Abstract:
:A 21-year-old man presented with hypertrophic nail dystrophy and subungual debris of all 20 nails, hyperkeratotic plaques on the heels of both feet, and oral leukokeratosis. He had an extensive family history of similar clinical findings. The patient's clinical presentation and history were consistent with pachyonychia congenita (PC), an autosomal dominant genodermatosis caused by mutations in the genes for keratin 6, K6a and K6b; keratin 16, K16; and keratin 17, K17.
journal_name
Cutisjournal_title
Cutisauthors
Kohli Nsubject
Has Abstractpub_date
2009-11-01 00:00:00pages
269-71issue
5eissn
0011-4162issn
2326-6929journal_volume
84pub_type
杂志文章相关文献
CUTIS文献大全abstract::Panniculitis occurred in a 34-year-old man. The clinical features of the panniculitis were not consistent with erythema nodosum, Weber-Christian disease, or the other previously described panniculitides. Subsequent investigation showed concurrent hepatitis possibly caused by type A hepatitis virus. The skin lesions re...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract::A case of perianal condylomata lata, one of a variety of skin lesions manifested in secondary syphilis, is presented. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract::Eosinophilic pustular folliculitis (EPF) has been described mostly in adults from Japan. From the few reports of children with EPF it is clear that the disease displays the characteristic features, with some clinical differences compared to EPF in adults. We describe the case of an 8-year-old boy with multiple vesicle...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:1996-08-01 00:00:00
abstract::A case of coexistent bullous pemphigoid and systemic lupus erythematosus is reported. Evidence for an immunologic pathogenesis is reviewed for both disorders. It is suggested that the coexistence of bullous pemphigoid and systemic lupus erythematosus may represent a similar pathomechanism. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1978-03-01 00:00:00
abstract::Pruritus can be due to a variety of factors and can often be difficult for a physician to manage. Often the etiology is psychosomatic, wherein a careful history is the key to proper diagnosis. Such a case is presented. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract::Skin cancer is the most common form of cancer in the United States, with more than 1 million cases of nonmelanoma skin cancer diagnosed annually and an estimated 53,600 cases of melanoma and 7400 deaths expected during the year 2002. Excess exposure to UV radiation has long been linked to both melanoma and nonmelanoma...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::Lichen spinulosus is a benign follicular eruption seen primarily in younger persons and is frequently classified among the follicular keratoses. Grouped patches of spinous papules are seen involving the elbows, knees, and buttocks. An atopic background is frequently present in these patients. We describe here a patien...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract::Cutaneous angiosarcoma is a rare aggressive malignancy of vascular origin that usually arises in the scalp or face of elderly men. We describe a case of primary cutaneous angiosarcoma with skin metastases and presumed metastases to the lung in a 58-year-old man who presented with persistent bloody pleural effusions, a...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2012-03-01 00:00:00
abstract::A 71-year-old woman presented with pink to violaceous, flat-topped, polygonal papules on the volar wrists, extensor elbows, and bilateral lower legs of 3 years' duration. She also had erythematous, violaceous, infiltrated plaques with microvesiculation on the bilateral thighs of several months' duration. She reported ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2017-12-01 00:00:00
abstract::Long-term exposure to arsenic has been linked to the development of numerous cutaneous neoplasms including arsenical keratoses, basal cell carcinomas (BCCs), and squamous cell carcinomas (SCCs). We report a patient with a remote history of psoriasis treated with arsenic who subsequently developed more than 40 nonmelan...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2010-04-01 00:00:00
abstract::A typical case of eosinophilic ulcer of the tongue is described. It confirms the traumatic cause for this benign, self-healing lesion that may be misdiagnosed and clinically confused with squamous cell carcinoma. The short time that the lesion takes to heal is an important diagnostic clue in differentiating eosinophil...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::Pyoderma gangrenosum (PG) and hidradenitis suppurativa (HS) are rare chronic inflammatory dermatoses of unknown etiologies that often are refractory to conventional treatments. The therapeutic benefits of tumor necrosis factor a (TNF-α) inhibitors have been reported in patients with refractory PG or HS. The copresenta...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2015-06-01 00:00:00
abstract::Nevus sebaceus (NS) is a congenital skin lesion arising on the face and scalp that has been linked to the development of various carcinomas. We describe a case of microcystic adnexal carcinoma (MAC) arising in an NS on the scalp of a 62-year-old man. Excisional skin biopsy and hematoxylin and eosin stains were perform...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2007-10-01 00:00:00
abstract::Leukonychia striata of a unique appearance and distribution is described in a 51-year-old woman. Histopathologic examination of a specimen from the nail plate revealed a transverse band of parakeratosis on the ventral surface. Disturbance in keratinization on the nail plate is presumed to be secondary to abnormalities...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::Introduced in 2008 and subsequently popularized in South Korea, cosmetic eye whitening has been offered as a treatment of chronic conjunctival hyperemia. Patients undergo conjunctivectomy with topical mitomycin C (MMC) 0.02% application to achieve a whitened appearance from bleaching of avascular sclera. Much speculat...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2017-09-01 00:00:00
abstract::Widespread dermatitis developed in three women after use of vaginal preparations. Besides allergic contact dermatitis, these cases involved erythema multiforme and a photosensitive eruption. Antigen absorption into the general circulation through the vaginal wall, and its deposition at distant skin sites, appeared to ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract::Investigators conducted two double-blind, randomized, parallel-group trials to compare the efficacy of fluticasone propionate cream, 0.05%, and betamethasone valerate cream, 0.1%, in the treatment of moderate-to-severe psoriasis. Up to 100 gm/week of the study medication was applied topically to affected areas of the ...
