Six-year experience: long-term disease control outcomes for partial breast irradiation using MammoSite balloon brachytherapy.

Abstract:

BACKGROUND:This report describes estimated 4-year tumor bed and ipsilateral breast recurrence-free intervals, event-free survival, disease-specific survival, and overall survival in a cohort of MammoSite brachytherapy (MBT) patients with mature follow-up treated at a single institution over a 6-year period. METHODS AND MATERIALS:An analysis of MBT cases was performed by using a prospectively collected quality-assurance database, departmental chart review, and electronic medical records. Patient-, tumor-, treatment-, and outcome-specific data were extracted and recorded into a research database. Patients were eligible for inclusion in this analysis if they were at least 6 months post-MBT. RESULTS:From May 2002 through March 2008, 111 MBT patients have been treated and were eligible for the present analysis. With a median follow-up of 46 months, the estimated 4-year outcomes for the entire cohort were tumor bed control 99%, ipsilateral breast control 95%, event-free survival 88%, disease-specific survival 97%, and overall survival 92%. CONCLUSIONS:The present study shows low rates of local and ipsilateral breast disease failure in a well-defined cohort of MBT patients with mature follow-up.

journal_name

Am J Surg

authors

Harper JL,Watkins JM,Zauls AJ,Wahlquist AE,Garrett-Mayer E,Baker MK,Cole DJ,Dragun AE,Jenrette JM 3rd

doi

10.1016/j.amjsurg.2009.03.005

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

204-9

issue

2

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(09)00236-0

journal_volume

199

pub_type

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