Effect of recombinant human growth hormone on random pattern flaps in rats.

Abstract:

:Recombinant human growth hormone, a very potent anabolic hormone, plays a significant role in growth regulation, bone metabolism, and wound healing. This study evaluates its effect on random flap survival. Rats were randomly divided into 2 groups. A dorsal random flap, cephalically based, was used. One group received 5 mg/kg subcutaneous injection of recombinant human growth hormone 1 hour before surgery and a repeat dosage every 24 hours for 1 week. The others served as controls. At the end of 1 week, average weight and flap survival was evaluated. There was no difference in flap survival between the groups. Treated rats had gained significantly more weight. Recombinant human growth hormone had no beneficial effect on flap survival. The lack of a deleterious effect of the hormone on random flap survival and its significant effect on rat weight and well being supports its safe use during flap surgery.

journal_name

Ann Plast Surg

authors

Shalom A,Hollander L,Westreich M

doi

10.1097/SAP.0b013e318193498c

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

556-7

issue

5

eissn

0148-7043

issn

1536-3708

journal_volume

63

pub_type

杂志文章
  • Prevention of Lymphedematous Change in the Mouse Hindlimb by Nonvascularized Lymph Node Transplantation.

    abstract::Lymphedema is a condition characterized by progressive swelling and adipose deposition that occurs commonly after lymphadenectomy. Recent clinical studies have suggested that the transfer of lymph nodes to the lymphedematous limb can improve lymphatic function. In this report, we investigate dynamic modulation of lymp...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000000428

    authors: Shioya R,Furukawa H,Murao N,Hayashi T,Oyama A,Funayama E,Yamamoto Y,Saito N

    更新日期:2016-04-01 00:00:00

  • A new method for the primary repair of unilateral cleft lip.

    abstract::The author reports primary repair of complete unilateral cleft lip using three flaps: (1) a small triangular flap at the vermilion border; (2) a large triangular flap at the upper lip; and (3) an alar flap. This method has the advantages that the design can be made by any beginner in plastic surgery, reconstruction of...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-198006000-00012

    authors: Onizuka T

    更新日期:1980-06-01 00:00:00

  • Outcome and management of infected wounds after total hip arthroplasty.

    abstract::Infected wounds after total hip arthroplasty can be limb threatening. Management strategies are designed to eradicate infection, to obtain stable wound coverage, and to preserve the prosthesis. However, there is no general consensus for optimal management. The authors reviewed their 7-year combined orthopaedic and pla...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200212000-00006

    authors: Gusenoff JA,Hungerford DS,Orlando JC,Nahabedian MY

    更新日期:2002-12-01 00:00:00

  • Use of tissue expanders with external ports.

    abstract::The high number of reconstructive dilemmas brought about by more aggressive treatment of congenital malformations and burns has created the need for large quantities of donor skin for local coverage. Tissue expansion with external ports has become part of the authors' surgical armamentarium. From January 1996 to Novem...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200044010-00003

    authors: Lozano S,Drucker M

    更新日期:2000-01-01 00:00:00

  • Repair of chronic mallet finger deformity using Mitek micro arc bone anchor.

    abstract::Surgical correction of chronic mallet finger caused by terminal tendon disruption was carried out in 22 patients. The distal stump of the tendon was fixed to the base of the distal phalanx with a Mitek micro arc bone anchor. In all patients the mallet finger deformity was corrected. There were 15 patients with excelle...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000151464.03967.a2

    authors: Ulkür E,Açikel C,Ergun O,Celiköz B

    更新日期:2005-04-01 00:00:00

  • An anatomical study of the facial artery.

    abstract::The anatomical variations encountered in the dissection of 50 facial arteries in 25 adult preserved cadavers are presented. The facial artery was symmetrical in 17 of 25 (68%) of the dissections. The facial artery terminated as an angular facial artery in 34 (68%), a lateral nasal vessel in 13 (26%), and a superior la...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-198807000-00003

    authors: Niranjan NS

    更新日期:1988-07-01 00:00:00

  • Long-term survival in basal cell carcinoma metastatic to bone: a case report.

