Ischemic acute pancreatitis: clinical features of 11 patients and review of the literature.

Abstract:

BACKGROUND:Besides alcohol and gallstones, pancreatic ischemia can cause acute pancreatitis (AP). This entity should be considered when no other reasons can be defined. The aim of the current study was to define ischemic AP with its pathophysiologic, radiologic, and clinical conditions. METHODS:Eleven patients with ischemic AP of different origin were analyzed regarding course, severity, and outcome, as well as diagnostic and therapeutic measures. RESULTS:Ischemic AP was caused by hemorrhage and hypotension (7 patients) or mesenteric macrovessel occlusion (4 patients). Therapy was conservative (4 patients) or operative with hemostasis, necrosectomy, and drainage (7 patients). Seven patients died within 38 days, and 4 patients recovered. CONCLUSION:Pancreatic hypoperfusion is an important etiology of AP. Severity of the disease ranges from moderate reversible changes to severe courses with fatal outcome. The indication for surgical intervention in ischemic AP is more aggressive; diagnostic and conservative therapeutic procedures are similar to AP of other etiologies.

journal_name

Am J Surg

authors

Hackert T,Hartwig W,Fritz S,Schneider L,Strobel O,Werner J

doi

10.1016/j.amjsurg.2008.04.011

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

450-4

issue

4

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(08)00526-6

journal_volume

197

pub_type

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