Abstract:
:Lesion and neuroimaging studies suggest that orbito-frontal cortex (OFC) supports temporal aspects of episodic memory. However, it is unclear whether OFC contributes to the encoding and/or retrieval of temporal context and whether it is selective for temporal relative to nontemporal (spatial) context memory. We addressed this issue with two complimentary studies: functional magnetic resonance imaging to measure OFC activity associated with successful temporal and spatial context memory during encoding and retrieval in healthy young participants, and a neuropsychological investigation to measure changes in spatial and temporal context memory in OFC lesion patients. Imaging results revealed that OFC contributed to encoding and retrieval of associations between objects and their temporal but not their spatial contexts. Consistent with this, OFC patients exhibited impairments in temporal but not spatial source memory accuracy. These results suggest that OFC plays a critical role in the formation and subsequent retrieval of temporal context.
journal_name
J Cogn Neuroscijournal_title
Journal of cognitive neuroscienceauthors
Duarte A,Henson RN,Knight RT,Emery T,Graham KSdoi
10.1162/jocn.2009.21316subject
Has Abstractpub_date
2010-08-01 00:00:00pages
1819-31issue
8eissn
0898-929Xissn
1530-8898journal_volume
22pub_type
杂志文章abstract::Theta (2-8 Hz), alpha (8-12 Hz), beta (12-35 Hz), and gamma (>35 Hz) rhythms are ubiquitous in the cortex. However, there is little understanding of whether they have similar properties and functions in different cortical areas because they have rarely been compared across them. We record neuronal spikes and local fie...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01600
更新日期:2020-10-01 00:00:00
abstract::The flexible allocation of attention enables us to perceive and behave successfully despite irrelevant distractors. How do acoustic challenges influence this allocation of attention, and to what extent is this ability preserved in normally aging listeners? Younger and healthy older participants performed a masked audi...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00761
更新日期:2015-05-01 00:00:00
abstract::Free recall is a fundamental paradigm for studying memory retrieval in the context of minimal cue support. Accordingly, free recall has been extensively studied using behavioral methods. However, the neural mechanisms that support free recall have not been fully investigated due to technical challenges associated with...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2009.21350
更新日期:2010-10-01 00:00:00
abstract::Metamemory refers to knowledge and monitoring of one's own memory. Metamemory monitoring can be done prospectively with respect to subsequent memory retrieval or retrospectively with respect to previous memory retrieval. In this study, we used fMRI to compare neural activity during prospective feeling-of-knowing and r...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2009.21123
更新日期:2009-09-01 00:00:00
abstract::Sensitivity to temporal change places fundamental limits on object processing in the visual system. An emerging consensus from the behavioral and neuroimaging literature suggests that temporal resolution differs substantially for stimuli of different complexity and for brain areas at different levels of the cortical h...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01002
更新日期:2016-11-01 00:00:00
abstract::The interaction between auditory and visual speech streams is a seamless and surprisingly effective process. An intriguing example is the "McGurk effect": The acoustic syllable /ba/ presented simultaneously with a mouth articulating /ga/ is typically heard as /da/ [McGurk, H., & MacDonald, J. Hearing lips and seeing v...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2008.20152
更新日期:2008-12-01 00:00:00
abstract::Action execution-perception links (mirror mechanism) have been repeatedly suggested to play crucial roles in social cognition. Remarkably, the designs of most studies exploring this topic so far excluded even the simplest traces of social interaction, such as a movement of the observer toward another individual. This ...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00602
更新日期:2014-09-01 00:00:00
abstract::How the cerebellum is involved in the practice and proficiency of non-motor functions is still unclear. We tested whether transcranial direct current stimulation (tDCS) over the cerebellum (cerebellar tDCS) induces after-effects on the practice-dependent increase in the proficiency of a working memory (WM) task (Stern...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2008.20112
更新日期:2008-09-01 00:00:00
abstract::Decision-making algorithms face a basic tradeoff between accuracy and effort (i.e., computational demands). It is widely agreed that humans can choose between multiple decision-making processes that embody different solutions to this tradeoff: Some are computationally cheap but inaccurate, whereas others are computati...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01263
更新日期:2018-10-01 00:00:00
abstract::A neural correlate for phrase boundary perception in music has recently been identified in musicians. It is called music closure positive shift ("music CPS") and has an equivalent in the perception of speech ("language CPS"). The aim of the present study was to investigate the influence of musical expertise and differ...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/089892906775990642
更新日期:2006-03-01 00:00:00
abstract::The stop signal task (SST) is the gold standard experimental model of inhibitory control. However, neither SST condition-contrast (stop vs. go, successful vs. failed stop) purely operationalizes inhibition. Because stop trials include a second, infrequent signal, the stop versus go contrast confounds inhibition with a...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01503
更新日期:2020-04-01 00:00:00
abstract::In a previously conducted randomized placebo-controlled trial, we were able to demonstrate significant visual field enlargement induced by restitution therapy in patients with cerebral lesions [Kasten, E., Wuest, S., Behrens-Bamann, W., & Sabel, B. A. (1998c). Computer-based training for the treatment of partial blind...
