Abstract：
PURPOSE:To evaluate the level of matrix metalloproteinase-9 (MMP-9) activity in lens epithelial cells (LECs) derived from different types of cataract in patients having phacoemulsification. SETTING:Iladevi Cataract & IOL Research Centre, Memnagar, Ahmedabad, India. METHODS:This observational study of 275 patients having phacoemulsification was performed to evaluate the level of MMP-9 activity in LECs. All anterior lens capsules harboring the LECs and derived from the surgical curvilinear capsulorhexis were obtained during phacoemulsification. The anterior lens capsule samples were processed to analyze MMP-9 activity using a succinylated gelatin assay. The samples were grouped based on age and on pure cataract type. RESULTS:The level of MMP-9 activity in LECs was highest in eyes with cortical cataract. A significant difference in the level of MMP-9 activity was found in different types of cataract (P<.001). The highest level of MMP-9 activity was in patients older than 60 years. The MMP-9 activity increased gradually with age irrespective of cataract type (P<.001). CONCLUSIONS:A significant difference was observed in the level of MMP-9 activity between different types of cataract. The activity of MMP-9 was highest in eyes with cortical cataract. The level of MMP-9 activity increased with age in the LECs of patients with age-related cataract.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Alapure BV,Praveen MR,Gajjar D,Vasavada AR,Rajkumar S,Johar Kdoi
10.1016/j.jcrs.2008.08.016subject
Has Abstractpub_date
2008-12-01 00:00:00pages
2063-7issue
12eissn
0886-3350issn
1873-4502pii
S0886-3350(08)00859-6journal_volume
34pub_type
杂志文章abstract：:Interlenticular opacification (ILO) developed 7 months after secondary acrylic piggyback lens implantation in which the anterior lens was placed in the bag. This resulted in glare and a hyperopic shift. Treating the ILO with the neodymium:YAG laser successfully reduced the glare and corrected the hyperopic shift. ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(01)00865-3
更新日期：2001-09-01 00:00:00
abstract：PURPOSE:To assess the precision of ocular biometry with a new noncontact optical low-coherence interferometer (Aladdin) in healthy subjects and patients with cataracts. SETTING:Eye Hospital of Wenzhou Medical University, Wenzhou, China. DESIGN:Observational cross-sectional study. METHODS:Eyes from healthy subjects a...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2015.10.062
更新日期：2015-10-01 00:00:00
abstract：:A capsulorhexis may be difficult to perform in the absence of a red fundus reflex. Using 0.1 mL of trypan blue 0.1% to stain the anterior capsule in 30 patients with a mature cataract enabled us to visualize the capsulorhexis during phacoemulsification. No adverse reactions were observed up to 12 months after surgery....
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0886-3350(99)80004-2
更新日期：1999-01-01 00:00:00
abstract：:A simplified anesthesia technique for sutureless scleral tunnel, small incision, one-port phacoemulsification is described. Step 1: Mild intravenous sedation is achieved with 1 mg of midazolam and 10 mg of propofol. Step 2: A tetracaine- or preservative-free-lidocaine-soaked Weck cell sponge is applied to the superior...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(98)80342-8
更新日期：1998-12-01 00:00:00
abstract：:A patient with bilateral Salzmann's nodular degeneration developed a myopic shift of 9 diopters in the right eye and 5 diopters in the left eye after removal of his nodules. This previously unreported complication of removal of peripheral corneal pathology is discussed in light of our current understanding of keratore...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80658-x
更新日期：1994-11-01 00:00:00
abstract：:Multifocal intraocular lenses (MIOLs) have been designed to provide better uncorrected near visual acuity than monofocal IOLs. However, the increase in depth of focus is combined with a significant decrease in contrast sensitivity and glare. We implanted a new zonal-progressive MIOL (AMO Array) in 31 eyes of 25 patien...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0886-3350(13)80217-9
更新日期：1995-09-01 00:00:00
abstract：PURPOSE:To evaluate and compare the efficacy of topical versus retrobulbar anesthesia for cataract surgery performed by a surgeon newly converting to the topical technique. SETTING:Department of Ophthalmology, Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. METHODS:Ninety patients were prospectively ...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0886-3350(98)80143-0
更新日期：1998-06-01 00:00:00