journal_title:Cutis
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-02-01 00:00:00
abstract::Bacterial resistance to antibiotics began to emerge soon after their introduction. Beginning in the 1970s, Propionibacterium acnes also began to show decreased sensitivity to the antibiotics typically used in acne management. Clinically, this trend has translated to decreased efficacy and even nonresponse to therapy. ...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2007-07-01 00:00:00
abstract::Twenty healthy subjects (7 men and 13 women) with average baseline P. acnes counts equal to or greater than 1.0 x 10(5) were treated twice a day for eleven days in a randomized, double-blind study with either erythromycin 1.5 percent topical solution or clindamycin phosphate 1.0 percent topical solution. P. acnes coun...
journal_title:Cutis
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1983-03-01 00:00:00
abstract::Scurvy is a well-known disease of vitamin C deficiency that still occurs in industrialized countries. The clinical manifestations of follicular hyperkeratosis, perifollicular petechiae, corkscrew hairs, and easy bruising are due to defective collagen synthesis and can be mistaken for small vessel vasculitis. Populatio...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2010-10-01 00:00:00
abstract::An association between pemphigus erythematosus and systemic lupus erythematosus is well recognized. However, most reports strongly imply that the clinical manifestations of lupus erythematosus are usually minimal or only serologically significant. We describe the case of a 27-year-old black woman who experienced life-...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1986-09-01 00:00:00
abstract::Seborrheic dermatitis is a chronic recurrent inflammatory skin condition that mainly affects areas containing sebaceous glands. I present a case of a novel effective topical nonsteroidal treatment (pimecrolimus 1.0% cream) for facial seborrheic dermatitis. Pimecrolimus is a member of a new class of nonsteroidal agents...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract::A 63-year-old man with recurrent metastatic malignant melanoma presented with a painful right twelfth thoracic dermatomal eruption initially thought to be herpes zoster. However, 3 weeks later, the patient clearly had melanoma skin metastases confined exclusively to this dermatome. Radiotherapy and opiate analgesics p...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::Porokeratosis is a rare keratinization disorder of the skin characterized by annular plaques with an atrophic center surrounded by a raised keratotic wall that spreads centrifugally. We report a case of porokeratosis of Mibelli with mutilation. A 30-year-old woman presented with atrophic plaques on the index fingers o...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2010-08-01 00:00:00
abstract::Alefacept is the first biologic agent approved by the US Food and Drug Administration for moderate to severe chronic plaque psoriasis. Prior clinical studies excluded patients with palmoplantar psoriasis or erythroderma. We report 2 patients with recalcitrant psoriasis who responded completely to a full course of alef...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::Psoriatic nail involvement is common and accompanies skin lesions on the body surface. The occurrence of nail psoriasis has been reported in up to 50 percent of patients, including children, adults, and the elderly. The characteristics of psoriatic nails are pitting, discoloration, onycholysis, subungual hyperkeratosi...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::Vitiligo vulgaris is an autoimmune pigmentary disorder with no universally efficacious therapeutic options. Separate applications of calcipotriene ointment 0.005% and topical corticosteroid ointments have been successful in the repigmentation of vitiligo. We sought to examine the efficacy of a combination calcipotrien...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract::Toxic epidermal necrolysis (TEN) is a rare but life-threatening disorder of children and adults in which the skin peels off in sheets and mucosal surfaces slough. It is best viewed as a severe from of erythema multiforme, with even more extreme involvement than one sees with the Stevens-Johnson syndrome (SJS). However...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::Four cases of rare familial multiple eccrine spiradenomas showing features of dermal cylindromas and associated with epithelioma adenoides cysticum of Brooke are reported. Skin biopsy specimens were obtained from three generations of this family and routine histochemical and immunoperoxidase stains were used. The elde...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::Topical imiquimod 5% cream is approved for the treatment of actinic keratosis (AK), superficial basal cell carcinoma, and external genital warts. The drug's mechanism of action is via stimulation of innate and acquired immune responses, which ultimately leads to inflammatory cell infiltration within the field of drug ...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2005-10-01 00:00:00