    abstract::A total of 97 cases of metastatic basal cell carcinoma have been reported in the literature, 22 of which were metastatic to bone. To date there has been no survival following bone metastasis. A case report of significant long-term survival--over three times the expected--is presented. The treatment described is perhap...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-197912000-00010

    authors: Briggs RM,Pestana I

    更新日期:1979-12-01 00:00:00

  • The effect of angiotensin (1-7) on survival of random pattern skin flaps with nicotine-induced ischemia in rats.

    abstract:OBJECTIVE:The purpose of this study was to reveal the effect of angiotensin (1-7) on survival of random pattern, nicotinized, ischemic flap model in rats. MATERIALS AND METHODS:We used female Sprague Dawley rats weighing between 250 and 300 g. The study was performed on 3 groups each of them was consisted of 30 rats (...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e3182069bfd

    authors: Baykan H,Günay GK,Ozyazgan I,Soyuer I

    更新日期:2012-01-01 00:00:00

  • Controlled clinical trial with pirfenidone in the treatment of breast capsular contracture: association of TGF-β polymorphisms.

    abstract:BACKGROUND:Breast capsular contracture (BCC) is a commonly adverse event postmammoplastly characterized by an immune response mediated by cytokines and transforming growth factor (TGF)-β1 resulting in excessive synthesis and deposit of extracellular matrix around the breast implant. Presence of TGF-β1 polymorphisms has...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e31822284f4

    authors: Veras-Castillo ER,Cardenas-Camarena L,Lyra-Gonzalez I,Muñoz-Valle JF,Lucano-Landeros S,Guerrerosantos J,Gonzalez-Ulloa B,Mercado-Barajas JL,Sanchez-Parada MG,Azabache-Wennceslao R,Armendariz-Borunda J

    更新日期:2013-01-01 00:00:00

  • Avoiding free nipple grafting with the inferior pedicle technique.

    abstract::In cases of severe macromastia, the free nipple graft technique has been the traditional alternative to pedicle transposition. Distress over nipple survival in large reduction mammaplasty and long pedicle transposition is largely responsible for this.A retrospective investigation of the records of 142 reduction mammap...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000174363.04135.b9

    authors: Gerzenshtein J,Oswald T,McCluskey P,Caplan J,Angel MF

    更新日期:2005-09-01 00:00:00

  • Propranolol Therapy for Problematic Infantile Hemangioma.

    abstract:BACKGROUND:Infantile hemangioma (IH) is a common, benign tumor occurring in up to 10% of white infants. Propranolol has emerged as a front-line therapy for IH. The retrospective study examined the response of propranolol therapy on hemangioma size. METHODS:Twenty-seven children (4 to 20 weeks old) with IH were enrolle...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000000521

    authors: Ng M,Knuth C,Weisbrod C,Murthy A

    更新日期:2016-03-01 00:00:00

  • Double breast contour in primary aesthetic breast augmentation: incidence, prevention and treatment.

    abstract::The goal of this study was to define the incidence of double breast contour in primary aesthetic breast augmentation and to analyze its risk factors. An independent plastic surgeon analyzed the data of 200 patients who had a primary aesthetic breast augmentation with silicone gel implant and with a minimum 12-month fo...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e3181b14284

    authors: Médard de Chardon V,Balaguer T,Chignon-Sicard B,Lebreton E

    更新日期:2010-04-01 00:00:00

  • Pulmonary Function After Pedicled Transverse Rectus Abdominis Musculocutaneous Flap Breast Reconstruction.

    abstract::Tight abdominal closures, as can be seen during transverse rectus abdominis musculocutaneous (TRAM) flap breast reconstruction, have been shown to increase intra-abdominal pressure, thereby decreasing thoracopulmonary compliance and increasing the workload of breathing. The purpose of this article was to quantitate pu...

    journal_title:Annals of plastic surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/SAP.0000000000000310

    authors: Shultz KJ,Don S,Mahabir RC,Verheyden CN

    更新日期:2016-01-01 00:00:00

  • Intercostal artery-based rectus abdominis transposition flap for sternal wound reconstruction: fifteen-year experience and literature review.

    abstract::The rectus abdominis transposition (RAT) flap is a well-accepted alternative to pectoralis muscle flaps for sternal reconstruction after debridement in poststernotomy mediastinitis. Use of this flap based on an intercostal artery pedicle, after division of the ipsilateral internal mammary artery (IMA), is a less-recog...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章,评审

    doi:10.1097/SAP.0b013e318070c6fb

    authors: Jacobs B,Ghersi MM

    更新日期:2008-04-01 00:00:00

  • Familial multiple glomus tumors: report of a pedigree and literature review.

