Granulocyte-colony stimulating factor treatment of chronic myocardial infarction.

abstract：PURPOSE:The PPAR-alpha agonists (fibrates) are commonly used in the treatment of dyslipidemia. It has been hypothesized that the cardio-protective effects of fibrates are partially due to immunomodulatory effects. However, there is a paucity of data regarding the effect of fibrates on neutrophilic chemokines such as ep...

journal_title：Cardiovascular drugs and therapy

authors： Price ET,Welder GJ,Zineh I

更新日期：2012-04-01 00:00:00

abstract：:The results of the European Working Party for Hypertension in the Elderly Study showed that treatment of high blood pressure reduced the morbidity and mortality from strokes and myocardial infarction and reduced the incidence of heart failure in elderly patients. The largest number of hypertensive patients are elderly...

journal_title：Cardiovascular drugs and therapy

authors： McCarthy ST,McCarthy GL,John SM,Gould SE

更新日期：1990-01-01 00:00:00

abstract：:Major advances have been established in the handling of hypertensive vascular disease in recent years. However, drug compliance, drug costs, and the side effects of antihypertensive agents have prompted the question of whether intermittent therapy or even possible removal of medication represents an alternative to lif...

journal_title：Cardiovascular drugs and therapy

authors： Schmieder RE,Rockstroh JK

更新日期：1990-12-01 00:00:00

abstract：:The cardiovascular effects and safety of transdermal nicotine patches were assessed in 50 healthy smokers using repeated 48 hour ambulatory electrocardiographic monitoring as a part of a smoking cessation program. Following baseline measurements, subjects were randomized to active (n = 25) or placebo (n = 25) treatmen...

journal_title：Cardiovascular drugs and therapy

authors： Khoury Z,Comans P,Keren A,Lerer T,Gavish A,Tzivoni D

更新日期：1996-05-01 00:00:00

abstract：:Thiazide diuretics are particularly efficacious in the treatment of hypertension in blacks. A number of observations suggest that many hypertensive blacks have features consistent with a status of "corrected" volume expansion. Our studies, as well as those of other investigators, show that the Na,K pump is inhibited i...

journal_title：Cardiovascular drugs and therapy

authors： Quintanilla AP,Wagener OE

更新日期：1990-03-01 00:00:00

abstract：:Recent surveys in the U.S. have reported, for the first time, that a significant number of patients with hypertension are finding that the cost of medication and treatment in general is an obstacle to treatment. The cost of management of hypertension can be contained if: a) the diagnostic workup is kept simple (this d...

journal_title：Cardiovascular drugs and therapy

authors： Moser M

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Many studies have demonstrated a gap between guidelines for the prevention of cardiovascular disease (CVD) and their implementation in clinical practice. AIM:The PEGASE education program has been devised with an aim to improve the management of patients at high risk of CVD. METHODS:In a multicentre study c...

journal_title：Cardiovascular drugs and therapy

authors： Bruckert E,Giral P,Paillard F,Ferrières J,Schlienger JL,Renucci JF,Abdennbi K,Durack I,Chadarevian R,PEGASE group.

更新日期：2008-12-01 00:00:00

abstract：:People who consume a diet rich in fruit and vegetables have lower risks of cancer, cardiovascular disease and all-cause mortality. Many prospective cohort studies have reported inverse associations between dietary intake or blood levels of beta-carotene and risks of cancer. Several large-scale trials were set up to as...

journal_title：Cardiovascular drugs and therapy

authors： Clarke R,Armitage J

更新日期：2002-09-01 00:00:00

abstract：:To further evaluate the significance of p38 MAPK as trigger or mediator in ischaemic preconditioning, anisomycin and SB 203580 were used to manipulate its activation status. Special attention was given to the concentration of the drugs and protocols used. The isolated perfused rat heart, subjected to either 25 min glo...

journal_title：Cardiovascular drugs and therapy

authors： Lochner A,Genade S,Hattingh S,Marais E,Huisamen B,Moolman JA

更新日期：2003-05-01 00:00:00

abstract：:Quality of life in heart failure patients is receiving increased attention as a reflection of a treatment's potential secondary benefit of general well-being and daily functioning. The Metoprolol in Dilated Cardiomyopathy (MDC) trial was conducted as a large, multicenter trial to establish the effects of metoprolol on...

journal_title：Cardiovascular drugs and therapy

authors： Wiklund I,Waagstein F,Swedberg K,Hjalmarsson A

更新日期：1996-07-01 00:00:00

abstract：:An 82-year old man was admitted with acute pulmonary edema. Myocardial ischemia and electrolyte abnormalities were excluded and he responded promptly to frusemide, nitrates and morphine. On admission, the duration of the QRS interval was markedly abnormal at 240 ms with a nonspecific intraventricular conduction defect...

