is still unclear whether individuals with the same degree of obesity but different weight histories since young adulthood have different insulin concentration, prevalence of metabolic syndrome components and their clustering. METHODS:A cross-sectional study was conducted on 3,399 (for weight difference a...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.17.141

    authors: Yatsuya H

    更新日期:2007-09-01 00:00:00

  • The relationship between Asian dust events and out-of-hospital cardiac arrests in Japan.

    abstract:BACKGROUND:Asian dust events are caused by dust storms that originate in the deserts of China and Mongolia and drift across East Asia. We hypothesized that the dust events would increase incidence of out-of-hospital cardiac arrests by triggering acute events or exacerbating chronic diseases. METHODS:We analyzed the Ut...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20140179

    authors: Nakamura T,Hashizume M,Ueda K,Kubo T,Shimizu A,Okamura T,Nishiwaki Y

    更新日期:2015-01-01 00:00:00

  • Does hyperuricemia affect mortality? A prospective cohort study of Japanese male workers.

    abstract::A positive association between hyperuricemia and cardiovascular disease has been reported, but no study has evidenced yet the precise role of serum uric acid in the development of cardiovascular disease. In addition, no epidemiological studies have so far documented a decreased risk of cancer among people with hyperur...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.10.403

    authors: Tomita M,Mizuno S,Yamanaka H,Hosoda Y,Sakuma K,Matuoka Y,Odaka M,Yamaguchi M,Yosida H,Morisawa H,Murayama T

    更新日期:2000-11-01 00:00:00

  • Cohort profile: the ages 2003 cohort study in Aichi, Japan.

    abstract:BACKGROUND:The longevity of Japanese is thought to be associated with psychosocial factors such as sense of coherence, social support, and social capital. However, the actual factors responsible and the extent of their contribution to individual health status are not known. METHODS:The Aichi Gerontological Evaluation ...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20100135

    authors: Nishi A,Kondo K,Hirai H,Kawachi I

    更新日期:2011-01-01 00:00:00

  • Comparison of Intentional and Unintentional Injuries Among Chinese Children and Adolescents.

    abstract:BACKGROUND:The patterns and risk factors of intentional injuries compared to unintentional injuries among Chinese children and adolescents have not been examined in depth. This work comprehensively describes patterns of intentional injuries in China, for which little information has been previously published. METHODS:...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20190152

    authors: Yin X,Li D,Zhu K,Liang X,Peng S,Tan A,Du Y

    更新日期:2020-12-05 00:00:00

  • Comparison of disease patterns and outcomes between non-Japanese and Japanese patients at a single tertiary emergency care center in Japan.

    abstract:BACKGROUND:Japan's historically low immigration rate and monolingual culture makes it a particularly interesting setting for clarifying non-national medical care. Our study objective was to examine disease patterns and outcome differences between Japanese and non-Japanese patients in a rapidly globalizing nation. METH...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20200211

    authors: Ishii E,Nawa N,Matsui H,Otomo Y,Fujiwara T

    更新日期:2020-12-05 00:00:00

  • Descriptive epidemiology of diabetes prevalence and HbA1c distributions based on a self-reported questionnaire and a health checkup in the JPHC diabetes study.

    abstract:BACKGROUND:The present study examined the prevalence of diabetes in Japan during the late 1990s and early 2000s using the Japan Public Health Center-based Prospective Diabetes cohort. We also investigated the distributions of HbA1c values in noncompliant diabetic participants in the cohort. METHODS:A total of 28 183 r...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20130196

    authors: Kabeya Y,Kato M,Isogawa A,Takahashi Y,Matsushita Y,Goto A,Iso H,Inoue M,Mizoue T,Tsugane S,Kadowaki T,Noda M

    更新日期:2014-01-01 00:00:00

  • Breast Cancer Incidence Trends and Projections in Northeastern Thailand.

    abstract:BACKGROUND:The northeast has the lowest incidence of breast cancer of all regions in Thailand, although national rates are increasing. The heterogeneity in subnational trends necessitates a comprehensive evaluation of breast cancer incidence trends and projections to provide evidence for future region-specific strategi...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20170045

    authors: Virani S,Chindaprasirt J,Wirasorn K,Sookprasert A,Somintara O,Vachirodom D,Koonmee S,Srinakarin J,Kamsa-Ard S,Suwanrungruang K,Rozek LS,Sriplung H,Wiangnon S

    更新日期:2018-07-05 00:00:00

  • Relationship between socioeconomic variables and obesity in Korean adolescents.

    abstract:BACKGROUND:Despite the importance of obesity and its association with socioeconomic status, little is known about this condition in Korean adolescents. We examined the relationship between obesity in Korean adolescents and several socioeconomic variables and compared the association of obesity with conventional and sub...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.je20100099

    authors: Oh IH,Cho Y,Park SY,Oh C,Choe BK,Choi JM,Yoon TY

    更新日期:2011-01-01 00:00:00

  • The impact of marital transitions on vegetable intake in middle-aged and older Japanese adults: a five-year longitudinal study.

    abstract:BACKGROUND:Marital transitions are associated with adverse health events, such as mortality and cardiovascular disease. Since marital transitions (e.g., becoming widowed) are unavoidable life events, it is necessary to identify modifiable intermediate outcomes. Thus, we examined the association between marital transiti...

    journal_title:Journal of epidemiology

    pub_type: 杂志文章

    doi:10.2188/jea.JE20200343

    authors: Noguchi T,Kondo F,Nishiyama T,Otani T,Nakagawa-Senda H,Watanabe M,Imaeda N,Goto C,Hosono A,Shibata K,Kamishima H,Nogimura A,Nagaya K,Yamada T,Suzuki S

    更新日期:2020-10-17 00:00:00