Long working hours and cognitive function: the Whitehall II Study.

Abstract:

:This study examined the association between long working hours and cognitive function in middle age. Data were collected in 1997-1999 (baseline) and 2002-2004 (follow-up) from a prospective study of 2,214 British civil servants who were in full-time employment at baseline and had data on cognitive tests and covariates. A battery of cognitive tests (short-term memory, Alice Heim 4-I, Mill Hill vocabulary, phonemic fluency, and semantic fluency) were measured at baseline and at follow-up. Compared with working 40 hours per week at most, working more than 55 hours per week was associated with lower scores in the vocabulary test at both baseline and follow-up. Long working hours also predicted decline in performance on the reasoning test (Alice Heim 4-I). Similar results were obtained by using working hours as a continuous variable; the associations between working hours and cognitive function were robust to adjustments for several potential confounding factors including age, sex, marital status, education, occupation, income, physical diseases, psychosocial factors, sleep disturbances, and health risk behaviors. This study shows that long working hours may have a negative effect on cognitive performance in middle age.

journal_name

Am J Epidemiol

authors

Virtanen M,Singh-Manoux A,Ferrie JE,Gimeno D,Marmot MG,Elovainio M,Jokela M,Vahtera J,Kivimäki M

doi

10.1093/aje/kwn382

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

596-605

issue

5

eissn

0002-9262

issn

1476-6256

pii

kwn382

journal_volume

169

pub_type

杂志文章
  • Alcohol consumption and changes in blood pressure among African Americans. The Pitt County Study.

    abstract::The Pitt County Study is a longitudinal investigation of anthropometric, psychosocial, and behavioral predictors of hypertension in African Americans who were aged 25-50 years at baseline in 1988. At baseline, a strong dose-response gradient was observed for alcohol consumption and blood pressure for both sexes. The c...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009348

    authors: Curtis AB,James SA,Strogatz DS,Raghunathan TE,Harlow S

    更新日期:1997-11-01 00:00:00

  • Congenital Abnormalities of the Male Reproductive System and Risk of Autism Spectrum Disorders.

    abstract::Androgens have an extensive influence on brain development in regions of the brain that are relevant for autism spectrum disorder (ASD), yet their etiological involvement remains unclear. Hypospadias (abnormal positioning of the urethral opening) and cryptorchidism (undescended testes) are 2 relatively common male bir...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwx367

    authors: Rotem RS,Chodick G,Davidovitch M,Hauser R,Coull BA,Weisskopf MG

    更新日期:2018-04-01 00:00:00

  • Alcohol consumption among white, black, or oriental men and women: Kaiser-Permanente multiphasic health examination data.

    abstract::Alcohol consumption habits as recorded on health checkup questionnaires by 91,659 white, black, or Oriental men and women were studied. Substantial age, sex, and race differences in alcohol consumption were reported. Generally, men drank more than women, drinking was most prevalent among whites and least prevalent amo...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112388

    authors: Klatsky AL,Friedman GD,Siegelaub AB,Gérard MJ

    更新日期:1977-04-01 00:00:00

  • Amyotrophic Lateral Sclerosis and Exposure to Diesel Exhaust in a Danish Cohort.

    abstract::Previous studies have suggested an increased risk of amyotrophic lateral sclerosis (ALS) and other motor neuron diseases for persons in occupations commonly involving exposure to diesel exhaust (DE). In this study, we investigated the association between occupational exposure to DE and odds of ALS. ALS cases were iden...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwy069

    authors: Dickerson AS,Hansen J,Gredal O,Weisskopf MG

    更新日期:2018-08-01 00:00:00

  • Risk of Hospitalization for Cancer, Musculoskeletal Disorders, Injuries, or Poisonings Surrounding Widowhood.

    abstract::Psychological distress has been indicated to affect the risk of death from cardiovascular disease, cancer, and external causes. Mortality from these major causes of death is also known to be elevated after widowhood when distress is at a heightened level. Surprisingly little is known about changes in health other than...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwy184

    authors: Einiö E,Martikainen P

    更新日期:2019-01-01 00:00:00

  • Results of a rubella screening program for hospital employees: a five-year review (1986-1990).

    abstract::The Barnes Hospital Employee Health Service (St. Louis, Missouri) rubella screening program was evaluated over the 5-year period between January 1, 1986, and December 31, 1990. A total of 6,969 new employees were hired, and 6,115 (87.7%) were screened for evidence of rubella immunity by the Employee Health Service. Ru...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116913

    authors: Fraser V,Spitznagel E,Medoff G,Dunagan WC

    更新日期:1993-11-01 00:00:00

  • Work activity in pregnancy, preventive measures, and the risk of preterm delivery.