journal_title：Cardiovascular drugs and therapy

authors： Kolettis TM,Naka KK,Katsouras C,Michalis LK,Bourantas K

更新日期：2003-07-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of death in men and women in the USA. Once a patient experiences an acute coronary syndrome (ACS), they are at increased risk for hospital readmission within 30 days and 6 months after discharge and more importantly, they have worse survival. Hospital readmissions lead to po...

journal_title：Cardiovascular drugs and therapy

authors： Paruchuri V,Gaztanaga J,Rambhujun V,Smith R,Farkouh ME

更新日期：2018-12-01 00:00:00

abstract：:Early reperfusion represents the key strategy in ST elevation myocardial infarction. However, reperfusion may induce myocardial damage due to the reperfusion myocardial injury, compromising the full potential of reperfusion therapy and accounting for unfavourable results in high risk patients. Adenosine seems to atten...

journal_title：Cardiovascular drugs and therapy

authors： Kassimis G,Davlouros P,Patel N,De Maria G,Kallistratos MS,Kharbanda RK,Manolis AJ,Alexopoulos D,Banning AP

更新日期：2015-01-01 00:00:00

abstract：:To assess the effect of antihypertensive drugs on aortic distensibility, we evaluated the aortic distensibility of 33 hypertensive patients before and after antihypertensive treatment by using cine magnetic resonance imaging. Thirty three hypertensive patients were divided into three groups and treated for 12 weeks wi...

journal_title：Cardiovascular drugs and therapy

authors： Honda T,Hamada M,Shigematsu Y,Matsumoto Y,Matsuoka H,Hiwada K

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:The prevalence and consequences of prediabetic dysglycemia and undiagnosed diabetes is unknown in patients with heart failure (HF) and preserved ejection fraction (HFpEF) and has not been compared to heart failure and reduced ejection fraction (HFrEF). METHODS:We examined the prevalence and outcomes associated...

journal_title：Cardiovascular drugs and therapy

authors： Kristensen SL,Jhund PS,Lee MMY,Køber L,Solomon SD,Granger CB,Yusuf S,Pfeffer MA,Swedberg K,McMurray JJV,CHARM Investigators and Committees.

更新日期：2017-12-01 00:00:00

abstract：:Glucose-insulin-therapy for acute myocardial infarction (AMI) has had a long history, going back 37 years to the pioneering concepts of Sodi-Pallares. Although a recent meta-analysis of a number of smaller trials has suggested mortality benefit, it is only the South American trial, published in Circulation in 1998, th...

journal_title：Cardiovascular drugs and therapy

authors： Apstein CS,Opie LH

更新日期：1999-05-01 00:00:00

abstract：:Unselective and beta 1-selective beta-blockers may induce vasoconstriction of normal and stenotic epicardial coronary arteries. To analyze the influence of the "vasodilatory" beta-blocker celiprolol on coronary vasomotility, 0.4 mg celiprolol/kg were intravenously infused over 4 minutes in 13 patients with coronary ar...

journal_title：Cardiovascular drugs and therapy

authors： Jost S,Hausmann D,Lippolt P,Sturm M

更新日期：1997-04-01 00:00:00

abstract：:Tracer techniques have provided new insight in cardiology by allowing noninvasive studies of myocardial perfusion, function, metabolism, and, more recently, ligand-receptor interaction. Positron emission tomography allows accurate quantification and the use of natural substrates labelled with 11C, 13N, or 15O. Myocard...

journal_title：Cardiovascular drugs and therapy

authors： Rigo P,de Landsheere C,Melon P,Kulbertus H

更新日期：1990-08-01 00:00:00

abstract：:Excess activity of the sympathetic nervous system (SNS) is linked to human obese hypertension and to salt-sensitive hypertension. Paradoxically, reduced SNS activity has been implicated as a contributor to obesity, particularly in animal models, and salt loading usually inhibits SNS activity. We have investigated the ...

journal_title：Cardiovascular drugs and therapy

authors： Ernsberger P,Koletsky RJ,Collins LA,Bedol D

更新日期：1996-06-01 00:00:00

abstract：PURPOSE:Mechanical stretch is an arrhythmogenic factor found in situations of cardiac overload or dyssynchronic contraction. Ranolazine is an antianginal agent that inhibits the late Na (+) current and has been shown to exert a protective effect against arrhythmias. The present study aims to determine whether ranolazin...

journal_title：Cardiovascular drugs and therapy

authors： Chorro FJ,del Canto I,Brines L,Such-Miquel L,Calvo C,Soler C,Parra G,Zarzoso M,Trapero I,Tormos Á,Alberola A,Such L

更新日期：2015-06-01 00:00:00

abstract：:Chronic renal failure (CRF) patients with a stable course were asked to participate in a follow-up program in which they were randomized into two groups: 1) the placebo group taking their standard antihypertensive therapy without any calcium ion blocker: and 2) the nisoldipine group, those patients taking the calcium ...