abstract：:The prophylactic intraoperative use of mitomycin-C (MMC) to prevent haze and scarring after excimer laser surface ablation (phototherapeutic/photorefractive keratectomy [PTK/PRK]) in an eye with a previous laser in situ keratomileusis (LASIK) flap buttonhole with epithelial ingrowth is described. A well-centered butto...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.06.035
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:To evaluate the visual and economic benefits of same-day bilateral cataract surgery versus separate-day bilateral cataract surgery in the United States. SETTING:Private practice, Amarillo, Texas, USA. DESIGN:Prospective controlled nonrandomized clinical trial. METHODS:A cohort of patients having same-day bil...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2014.07.034
更新日期：2015-04-01 00:00:00
abstract：:We describe a technique for femtosecond laser-assisted bag-in-the-lens (BIL) intraocular lens (IOL) implantation. Anterior capsulotomy and lens division into small pieces are performed by the laser. A fluid-filled interface makes it possible to re-dock the laser to the eye for posterior capsulotomy after the eye has b...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2013.07.014
更新日期：2013-09-01 00:00:00
abstract：:One hundred and thirty-three eyes of 103 patients had photorefractive keratectomy with a slit scan mode excimer laser for myopia ranging from -6.00 to -22.00 diopters (D). The epithelium was removed with 20% ethanol, and the ablation was done with a tapered profile surrounding the optical zone. Patients were divided i...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80526-3
更新日期：1995-07-01 00:00:00
abstract：:We used the finite element method to evaluate different capsulotomy techniques. Nucleus expression was simulated in a computer model to visualize stress distribution in the anterior capsule. The finite element model demonstrated that the capsulorhexis edge is strong because of low and uniform stress distribution in th...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80176-9
更新日期：1994-07-01 00:00:00
abstract：UNLABELLED:We describe a recently developed chopper, the retrochopper, and a technique for managing black and brunescent cataracts. The technique enables the surgeon to effectively disassemble the nucleus and perform a safe procedure with a short learning curve. FINANCIAL DISCLOSURE:No author has a financial or propri...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2013.03.015
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To evaluate intraocular pressure (IOP) during femtosecond laser-assisted cataract surgery using a fluid-filled interface. SETTING:Ruhr University Eye Clinic, Bochum, Germany. DESIGN:Prospective clinical trial. METHODS:The absolute IOP was measured with a modified Schiotz tonometer before and after laser-assi...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.jcrs.2012.10.038
更新日期：2013-01-01 00:00:00
abstract：:We report a case in which the capsular bag with an intraocular lens (IOL) and a capsular tension ring (CTR) dislocated into the vitreous. The dislocated foldable posterior chamber IOL and CTR were removed with a pars plana vitrectomy and exchanged with a scleral-fixated IOL. No complications occurred intraoperatively ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2006.05.016
更新日期：2006-10-01 00:00:00
abstract：:From the beginning of nuclear fragment removal to the end, we progressively reduce all the parameters, ie, energy, vacuum, and aspiration flow rate, in a step-by-step manner proportionate to the posterior capsule exposure. This promotes adaptation of various parameters to the appropriate stages of surgery and allows t...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(03)00121-4
更新日期：2003-06-01 00:00:00
abstract：:Lens manufacturers do not usually supply information about the central thickness of an intraocular lens optic. This paper describes a method to calculate the central lens thickness from variables normally supplied by the manufacturer, i.e., the total lens power in situ, the edge thickness, the optic diameter, and some...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80278-7
更新日期：1993-01-01 00:00:00
abstract：:Four different posterior chamber lens designs were used in 1,845 consecutive, unselected extracapsular cataract extractions performed over a 31-month period in Vejle, Denmark. Ninety-seven eyes (5.3%) required a posterior capsulotomy during a postoperative observation period ranging from two to 32 months. At 16 months...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(88)80143-3
更新日期：1988-07-01 00:00:00
abstract：PURPOSE:To observe changes in intraocular pressure (IOP), the manner in which the eye is suctioned, and the effect of the number of suction ports. SETTING:Department of Ophthalmology, Tokyo Dental College, Suidobashi Hospital, Tokyo, Japan. METHODS:Suction rings with single or dual ports were made of transparent acry...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2004.06.085