    abstract::Glomus tumors are uncommon, benign soft tissue tumors that can occur in a familial or sporadic pattern. Only 15 pedigrees have been reported to date. We report a family with three generations developing multiple glomus tumors of the skin. Although controversy exists over pattern of inheritance, review of the published...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199401000-00013

    authors: Tran LP,Velanovich V,Kaufmann CR

    更新日期:1994-01-01 00:00:00

  • Freestyle Perforator Puzzle Flap for Posterior Trunk Reconstruction.

    abstract:BACKGROUND:Closure of extensive defects of posterior trunk can be challenging for reconstructive surgeons owing to the need of a large bulk of well-vascularized tissue to resurface the skin and the exposed hardware and to fill the dead spaces. We hypothesized that elevating multiple perforators flaps in various pattern...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000002259

    authors: Maruccia M,Di Taranto G,Schonauer F,DʼAndrea F,Losco L,Ribuffo D,Chen HC,Cigna E

    更新日期:2020-07-01 00:00:00

  • A Human-Derived, Collagen-Rich Hydrogel Augments Wound Healing in a Diabetic Animal Model.

    abstract:BACKGROUND:Application of collagen products to wounds has been shown to improve wound healing. Using a collagen-based hydrogel (cHG) capable of cellular support previously developed by our laboratory, we hypothesize that our hydrogel will increase the speed of wound healing by providing a 3-dimensional framework for ce...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000002380

    authors: Williams T,Sotelo Leon D,Kaizawa Y,Wang Z,Leyden J,Chang J,Fox PM

    更新日期:2020-09-01 00:00:00

  • Plastic Surgery Management of Victims of Terrorist Violence in Ankara, Turkey.

    abstract::Terror attacks have been progressively increasing worldwide through the present era. The management of the consequences of terrorism events is under debate in almost every scientific area. The organization and advancement of health services constitute important components of the crisis management. Similar to other spe...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000001238

    authors: İğde M,Kaplan A

    更新日期:2017-12-01 00:00:00

  • The "shutter flap" for large defects of the forehead.

    abstract::Acquired defects involving exposed bone in the central forehead can be challenging to reconstruct. We present a simple technique in which two superiorly based flaps of galea frontalis and skin are transposed medially, like the shutter of a camera. Full-thickness grafts are used to close the donor site. This is a remar...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199604000-00019

    authors: Levine NS,Sahl WJ,Stewart JB

    更新日期:1996-04-01 00:00:00

  • Central Pedicle Reduction in Gigantomastia Without Free Nipple Graft.

    abstract:BACKGROUND:Various pedicle techniques have been described in breast reduction surgery. However, in cases of massive hypertrophy, the free nipple graft technique is still being performed by some surgeons out of fear of losing the nipple-areolar complex (NAC). As such, we evaluated patients with severe gigantomastia who ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000000388

    authors: Karacor-Altuntas Z,Dadaci M,Ince B,Karamese M,Savaci N

    更新日期:2016-04-01 00:00:00

  • Combined laparoscopically harvested omental flap with meshed skin grafts and vacuum-assisted closure for reconstruction of complex chest wall defects.

    abstract:BACKGROUND:Chest wall reconstruction after radiation damage is a challenge in oncologic and plastic surgery. The defect can be reconstructed with laparoscopically harvested omental flap and meshed skin grafts. Our aim was to evaluate the use of vacuum-assisted closure (V.A.C.) in combination with laparoscopically harve...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/01.sap.0000237644.29878.0f

    authors: Ferron G,Garrido I,Martel P,Gesson-Paute A,Classe JM,Letourneur B,Querleu D

    更新日期:2007-02-01 00:00:00

  • Vascularized Partial Free Toe Tissue Transfer Under Local Anesthesia.

    abstract:BACKGROUND:This study was designed to introduce free toe soft tissue transfer using local infiltration anesthesia in patients not suitable for general anesthesia and local tissue coverage. METHODS:From January 2006 to August 2012, a total of 11 traumatic fingertip defects were reconstructed by toe soft tissue transfer...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000000163

    authors: Kim HS,Jeong TW,Park SH,Lee BI

    更新日期:2015-11-01 00:00:00

  • Factitious disorders: potential litigation risks for plastic surgeons.