journal_title：Cardiovascular drugs and therapy

authors： Eliahou HE,Cohen D,Ben-David A,Herzog D,Serban I,Gavendo S,Kapuler S,Kogan N,Hellberg B

更新日期：1988-01-01 00:00:00

abstract：:The use of calcium antagonists and diuretics in combination for treatment of hypertension is controversial. In a single-blind study 16 patients (8 men, 8 women, age range 39 to 62 years) with primary hypertension of mild to moderate degree were given slow-release nifedipine 20 mg twice daily for 6 weeks, thereafter ei...

journal_title：Cardiovascular drugs and therapy

authors： Ferrara LA,Marotta T,Pasanisi F,Mastranzo P,Mancini M

更新日期：1988-03-01 00:00:00

abstract：:Though the exact physiology and pathology of lipoprotein(a) [Lp(a)] remains unknown, it has been demonstrated that increased serum Lp(a) levels are correlated with an increased risk of atherosclerotic vascular disease. The effects of lipid-lowering drugs on Lp(a) levels is unclear because of inconsistencies between st...

journal_title：Cardiovascular drugs and therapy

authors： Dobs AS,Prasad M,Goldberg A,Guccione M,Hoover DR

更新日期：1995-10-01 00:00:00

abstract：:Patients with mild to moderate hypertension (diastolic blood pressure > or = 95 and < or = 115 mmHg) and renal dysfunction entered one of two studies to assess the safety of efficacious daily doses of quinapril on renal function and blood pressure. Twenty-four patients with moderate renal impairment (MRI) (creatinine ...

journal_title：Cardiovascular drugs and therapy

authors： Miller MA,Texter M,Gmerek A,Robbins J,Shurzinske L,Canter D

更新日期：1994-04-01 00:00:00

abstract：:Despite continuous advances in myocardial revascularization procedures and intracoronary devices, patients with ischemic heart disease (IHD) still experience worse prognosis and poor quality of life (QoL). Indeed, chronic stable angina (CSA) is a common disease with a large burden on healthcare costs. Traditionally, C...

journal_title：Cardiovascular drugs and therapy

authors： Guarini G,Huqi A,Morrone D,Marzilli M

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Although erythropoietin (EPO) is known to express angiogenic and cardioprotective effects, it also induces hypertension, polycythemia, and platelet activation, which may cause serious adverse effects in patients with cardiovascular diseases. We compared the angiogenic effects of EPO and its nonerythropoietic de...

journal_title：Cardiovascular drugs and therapy

authors： Yanagawa T,Toba K,Kato K,Suzuki T,Minagawa S,Saigawa T,Ozawa T,Oda M,Takayama T,Hanawa H,Higuchi M,Saito H,Aizawa Y

更新日期：2013-04-01 00:00:00

abstract：:The place of digoxin in the pediatric cardiologist's armamentarium remains uncertain. As an antiarrhythmic, its use in the Wolff-Parkinson-White syndrome is obsolete, but it remains useful in the treatment of the chronic atrial fibrillation seen in some patients postoperatively and in children with dilated cardiomyopa...

journal_title：Cardiovascular drugs and therapy

authors： Redington AN,Carvalho JS,Shinebourne EA

更新日期：1989-03-01 00:00:00

abstract：:Milrinone is shown in 10 patients to be a valuable pharmacological bridge to heart transplantation; it can stabilize and improve decompensated chronic heart failure (CHF) in cases where the response to beta-agonists is inadequate. One patient who had suffered an acute myocardial infarction with heart failure resistant...

journal_title：Cardiovascular drugs and therapy

authors： Sherry KM,Locke TJ

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVES:To evaluate and compare the functional type and the degree of antagonism of the selective angiotensin II type 1 receptor blockers (ARB) losartan, EXP 3174 (the active metabolite of losartan), valsartan and candesartan in human internal mammary arteries. METHODS:Human internal mammary arteries were obtained ...

journal_title：Cardiovascular drugs and therapy

authors： Wagenaar LJ,Voors AA,Buikema H,van Buiten A,Lübeck RH,Boonstra PW,van Veldhuisen DJ,van Gilst WH

更新日期：2002-07-01 00:00:00

abstract：:Suppression of formation of angiotensin II (A-II) is thought to be a major contributor to the hemodynamic response to angiotensin-converting enzyme inhibition (ACE-in) therapy. However, angiotensin II (A-II) plasma levels may rebound during ACE-in treatment. The study sought to verify the feasibility, safety, and tole...

journal_title：Cardiovascular drugs and therapy

authors： Di Pasquale P,Bucca V,Scalzo S,Paterna S

更新日期：1998-05-01 00:00:00