    abstract::The objective of this case-control study was to evaluate whether occupational conditions during pregnancy are associated with preterm delivery (PTD). Women whose work conditions changed following the use of a legally justified preventive measure (withdrawal from work or job reassignment) were also compared with those ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/aje/kwm171

    authors: Croteau A,Marcoux S,Brisson C

    更新日期:2007-10-15 00:00:00

  • Association of black carbon with cognition among children in a prospective birth cohort study.

    abstract::While studies show that ultrafine and fine particles can be translocated from the lungs to the central nervous system, the possible neurodegenerative effect of air pollution remains largely unexplored. The authors examined the relation between black carbon, a marker for traffic particles, and cognition among 202 Bosto...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwm308

    authors: Suglia SF,Gryparis A,Wright RO,Schwartz J,Wright RJ

    更新日期:2008-02-01 00:00:00

  • Comparison of Calipers for Matching on the Disease Risk Score.

    abstract::Previous studies have compared calipers for propensity score (PS) matching, but none have considered calipers for matching on the disease risk score (DRS). We used Medicare claims data to perform 3 cohort studies of medication initiators: a study of raloxifene versus alendronate in 1-year nonvertebral fracture risk, a...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwv302

    authors: Connolly JG,Gagne JJ

    更新日期:2016-05-15 00:00:00

  • Aluminum and silica in drinking water and the risk of Alzheimer's disease or cognitive decline: findings from 15-year follow-up of the PAQUID cohort.

    abstract::The authors examined associations between exposure to aluminum or silica from drinking water and risk of cognitive decline, dementia, and Alzheimer's disease among elderly subjects followed for 15 years (1988-2003). They actively searched for incident cases of dementia among persons aged 65 years or over living in 91 ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwn348

    authors: Rondeau V,Jacqmin-Gadda H,Commenges D,Helmer C,Dartigues JF

    更新日期:2009-02-15 00:00:00

  • Factors associated with the distribution of fasting plasma glucose in an adult community.

    abstract::The fasting plasma glucose (FPG) was measured in 4170 nondiabetic adult residents of a suburban California community. At all ages the median FPG in men was higher (103-107 mg/dl) than the median FPG in women (96-104 mg/dl). FPG levels correlated weakly with obesity, and male-female differences persisted after adjustme...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113021

    authors: Barrett-Connor E

    更新日期:1980-10-01 00:00:00

  • Test-retest reliability of the cognitive lifetime drinking history.

    abstract::A new measure of lifetime alcohol consumption, the Cognitive Lifetime Drinking History (CLDH) uses beverage-specific questions on drink sizes and assesses drinking patterns to enhance recall. Two methods of establishing drinking intervals were examined: 1) floating--the respondent's report of when drinking changed, an...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009225

    authors: Russell M,Marshall JR,Trevisan M,Freudenheim JL,Chan AW,Markovic N,Vána JE,Priore RL

    更新日期:1997-12-01 00:00:00

  • Estimating relative risk functions in case-control studies using a nonparametric logistic regression.

    abstract::The authors describe an approach to the analysis of case-control studies in which the exposure variables are continuous, i.e., quantitative variables, and one wishes neither to categorize levels of the exposure variable nor to assume a log-linear relation between level of exposure and disease risk. A dose-response ass...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a008970

    authors: Zhao LP,Kristal AR,White E

    更新日期:1996-09-15 00:00:00

  • Predicting risk of type 2 diabetes mellitus with genetic risk models on the basis of established genome-wide association markers: a systematic review.

    abstract::This study aimed to evaluate the predictive performance of genetic risk models based on risk loci identified and/or confirmed in genome-wide association studies for type 2 diabetes mellitus. A systematic literature search was conducted in the PubMed/MEDLINE and EMBASE databases through April 13, 2012, and published da...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,评审

    doi:10.1093/aje/kwt123

    authors: Bao W,Hu FB,Rong S,Rong Y,Bowers K,Schisterman EF,Liu L,Zhang C

    更新日期:2013-10-15 00:00:00

  • Duration of tick bites in a Lyme disease-endemic area.

