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Circulating procoagulant microparticles in acute pulmonary embolism: a case-control study.

Abstract：

:We investigated whether circulating procoagulant microparticles (CPMPs) contributed to hypercoagulability in 45 patients with acute pulmonary embolism (APE) and in 45 controls with and 45 controls without cardiovascular risk factors. Concentrations of CPMPs and platelet-derived microparticles (PMPs) were statistically significantly higher in patients with APE than in controls without cardiovascular risk factors. PMPs appeared to be the main source of procoagulant microparticle release in APE, but this correlation disappeared when APE patients were compared to controls with cardiovascular risk factors. CPMPs may have a role in venous thrombosis as mediators of cardiovascular risk factors.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Bal L,Ederhy S,Di Angelantonio E,Toti F,Zobairi F,Dufaitre G,Meuleman C,Mallat Z,Boccara F,Tedgui A,Freyssinet JM,Cohen A

doi

10.1016/j.ijcard.2009.11.048

subject

Has Abstract

pub_date

2010-11-19 00:00:00

pages

321-322

issue

2

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(09)01645-3

journal_volume

145

pub_type

信件

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