journal_title:Journal of cognitive neuroscience
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1162/08989290051137530
更新日期:2000-11-01 00:00:00
abstract::Abstract A neural model is described of how the brain may autonomously learn a body-centered representation of a three-dimensional (3-D) target position by combining information about retinal target position, eye position, and head position in real time. Such a body-centered spatial representation enables accurate mov...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1994.6.4.341
更新日期:1994-10-01 00:00:00
abstract::Changes in several postnatal maturational processes during neural development have been implicated as potential mechanisms underlying critical period phenomena. Lenneberg hypothesized that maturational processes similar to those that govern sensory and motor development may also constrain capabilities for normal langu...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1996.8.3.231
更新日期:1996-07-01 00:00:00
abstract::The posterior STS (pSTS) is an important brain region for perceptual analysis of social cognitive cues. This study seeks to characterize the pattern of network connectivity emerging from the pSTS in three core social perception localizers: biological motion perception, gaze recognition, and the interpretation of movin...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01054
更新日期:2017-02-01 00:00:00
abstract::People can discriminate real words from nonwords even when the latter are orthographically and phonologically word-like, presumably because words activate specific lexical and/or semantic information. We investigated the neural correlates of this identification process using event-related functional magnetic resonance...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/089892903321593108
更新日期:2003-04-01 00:00:00
abstract::We used fMRI to study figure-ground representation and its decay in primary visual cortex (V1). Human observers viewed a motion-defined figure that gradually became camouflaged by a cluttered background after it stopped moving. V1 showed positive fMRI responses corresponding to the moving figure and negative fMRI resp...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_00190
更新日期:2012-04-01 00:00:00
abstract::Goal-irrelevant information may interfere with ongoing task activities if not controlled properly. Evidence suggests that the ability to control interference is connected mainly to the prefrontal cortex (pFC). However, it remains unclear whether gray matter (GM) volume in prefrontal regions influences individual diffe...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn_a_01430
更新日期:2019-10-01 00:00:00
abstract::Cognitive research shows that people typically remember actions they perform better than those that they only watch or imagine doing, but also at times misremember doing actions they merely imagined or planned to do (source memory errors). Neural research suggests some overlap between brain regions engaged during acti...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/089892902317361921
更新日期:2002-04-01 00:00:00
abstract::Language comprehension in everyday life requires the continuous integration of prior discourse context and general world knowledge with the current utterance or sentence. In the neurolinguistic literature, these so-called situation model building processes have been ascribed to the prefrontal cortex or to the right he...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/0898929053747658
更新日期:2005-05-01 00:00:00
abstract::Rhythmicity is a fundamental property of neural activity at multiple spatiotemporal scales, and associated oscillations represent a critical mechanism for communication and transmission of information across brain regions. During development, these oscillations evolve dynamically as a function of neural maturation and...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章,随机对照试验
doi:10.1162/jocn_a_00877
更新日期:2015-12-01 00:00:00
abstract::Abstract Primates are unique among mammals in possessing a region of dorsolateral prefrontal cortex with a well-developed internal granular layer. This region is commonly implicated in higher cognitive functions. Despite the histological distinctiveness of primate dorsolateral prefrontal cortex, the work of Rose, Wool...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1995.7.1.1
更新日期:1995-01-01 00:00:00
abstract::Cortical neurotransmitter availability is known to exert domain-specific effects on cognitive performance. Hence, normal variation in genes with a role in neurotransmission may also have specific effects on cognition. We tested this hypothesis by examining associations between polymorphisms in genes affecting choliner...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/089892905774597281
更新日期:2005-10-01 00:00:00
abstract::Studies attempting to increase working memory (WM) capacity show promise in enhancing related cognitive functions but have also raised criticism in the broader scientific community given the inconsistent findings produced by these studies. Transcranial direct current stimulation (tDCS) has been shown to enhance WM per...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章,随机对照试验
doi:10.1162/jocn_a_00657
更新日期:2014-11-01 00:00:00
abstract::The ability to inhibit saccades toward suddenly appearing peripheral stimuli (prosaccades) and direct them to contralateral locations instead (antisaccades) is a crucial marker of eye movement control. Typically developing infants as young as 4-month-olds can learn to inhibit reflexive saccades to peripheral stimuli, ...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/0898929053467523
更新日期:2005-04-01 00:00:00
abstract::If subjects are required to name the color of the word red printed in blue ink, interference between word meaning and ink color occurs, which slows down reaction time. This effect is well known as the Stroop effect. It is still an unresolved issue how the brain deals with interference in this type of task. To explore ...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2008.20020
更新日期:2008-02-01 00:00:00
abstract::Abstract Three patients with semantic dementia, involving progressive deterioration of semantic memory, performed immediate serial recall of short sequences of familiar words. On the basis of their performance in other tasks of word comprehension and production, the stimuli were selected individually for each patient ...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1994.6.1.57
更新日期:1994-01-01 00:00:00
abstract::Auditory cortical processing of speech-like sounds was studied in 9 dyslexic and 11 normal-reading adults. Noise/square-wave sequences, mimicking transitions from a fricative consonant to a vowel, were presented binaurally once every 1.1 sec and the cortical responses were recorded with a whole-scalp neuromagnetometer...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/08989290260138654
更新日期:2002-07-01 00:00:00
abstract::This investigation combined behavioral and functional neuroimaging measures to explore whether perception of pain is modulated by the target's stigmatized status and whether the target bore responsibility for that stigma. During fMRI scanning, participants were exposed to a series of short video clips featuring age-ma...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.2009.21266
更新日期:2010-05-01 00:00:00
abstract::Theoretical considerations and diverse empirical data from clinical, psycholinguistic, and developmental studies suggest that language comprehension processes are decomposable into separate subsystems, including distinct systems for semantic and grammatical processing. Here we report that event-related potentials (ERP...
journal_title:Journal of cognitive neuroscience
pub_type: 杂志文章
doi:10.1162/jocn.1991.3.2.151
更新日期:1991-04-01 00:00:00