    abstract::Regression equations, based on scutal index (body length/scutal width), were developed to determine the duration of attachment for nymphal and adult female lxodes scapularis ticks. Feeding times were calculated for 444 nymphal and 300 female ticks submitted by bite victims between 1985 and 1989 in Westchester County, ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a008728

    authors: Falco RC,Fish D,Piesman J

    更新日期:1996-01-15 00:00:00

  • Subtype-specific transmission probabilities for human immunodeficiency virus type 1 among injecting drug users in Bangkok, Thailand.

    abstract::The Bangkok (Thailand) Metropolitan Administration cohort of injecting drug users (IDUs) consisted of 1,209 IDUs initially seronegative for human immunodeficiency virus (HIV) who were followed from 1995 to 1998 at 15 Administration drug treatment clinics. At enrollment and approximately every 4 months thereafter, part...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/155.2.159

    authors: Hudgens MG,Longini IM Jr,Vanichseni S,Hu DJ,Kitayaporn D,Mock PA,Halloran ME,Satten GA,Choopanya K,Mastro TD

    更新日期:2002-01-15 00:00:00

  • Nutritional factors and gastric cancer in Spain.

    abstract::A case-control study on diet and gastric cancer, carried out in selected areas of four regions of Spain (Aragon, Castile, Catalonia, and Galicia) in 1988 and 1989, included 354 cases of histologically confirmed gastric adenocarcinoma and 354 controls matched by age, sex, and area of residence. Cases and controls were ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117029

    authors: González CA,Riboli E,Badosa J,Batiste E,Cardona T,Pita S,Sanz JM,Torrent M,Agudo A

    更新日期:1994-03-01 00:00:00

  • Racial variations in vision.

    abstract::This study determined the distributions of uncorrected visual acuity and of refractive error in representative groups of Australian Aborigines and Australians of European origin aged 20-30 years. The methodology used in this study and its verification are described in detail. As a group, the Aborigines have significan...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113067

    authors: Taylor HR

    更新日期:1981-01-01 00:00:00

  • Longitudinal association of serum carotenoids and tocopherols with hostility: the CARDIA Study.

    abstract::Hostility is a personality trait associated with increased risk of coronary heart disease. No study has reported the association between hostility and antioxidants, which may be mediators for atherosclerosis. CARDIA (Coronary Artery Risk Development in Young Adults) Study participants were 3,579 men and women 18-30 ye...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/aje/kwm267

    authors: Ohira T,Hozawa A,Iribarren C,Daviglus ML,Matthews KA,Gross MD,Jacobs DR Jr

    更新日期:2008-01-01 00:00:00

  • Education and the risk for Alzheimer's disease: sex makes a difference. EURODEM pooled analyses. EURODEM Incidence Research Group.

    abstract::The hypothesis that a low educational level increases the risk for Alzheimer's disease remains controversial. The authors studied the association of years of schooling with the risk for incident dementia and Alzheimer's disease by using pooled data from four European population-based follow-up studies. Dementia cases ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a010149

    authors: Letenneur L,Launer LJ,Andersen K,Dewey ME,Ott A,Copeland JR,Dartigues JF,Kragh-Sorensen P,Baldereschi M,Brayne C,Lobo A,Martinez-Lage JM,Stijnen T,Hofman A

    更新日期:2000-06-01 00:00:00

  • Calcium, dairy foods, and risk of incident and fatal prostate cancer: the NIH-AARP Diet and Health Study.

    abstract::Calcium and dairy foods in relation to prostate cancer were examined in the National Institutes of Health (NIH)-AARP (formerly known as the American Association of Retired Persons) Diet and Health Study (1995/1996-2001). Diet was assessed with a food frequency questionnaire at baseline. Multivariate relative risks and...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwm268

    authors: Park Y,Mitrou PN,Kipnis V,Hollenbeck A,Schatzkin A,Leitzmann MF

    更新日期:2007-12-01 00:00:00

  • Binge drinking during pregnancy--is it possible to obtain valid information on a weekly basis?

    abstract::It has been suggested that future research into the adverse effects of binge drinking in pregnancy should take into account the time of binge drinking, and a method has been proposed. In a representative sample of 1,311 pregnant Danish women in 2000, the agreement between two different measures of binge drinking durin...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwh095

    authors: Kesmodel U,Frydenberg M

    更新日期:2004-04-15 00:00:00

  • Marginal structural Cox models for estimating the association between β-interferon exposure and disease progression in a multiple sclerosis cohort.