    abstract::Patients with factitious physical disorders can present with a myriad of signs and symptoms. Common presentations include persistent wounds and abscesses that are often treated by plastic surgeons. Because these individuals are surreptitiously trying to maintain their illness, rather than recover, adverse outcomes are...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e318049cc41

    authors: Eisendrath SJ,Telischak KS

    更新日期:2008-01-01 00:00:00

  • Crossover innervation after digital nerve injury: myth or reality?

    abstract::Several clinical studies promulgate the concept that some degree of crossover innervation occurs after digital nerve injuries are sustained and that the intact digital nerve might even substitute for the loss of nerve function on the injured side. Other studies strongly dispute the existence of this phenomenon. An exc...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-200045050-00007

    authors: Weinzweig N

    更新日期:2000-11-01 00:00:00

  • Free latissimus dorsi muscle-chimeric thoracodorsal artery perforator flaps for reconstruction of complicated defects: does muscle still have a place in the domain of perforator flaps?

    abstract:PURPOSE:The reconstruction of complicated defects with 3-dimensional deficits remains challenging. The reconstruction of these defects requires not only coverage of surface but also appropriate obliteration of dead space, and muscle-chimeric perforator flaps can be a valuable option. Here, we present our experience wit...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e3182a6363c

    authors: Lee KT,Wiraatmadja ES,Mun GH

    更新日期:2015-05-01 00:00:00

  • Static syndrome after cross-facial nerve transplantation.

    abstract::A cross-facial nerve graft connected to buccal branches of the healthy facial nerve may carry axons destined for the orbicularis oris muscle as well as axons destined for elevators and abductors of the corner of the mouth. If this nerve graft innervates a pedicled or free muscle flap, contractions of the flap or part ...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-198710000-00009

    authors: Nicolai JP,Robinson PH

    更新日期:1987-10-01 00:00:00

  • Acquired digital fibrokeratoma: a case report.

    abstract::Acquired digital fibrokeratomas are benign, rare tumors that develop most commonly on the fingers. They can have an appearance of a rudimentary supernumerary digit or be misdiagnosed as a more common condition, such as verruca vulgaris. There are no case reports described in the plastic surgery literature. We are repo...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0b013e3182996ee6

    authors: Yu D,Morgan RF

    更新日期:2015-03-01 00:00:00

  • Computed tomography versus standard radiography in the assessment of fractures of the mandible.

    abstract::Twenty-nine fractures of the mandible were studied by standard radiographs and axial computed tomographic scans (hard copy). Independent reviewers analyzed each study in a blinded, non-paired fashion. When radiographic diagnostic sensitivities were compared on the basis of known surgical findings, the plain films were...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/00000637-199208000-00002

    authors: Creasman CN,Markowitz BL,Kawamoto HK Jr,Cohen S,Kioumehr F,Hanafee WN,Shaw WW

    更新日期:1992-08-01 00:00:00

  • Adjustable Fat Repositioning With Intraoral Anchoring: A New Technique in Transconjunctival Blepharoplasty.

    abstract:BACKGROUND:Prominent tear trough deformity and midfacial depression are the first priority in periorbital rejuvenation. To achieve harmonious lower eyelid improvement, we developed a novel approach to reposition infraorbital fat using intraoral anchoring in transconjunctival lower eyelid blepharoplasty. METHODS:Fourte...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章

    doi:10.1097/SAP.0000000000002089

    authors: Gao W,Qiao C,Lin X

    更新日期:2019-10-01 00:00:00

  • Mycobacterium tuberculosis infection of the hand: a case report and review of the literature.

    abstract::Despite the recent overall increase in cases of tuberculosis and other types of mycobacterial infection, the incidence of tuberculous hand infections remains extremely low in the United States. The rarity of this infection often results in delay in diagnosis and treatment. A case of Mycobacterium tuberculosis infectio...

    journal_title:Annals of plastic surgery

    pub_type: 杂志文章,评审

    doi:10.1097/00000637-199801000-00014

    authors: Karanas YL,Yim KK

    更新日期:1998-01-01 00:00:00