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:To evaluate the custom-contoured ablation pattern (C-CAP) method as a tool for providing customized laser ablations for decentered ablations based on corneal topography data. SETTING:Department of Ophthalmology, Stanford University, Stanford, California, USA. METHODS:In a prospective noncomparative interventi...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2003.12.052
更新日期：2004-08-01 00:00:00
abstract：PURPOSE:To evaluate anterior chamber angle alterations after phakic intraocular lens (pIOL) implantation using the Pentacam rotating Scheimpflug camera (Oculus) and the effect on intraocular pressure (IOP) and anterior chamber inflammation. SETTING:Department of Ophthalmology, Keio University School of Medicine, Tokyo...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.04.033
更新日期：2008-08-01 00:00:00
abstract：PURPOSE:To determine the level of residual spherical aberration that gives the best objective and subjective quality of image after cataract surgery with intraocular lens (IOL) implantation. SETTING:Department of Ophthalmology, CHU Bretonneau, Tours, France. DESIGN:Cohort study. METHODS:Six months after microincisio...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.12.056
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:To determine the sex hormone levels in the serum and aqueous humor in patients with age-related cataract and the corresponding hormone receptors in cataract lens epithelial cells (LECs). SETTING:Research Laboratory, International Intraocular Implant Training Center, Tianjin Medical University, Tianjin, China. ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(02)01436-0
更新日期：2003-01-01 00:00:00
abstract：UNLABELLED:We report a case of bilateral corneal opacities in a laser in situ keratomileusis (LASIK) patient who subsequently had carbon dioxide (CO(2)) laser skin resurfacing. The presumed etiology of the visually significant corneal opacities was late-onset diffuse lamellar keratitis (DLK), secondary to traumatic cor...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2011.03.027
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:To ascertain whether the change in refraction caused by paired lamellating corneal incisions in cadaver eyes could be achieved in living eyes and whether wound healing influences this effect. SETTING:Virchow Hospital Eye Clinic, Humboldt University, Berlin, Germany. METHODS:This prospective study included 45 ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(97)80342-2
更新日期：1997-03-01 00:00:00
abstract：:We describe a small-incision technique that reduces the phacoemulsification time. It reduces the risk for strong intraocular inflammation after surgery and posterior capsule rupture during surgery in young patients with uveitis. ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.03.047
更新日期：2008-08-01 00:00:00
abstract：:Phakic intraocular lens (IOL) implantation is an increasingly popular option in surgical correction of refractive error. To date, reports of long-term morbidity are infrequent in the literature. We encountered 3 patients who experienced corneal decompensation and cataract progression following angle-fixated anterior c...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.04.031
更新日期：2005-11-01 00:00:00
abstract：PURPOSE:Comparison of lens capsule-related complications resulting from femtosecond laser-assisted capsulotomy and manual capsulorhexis in patients with white cataracts. SETTING:Eye Center, Second Affiliated Hospital, Zhejiang Medical School, Hangzhou, China. DESIGN:Prospective consecutive nonrandomized comparative c...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2018.10.037
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:To describe a method for optimizing the treatment of astigmatism using vector analysis of both refractive and corneal topographic values. SETTING:Cheltenham Eye Centre, Melbourne, Australia. METHODS:This study evaluated a method of vector analysis for planning surgery that uses both preoperative topographic a...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(97)80153-8
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:To compare visual outcomes in normal and complicated laser in situ keratomileusis (LASIK) flaps constructed with a femtosecond laser. SETTING:Wilford Hall Ambulatory Surgical Center, San Antonio, Texas. DESIGN:Retrospective chart review. METHODS:The main outcome measures were uncorrected distance visual acui...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2015.05.024
更新日期：2015-11-01 00:00:00