    abstract::Longitudinal observational data are required to assess the association between exposure to β-interferon medications and disease progression among relapsing-remitting multiple sclerosis (MS) patients in the "real-world" clinical practice setting. Marginal structural Cox models (MSCMs) can provide distinct advantages ov...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwu125

    authors: Karim ME,Gustafson P,Petkau J,Zhao Y,Shirani A,Kingwell E,Evans C,van der Kop M,Oger J,Tremlett H

    更新日期:2014-07-15 00:00:00

  • Diabetes Pathology and Risk of Primary Open-Angle Glaucoma: Evaluating Causal Mechanisms by Using Genetic Information.

    abstract::Although type 2 diabetes (T2D) predicts glaucoma, the potential for unmeasured confounding has hampered causal conclusions. We performed separate sample genetic instrumental variable analyses using the Genetic Epidemiology Research Study on Adult Health and Aging cohort (n = 69,685; 1995-2013) to estimate effects of T...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwv204

    authors: Shen L,Walter S,Melles RB,Glymour MM,Jorgenson E

    更新日期:2016-01-15 00:00:00

  • Methods for pooling results of epidemiologic studies: the Pooling Project of Prospective Studies of Diet and Cancer.

    abstract::With the growing number of epidemiologic publications on the relation between dietary factors and cancer risk, pooled analyses that summarize results from multiple studies are becoming more common. Here, the authors describe the methods being used to summarize data on diet-cancer associations within the ongoing Poolin...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwj127

    authors: Smith-Warner SA,Spiegelman D,Ritz J,Albanes D,Beeson WL,Bernstein L,Berrino F,van den Brandt PA,Buring JE,Cho E,Colditz GA,Folsom AR,Freudenheim JL,Giovannucci E,Goldbohm RA,Graham S,Harnack L,Horn-Ross PL,Krogh V,L

    更新日期:2006-06-01 00:00:00

  • Association of ambient fine particles with out-of-hospital cardiac arrests in New York City.

    abstract::Cardiovascular morbidity has been associated with particulate matter (PM) air pollution, although the relation between pollutants and sudden death from cardiac arrest has not been established. This study examined associations between out-of-hospital cardiac arrests and fine PM (of aerodynamic diameter ≤2.5 μm, or PM(2...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwq217

    authors: Silverman RA,Ito K,Freese J,Kaufman BJ,De Claro D,Braun J,Prezant DJ

    更新日期:2010-10-15 00:00:00

  • Racial discrimination and breast cancer incidence in US Black women: the Black Women's Health Study.

    abstract::Perceived discrimination may contribute to somatic disease. The association between perceived discrimination and breast cancer incidence was assessed in the Black Women's Health Study. In 1997, participants completed questions on perceived discrimination in two domains: "everyday" discrimination (e.g., being treated a...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwm056

    authors: Taylor TR,Williams CD,Makambi KH,Mouton C,Harrell JP,Cozier Y,Palmer JR,Rosenberg L,Adams-Campbell LL

    更新日期:2007-07-01 00:00:00

  • Determinants of the incidence of childhood asthma: a two-stage case-control study.

    abstract::Extensive literature exists on potential risk factors for childhood asthma. To the authors' knowledge, no investigators have yet attempted to disentangle the effects of those determinants within a single study setting. The authors aimed to evaluate the independent effects of 47 potential determinants (from the prenata...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwn309

    authors: Martel MJ,Rey E,Malo JL,Perreault S,Beauchesne MF,Forget A,Blais L

    更新日期:2009-01-15 00:00:00

  • Changes in weight at the end of life: characterizing weight loss by time to death in a cohort study of older men.

    abstract::The purpose of this analysis was to characterize the natural history of weight change in the years prior to death among older persons and to examine how this pattern varies according to longevity and cause of death. Weight trajectories were analyzed by using data from 800 male decedents from the Baltimore Longitudinal...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwq168

    authors: Alley DE,Metter EJ,Griswold ME,Harris TB,Simonsick EM,Longo DL,Ferrucci L

    更新日期:2010-09-01 00:00:00

  • Exploring the role of diet in modifying the effect of known disease determinants: application to risk factors of liver cirrhosis.

    abstract::The analysis of the combined effects of nutritional factors with other putative disease determinants in log-linear or logistic models is methodologically complicated by the strong multicollinearity between nutritional factors, resulting in poor precision in estimating the parameters. Furthermore, the generally used mu...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117572

    authors: Corrao G,Ferrari PA,Galatola G

    更新日期:1995-12-01 00:00:00